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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Ebf3
Z-value: 0.51
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Transcription factors associated with Ebf3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ebf3 | rn6_v1_chr1_-_209641123_209641123 | 0.01 | 9.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_-_15274917 Show fit | 0.39 |
ENSRNOT00000019650
|
progastricsin |
|
| chr10_-_15603649 Show fit | 0.35 |
ENSRNOT00000051483
|
hemoglobin alpha, adult chain 2 |
|
| chr10_+_77537340 Show fit | 0.26 |
ENSRNOT00000003297
|
transmembrane protein 100 |
|
| chr7_-_28715224 Show fit | 0.25 |
ENSRNOT00000065899
|
PARP1 binding protein |
|
| chr2_-_202816562 Show fit | 0.20 |
ENSRNOT00000020401
|
family with sequence similarity 46, member C |
|
| chr10_-_91047177 Show fit | 0.19 |
ENSRNOT00000003986
|
complement C1q like 1 |
|
| chr1_+_123015746 Show fit | 0.17 |
ENSRNOT00000013483
|
MAGE family member L2 |
|
| chr6_+_133576568 Show fit | 0.17 |
ENSRNOT00000085933
|
delta like non-canonical Notch ligand 1 |
|
| chr2_+_187347602 Show fit | 0.17 |
ENSRNOT00000025384
|
nestin |
|
| chr10_-_38838272 Show fit | 0.16 |
ENSRNOT00000089495
|
sosondowah ankyrin repeat domain family member A |
Network of associatons between targets according to the STRING database.
First level regulatory network of Ebf3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
| 0.0 | 0.3 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.0 | 0.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.0 | 0.3 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 0.3 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 0.2 | GO:0045105 | intermediate filament polymerization or depolymerization(GO:0045105) |
| 0.0 | 0.2 | GO:0061743 | motor learning(GO:0061743) |
| 0.0 | 0.2 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.0 | 0.2 | GO:0051127 | positive regulation of actin nucleation(GO:0051127) |
| 0.0 | 0.1 | GO:0071529 | cementum mineralization(GO:0071529) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 0.2 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.0 | 0.1 | GO:0046691 | intracellular canaliculus(GO:0046691) |
| 0.0 | 0.1 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.1 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 0.0 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.0 | 0.0 | GO:0045298 | tubulin complex(GO:0045298) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0031720 | haptoglobin binding(GO:0031720) |
| 0.0 | 0.3 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.0 | 0.2 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.0 | 0.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 0.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.0 | 0.1 | GO:0001605 | adrenomedullin receptor activity(GO:0001605) |
| 0.0 | 0.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.0 | 0.1 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.0 | 0.1 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.0 | 0.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 0.1 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |