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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Ebf1
Z-value: 1.22
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Transcription factors associated with Ebf1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ebf1 | rn6_v1_chr10_+_23661343_23661343 | -0.69 | 1.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_14348046 Show fit | 0.90 |
ENSRNOT00000018630
|
cadherin-related family member 1 |
|
| chr9_-_15274917 Show fit | 0.81 |
ENSRNOT00000019650
|
progastricsin |
|
| chr8_-_117932518 Show fit | 0.75 |
ENSRNOT00000028130
|
cathelicidin antimicrobial peptide |
|
| chr1_+_83003841 Show fit | 0.62 |
ENSRNOT00000057384
|
carcinoembryonic antigen-related cell adhesion molecule 4 |
|
| chr7_-_143966863 Show fit | 0.54 |
ENSRNOT00000018828
|
Sp7 transcription factor |
|
| chr10_-_15590220 Show fit | 0.53 |
ENSRNOT00000048977
|
hemoglobin alpha, adult chain 2 |
|
| chr9_+_10535340 Show fit | 0.51 |
ENSRNOT00000075408
|
zinc and ring finger 4 |
|
| chr1_-_101175570 Show fit | 0.50 |
ENSRNOT00000073918
|
golgi-associated, olfactory signaling regulator |
|
| chr7_+_11769400 Show fit | 0.49 |
ENSRNOT00000044417
|
junctional sarcoplasmic reticulum protein 1 |
|
| chr4_-_124113242 Show fit | 0.49 |
ENSRNOT00000015944
|
thyrotropin releasing hormone |
Network of associatons between targets according to the STRING database.
First level regulatory network of Ebf1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0030317 | sperm motility(GO:0030317) |
| 0.1 | 1.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.1 | 1.0 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 1.0 | GO:1905144 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.0 | 0.9 | GO:0010759 | positive regulation of macrophage chemotaxis(GO:0010759) |
| 0.2 | 0.7 | GO:0071224 | cellular response to peptidoglycan(GO:0071224) |
| 0.0 | 0.7 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.0 | 0.7 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.0 | 0.7 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.2 | 0.6 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 1.2 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.2 | 0.8 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 0.8 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.7 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
| 0.0 | 0.7 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 0.6 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.0 | 0.6 | GO:0042581 | specific granule(GO:0042581) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 1.0 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.0 | 1.0 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.0 | 1.0 | GO:0070888 | E-box binding(GO:0070888) |
| 0.3 | 0.9 | GO:0031720 | haptoglobin binding(GO:0031720) |
| 0.1 | 0.9 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.0 | 0.9 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.9 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.0 | 0.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.2 | 0.7 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 1.1 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.9 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.8 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 0.5 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.5 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 0.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.4 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 1.4 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 1.0 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.0 | 0.9 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.5 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.5 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.5 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 0.4 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |