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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for E2f8

Z-value: 0.26

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Transcription factors associated with E2f8

Gene Symbol Gene ID Gene Info
ENSRNOG00000022537 E2F transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f8rn6_v1_chr1_-_104202591_104202591-0.672.2e-01Click!

Activity profile of E2f8 motif

Sorted Z-values of E2f8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_16395029 0.10 ENSRNOT00000001700
nudix hydrolase 1
chr11_-_83867203 0.07 ENSRNOT00000002394
chordin
chr1_+_221558093 0.06 ENSRNOT00000077274
membrane anchored junction protein
chr19_+_14523554 0.06 ENSRNOT00000084271
ENSRNOT00000064731
minichromosome maintenance complex component 5
chr4_-_179904844 0.05 ENSRNOT00000085386
lamin tail domain containing 1
chr14_+_110676090 0.04 ENSRNOT00000029513
Fanconi anemia, complementation group L
chr4_+_157554794 0.04 ENSRNOT00000024116
inhibitor of growth family, member 4
chr10_-_89699836 0.04 ENSRNOT00000084311
ets variant 4
chr8_-_39201588 0.04 ENSRNOT00000011226
STT3A, catalytic subunit of the oligosaccharyltransferase complex
chr3_-_80052953 0.04 ENSRNOT00000018998
damage specific DNA binding protein 2
chr2_+_197682000 0.03 ENSRNOT00000066821
HORMA domain containing 1
chr1_+_185863043 0.03 ENSRNOT00000079072
SRY box 6
chr2_-_28423762 0.03 ENSRNOT00000022864
basic transcription factor 3
chr9_-_61975640 0.03 ENSRNOT00000085744
boule homolog, RNA binding protein
chr1_-_32362359 0.03 ENSRNOT00000079987
solute carrier family 6 member 3
chr9_-_64573660 0.03 ENSRNOT00000021299
protein boule-like
chr11_-_57993548 0.03 ENSRNOT00000002957
nectin cell adhesion molecule 3
chr1_+_220009397 0.03 ENSRNOT00000084410
RNA binding motif protein 4B
chr5_+_154522119 0.03 ENSRNOT00000072618
E2F transcription factor 2
chr3_-_150073721 0.03 ENSRNOT00000022428
E2F transcription factor 1
chr8_+_108958046 0.02 ENSRNOT00000079618
ENSRNOT00000066917
stromal antigen 1
chr4_+_62703779 0.02 ENSRNOT00000014832
nucleoporin 205
chr10_+_90622992 0.02 ENSRNOT00000032856
meiosis specific with coiled-coil domain
chr3_+_2158995 0.02 ENSRNOT00000010270
zinc finger, MYND-type containing 19
chr13_+_48679774 0.02 ENSRNOT00000075674
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr14_+_82356916 0.02 ENSRNOT00000040229
stem-loop binding protein
chr7_+_54859104 0.02 ENSRNOT00000087341
calcyphosine 2
chr4_+_179905116 0.02 ENSRNOT00000052352
tubulin, alpha 3A
chr1_+_257901985 0.02 ENSRNOT00000073015
helicase, lymphoid specific
chr6_+_43884678 0.02 ENSRNOT00000091551
ribonucleotide reductase regulatory subunit M2
chr11_-_86890390 0.02 ENSRNOT00000046183
tRNA methyltransferase 2 homolog A
chr1_+_257766691 0.02 ENSRNOT00000088148
helicase, lymphoid specific
chr10_+_93354003 0.02 ENSRNOT00000008140
methyltransferase like 2B
chr1_+_101687855 0.02 ENSRNOT00000028546
ENSRNOT00000091597
D-box binding PAR bZIP transcription factor
chr3_-_160891190 0.02 ENSRNOT00000019386
syndecan 4
chr10_-_56839437 0.02 ENSRNOT00000090338
B-cell CLL/lymphoma 6B
chr1_+_257614731 0.02 ENSRNOT00000075680
lymphocyte-specific helicase-like
chr3_+_159421671 0.02 ENSRNOT00000010343
myeloblastosis oncogene-like 2
chr14_+_106393959 0.01 ENSRNOT00000092168
WD repeat containing planar cell polarity effector
chr3_-_151486693 0.01 ENSRNOT00000073736
ENSRNOT00000071099
growth differentiation factor 5
chr11_+_86890585 0.01 ENSRNOT00000002579
RAN binding protein 1
chr6_+_95816749 0.01 ENSRNOT00000008880
SIX homeobox 6
chr2_+_186630278 0.01 ENSRNOT00000021604
similar to elongation protein 4 homolog
chr14_-_106393670 0.01 ENSRNOT00000011429
malate dehydrogenase 1
chr20_+_25990656 0.01 ENSRNOT00000081254
leucine rich repeat transmembrane neuronal 3
chr2_-_259898525 0.01 ENSRNOT00000082253
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr7_+_54859326 0.01 ENSRNOT00000039141
calcyphosine 2
chr11_-_89510871 0.01 ENSRNOT00000035247
protein kinase, DNA activated, catalytic polypeptide
chr9_-_10757954 0.01 ENSRNOT00000075265
ubiquitin-like with PHD and ring finger domains 1
chr2_+_24546536 0.01 ENSRNOT00000014036
orthopedia homeobox
chr18_+_30036887 0.01 ENSRNOT00000077824
protocadherin alpha 4
chr10_+_75335146 0.01 ENSRNOT00000073005
serine and arginine rich splicing factor 1
chr9_-_10757720 0.01 ENSRNOT00000083848
ubiquitin-like with PHD and ring finger domains 1
chr19_-_44231157 0.01 ENSRNOT00000046126
lysyl-tRNA synthetase
chr1_+_257615088 0.01 ENSRNOT00000083183
lymphocyte-specific helicase-like
chrX_-_112159458 0.01 ENSRNOT00000087403
testis expressed 13B
chr6_+_128973956 0.01 ENSRNOT00000075399
family with sequence similarity 181, member A
chr8_-_55408464 0.00 ENSRNOT00000066893
salt-inducible kinase 2
chr5_+_147185474 0.00 ENSRNOT00000000134
adenylate kinase 2
chr14_+_44580216 0.00 ENSRNOT00000088674
ENSRNOT00000003907
replication factor C subunit 1
chr1_+_174767960 0.00 ENSRNOT00000013362
WEE1 G2 checkpoint kinase
chr14_+_48726045 0.00 ENSRNOT00000086646
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_+_147375350 0.00 ENSRNOT00000010674
tyrosyl-tRNA synthetase
chr19_+_37652969 0.00 ENSRNOT00000041970
capping protein regulator and myosin 1 linker 2
chr18_+_56364620 0.00 ENSRNOT00000068535
ENSRNOT00000086033
platelet derived growth factor receptor beta
chr2_-_231881939 0.00 ENSRNOT00000074644
La ribonucleoprotein domain family, member 7
chr6_+_76675418 0.00 ENSRNOT00000076169
ENSRNOT00000010948
ENSRNOT00000082286
breast cancer metastasis-suppressor 1-like
breast cancer metastasis-suppressor 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)