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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Dlx5_Dlx4
Z-value: 0.55
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Transcription factors associated with Dlx5_Dlx4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Dlx5 | rn6_v1_chr4_-_32392007_32392007 | -0.55 | 3.3e-01 | Click! |
| Dlx4 | rn6_v1_chr10_-_82963919_82963919 | -0.15 | 8.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_66417741 Show fit | 0.60 |
ENSRNOT00000007662
|
neuronal differentiation 1 |
|
| chr2_+_145174876 Show fit | 0.55 |
ENSRNOT00000040631
|
mab-21 like 1 |
|
| chr2_-_185852759 Show fit | 0.41 |
ENSRNOT00000049461
|
mab-21 like 2 |
|
| chr20_-_9855443 Show fit | 0.30 |
ENSRNOT00000090275
ENSRNOT00000066266 |
trefoil factor 3 |
|
| chr7_-_13751271 Show fit | 0.28 |
ENSRNOT00000009931
|
solute carrier family 1 member 6 |
|
| chr12_-_17186679 Show fit | 0.27 |
ENSRNOT00000001730
|
UNC homeobox |
|
| chr5_-_151459037 Show fit | 0.26 |
ENSRNOT00000064472
ENSRNOT00000087836 |
synaptotagmin-like 1 |
|
| chrM_+_7758 Show fit | 0.23 |
ENSRNOT00000046201
|
mitochondrially encoded ATP synthase 8 |
|
| chr4_+_148782479 Show fit | 0.22 |
ENSRNOT00000018133
|
similar to hypothetical protein MGC6835 |
|
| chr2_+_58724855 Show fit | 0.21 |
ENSRNOT00000089609
|
calcyphosine-like |
Network of associatons between targets according to the STRING database.
First level regulatory network of Dlx5_Dlx4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.0 | 0.5 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 0.5 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.3 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.0 | 0.3 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.0 | 0.2 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.0 | 0.2 | GO:0052697 | xenobiotic glucuronidation(GO:0052697) |
| 0.0 | 0.2 | GO:0021707 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.0 | 0.2 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.0 | 0.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.4 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.2 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.0 | 0.1 | GO:0070821 | azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821) |
| 0.0 | 0.1 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.0 | 0.1 | GO:0045025 | mitochondrial degradosome(GO:0045025) |
| 0.0 | 0.1 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.0 | 0.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.0 | 0.1 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 0.1 | GO:1990716 | axonemal central apparatus(GO:1990716) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) |
| 0.0 | 0.7 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.3 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 0.3 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
| 0.0 | 0.3 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.1 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.0 | 0.1 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
| 0.0 | 0.1 | GO:0046573 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.0 | 0.1 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.3 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.2 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.0 | 0.1 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |