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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Dlx5_Dlx4

Z-value: 0.55

Motif logo

Transcription factors associated with Dlx5_Dlx4

Gene Symbol Gene ID Gene Info
ENSRNOG00000010905 distal-less homeobox 5
ENSRNOG00000004399 distal-less homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dlx5rn6_v1_chr4_-_32392007_32392007-0.553.3e-01Click!
Dlx4rn6_v1_chr10_-_82963919_82963919-0.158.1e-01Click!

Activity profile of Dlx5_Dlx4 motif

Sorted Z-values of Dlx5_Dlx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_66417741 0.60 ENSRNOT00000007662
neuronal differentiation 1
chr2_+_145174876 0.55 ENSRNOT00000040631
mab-21 like 1
chr2_-_185852759 0.41 ENSRNOT00000049461
mab-21 like 2
chr20_-_9855443 0.30 ENSRNOT00000090275
ENSRNOT00000066266
trefoil factor 3
chr7_-_13751271 0.28 ENSRNOT00000009931
solute carrier family 1 member 6
chr12_-_17186679 0.27 ENSRNOT00000001730
UNC homeobox
chr5_-_151459037 0.26 ENSRNOT00000064472
ENSRNOT00000087836
synaptotagmin-like 1
chrM_+_7758 0.23 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr4_+_148782479 0.22 ENSRNOT00000018133
similar to hypothetical protein MGC6835
chr2_+_58724855 0.21 ENSRNOT00000089609
calcyphosine-like
chr4_+_94696965 0.20 ENSRNOT00000064696
glutamate ionotropic receptor delta type subunit 2
chrX_-_123980357 0.18 ENSRNOT00000049435
reproductive homeobox 8
chr1_-_71373605 0.17 ENSRNOT00000034854
galanin-like peptide
chrM_+_9451 0.17 ENSRNOT00000041241
mitochondrially encoded NADH dehydrogenase 3
chr7_-_139223116 0.16 ENSRNOT00000086559
endonuclease, poly(U)-specific
chr15_+_87722221 0.16 ENSRNOT00000082688
sciellin
chr5_-_22769907 0.15 ENSRNOT00000047805
ENSRNOT00000076167
ENSRNOT00000076507
ENSRNOT00000076113
ENSRNOT00000083779
aspartate-beta-hydroxylase
chr17_-_2705123 0.15 ENSRNOT00000024940
olfactory receptor 1652
chr17_+_24416651 0.14 ENSRNOT00000024458
CD83 molecule
chr2_-_147819335 0.14 ENSRNOT00000057909
ankyrin repeat and ubiquitin domain containing 1
chr10_-_63176463 0.14 ENSRNOT00000004717
solute carrier family 6 member 4
chr6_-_123577695 0.14 ENSRNOT00000006604
forkhead box N3
chrM_+_3904 0.13 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr1_-_38538987 0.13 ENSRNOT00000090406
ENSRNOT00000071275
zinc finger protein 728-like
chr7_+_144052061 0.13 ENSRNOT00000020103
ENSRNOT00000091378
anti-Mullerian hormone receptor type 2
chr5_+_6373583 0.12 ENSRNOT00000084749

chr9_+_95161157 0.12 ENSRNOT00000071200
UDP glucuronosyltransferase family 1 member A5
chr5_+_24410863 0.12 ENSRNOT00000010591
tumor protein p53 inducible nuclear protein 1
chr2_+_187951344 0.11 ENSRNOT00000027123
signal sequence receptor, beta
chrX_+_131617798 0.11 ENSRNOT00000074384
proline rich 32
chr4_+_157726941 0.11 ENSRNOT00000025081
vesicle-associated membrane protein 1
chr2_+_178117466 0.11 ENSRNOT00000065115
ENSRNOT00000084198
similar to hypothetical protein FLJ25371
chr3_-_7498555 0.11 ENSRNOT00000017725
BarH-like homeobox 1
chr10_-_88670430 0.10 ENSRNOT00000025547
hypocretin neuropeptide precursor
chr1_-_198104109 0.10 ENSRNOT00000026186
sulfotransferase family 1A member 1
chr1_+_264260505 0.10 ENSRNOT00000018815
wingless-type MMTV integration site family, member 8B
chr2_-_205212681 0.10 ENSRNOT00000022575
thyroid stimulating hormone, beta
chr7_-_54855557 0.10 ENSRNOT00000039475
GLI pathogenesis-related 1 like 1
chr1_-_67065797 0.10 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr1_+_86972244 0.10 ENSRNOT00000036907
Ras and Rab interactor-like
chr19_-_37528011 0.10 ENSRNOT00000059628
agouti related neuropeptide
chrM_+_7919 0.09 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chr3_-_40477754 0.09 ENSRNOT00000091168

chr3_+_138174054 0.09 ENSRNOT00000007946
barrier to autointegration factor 2
chr1_+_55219773 0.09 ENSRNOT00000041610
similar to putative protein kinase
chr13_-_44345735 0.09 ENSRNOT00000005006
transmembrane protein 163
chr9_+_117795132 0.09 ENSRNOT00000086943
A-kinase anchor inhibitor 1
chr19_-_28751584 0.09 ENSRNOT00000079270

chr1_+_213886775 0.09 ENSRNOT00000020864
plakophilin 3
chr10_+_56662561 0.09 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr3_+_150801289 0.09 ENSRNOT00000035060
microtubule-associated protein 1 light chain 3 alpha
chr19_-_49448072 0.09 ENSRNOT00000014997
C-x(9)-C motif containing 2
chr7_+_120153184 0.09 ENSRNOT00000013538
galectin 1
chr17_-_43807540 0.09 ENSRNOT00000074763
similar to CG31613-PA
chr13_+_89386023 0.08 ENSRNOT00000086223
Fc fragment of IgG receptor IIIa
chr15_+_33606124 0.08 ENSRNOT00000065210

chrX_-_88321834 0.08 ENSRNOT00000020364
cation-dependent mannose-6-phosphate receptor-like
chr20_+_1749716 0.08 ENSRNOT00000048856
olfactory receptor 1735
chr3_-_161294125 0.08 ENSRNOT00000021143
spermatogenesis associated 25
chr10_+_55626741 0.08 ENSRNOT00000008492
aurora kinase B
chrX_+_11084317 0.08 ENSRNOT00000031808
ENSRNOT00000093745
similar to RIKEN cDNA 1810030O07
chr13_-_47916185 0.08 ENSRNOT00000087793
dual specificity tyrosine phosphorylation regulated kinase 3
chr10_+_88227360 0.08 ENSRNOT00000041033
eukaryotic translation initiation factor 1
chr8_-_72204730 0.08 ENSRNOT00000023810
F-box and leucine-rich repeat protein 22
chr7_+_136182224 0.08 ENSRNOT00000008159
transmembrane protein 117
chr10_+_55712043 0.08 ENSRNOT00000010141
arachidonate lipoxygenase 3
chr6_+_8886591 0.08 ENSRNOT00000091510
ENSRNOT00000089174
SIX homeobox 3
chr20_-_9291610 0.08 ENSRNOT00000000650
glyoxalase 1
chr12_+_18679789 0.08 ENSRNOT00000001863
cytochrome P450, family 3, subfamily a, polypeptide 9
chr3_-_101547478 0.08 ENSRNOT00000006203
fin bud initiation factor homolog (zebrafish)
chr1_-_80783898 0.08 ENSRNOT00000045306
carcinoembryonic antigen-related cell adhesion molecule 16
chr4_-_162025090 0.08 ENSRNOT00000085887
ENSRNOT00000009904
killer cell lectin-like receptor subfamily B, member 1A
chrM_+_9870 0.08 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr2_+_93758919 0.08 ENSRNOT00000077782
fatty acid binding protein 12
chr10_+_55627025 0.07 ENSRNOT00000091016
aurora kinase B
chr16_-_75346122 0.07 ENSRNOT00000018529
defensin alpha 24
chr20_+_4966817 0.07 ENSRNOT00000081527
ENSRNOT00000081265
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_266141581 0.07 ENSRNOT00000078187
ENSRNOT00000051951
RPE65, retinoid isomerohydrolase
chr14_-_79464770 0.07 ENSRNOT00000008932
GrpE-like 1, mitochondrial
chr4_-_117575154 0.07 ENSRNOT00000075813
probable N-acetyltransferase CML2-like
chr7_+_140608434 0.07 ENSRNOT00000001163

chr5_-_12526962 0.07 ENSRNOT00000092104
suppression of tumorigenicity 18
chr1_-_116153722 0.07 ENSRNOT00000041605
formyl peptide receptor 3
chr3_+_47578384 0.07 ENSRNOT00000082769
proteasome 26S subunit, non-ATPase 14
chr12_+_41463922 0.07 ENSRNOT00000089378
cilia and flagella associated protein 73
chr9_-_1012450 0.07 ENSRNOT00000051449
ribosomal protein S20-like
chrX_-_64702441 0.07 ENSRNOT00000051132
APC membrane recruitment protein 1
chr4_-_30338679 0.07 ENSRNOT00000012050
paraoxonase 3
chr4_-_159399634 0.07 ENSRNOT00000089193
NADH:ubiquinone oxidoreductase subunit A9
chr15_+_11298478 0.07 ENSRNOT00000007672
leucine rich repeat containing 3B
chr15_+_44411865 0.07 ENSRNOT00000017566
potassium channel tetramerization domain containing 9
chr10_+_56662242 0.07 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr1_-_102741581 0.07 ENSRNOT00000016254
similar to Serum amyloid A-3 protein precursor
chr12_+_19196611 0.07 ENSRNOT00000001801
alpha-2-glycoprotein 1, zinc-binding
chr19_+_320906 0.07 ENSRNOT00000041664

chrX_+_28593405 0.06 ENSRNOT00000071708
thymosin beta 4, X-linked
chr3_-_94808861 0.06 ENSRNOT00000038464
proline rich and Gla domain 4
chr5_-_134638150 0.06 ENSRNOT00000013480
testis expressed 38
chr20_+_13817795 0.06 ENSRNOT00000036518
glutathione S-transferase, theta 3
chr2_+_200397967 0.06 ENSRNOT00000025821
regenerating family member 4
chr1_-_101095594 0.06 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr4_+_31333970 0.06 ENSRNOT00000064866
coiled-coil domain-containing protein 132-like
chr4_+_147844658 0.06 ENSRNOT00000042673
H1 histone family, member O, oocyte-specific
chr1_+_169145445 0.06 ENSRNOT00000034019
hypothetical protein LOC499219
chr7_-_130350570 0.06 ENSRNOT00000055805
outer dense fiber of sperm tails 3B
chr5_+_137257287 0.06 ENSRNOT00000037160
ELOVL fatty acid elongase 1
chrM_+_10160 0.06 ENSRNOT00000042928
mitochondrially encoded NADH dehydrogenase 4
chr18_-_27520295 0.06 ENSRNOT00000027544
GDNF family receptor alpha 3
chr17_+_76008807 0.06 ENSRNOT00000070895
enoyl CoA hydratase domain containing 3
chr13_-_102643223 0.06 ENSRNOT00000003155
H2.0-like homeobox
chr4_-_176528110 0.06 ENSRNOT00000049569
solute carrier organic anion transporter family, member 1A2
chr4_-_176909075 0.06 ENSRNOT00000067489
ATP binding cassette subfamily C member 9
chr1_-_215536980 0.06 ENSRNOT00000027344
interferon induced transmembrane protein 10
chr4_-_51844331 0.06 ENSRNOT00000003593
G protein-coupled receptor 37
chr3_-_2490392 0.06 ENSRNOT00000014993
SS nuclear autoantigen 1
chr5_+_78384444 0.06 ENSRNOT00000034978
similar to hypothetical protein 4933430I17
chr3_-_103745236 0.06 ENSRNOT00000006876
NUT midline carcinoma, family member 1
chr1_+_213636093 0.06 ENSRNOT00000019642
proteasome 26S subunit, non-ATPase 13
chr8_+_99632803 0.06 ENSRNOT00000087190
phospholipid scramblase 1
chr10_+_13836128 0.06 ENSRNOT00000012720
phosphoglycolate phosphatase
chr10_-_58608907 0.06 ENSRNOT00000010533
aryl hydrocarbon receptor-interacting protein-like 1
chr3_-_8955538 0.06 ENSRNOT00000040570
similar to 60S ribosomal protein L38
chr1_-_282492912 0.06 ENSRNOT00000047883

chr4_+_6827429 0.06 ENSRNOT00000071737
Ras homolog enriched in brain
chr8_+_91820783 0.06 ENSRNOT00000043351
similar to mitochondrial ribosomal protein L41
chrX_+_63542191 0.06 ENSRNOT00000073955
apolipoprotein O
chr12_-_19167015 0.06 ENSRNOT00000001797
gap junction protein, gamma 3
chr9_+_98113346 0.06 ENSRNOT00000026912
prolactin releasing hormone
chr15_-_30147793 0.06 ENSRNOT00000060399

chr6_+_2216623 0.06 ENSRNOT00000008045
regulator of microtubule dynamics 2
chrY_-_1398030 0.06 ENSRNOT00000088719
ubiquitin specific peptidase 9, Y-linked
chr20_+_44680449 0.06 ENSRNOT00000000728
Traf3 interacting protein 2
chr7_+_29909120 0.05 ENSRNOT00000049362

chr3_-_46942966 0.05 ENSRNOT00000087439
RNA binding motif, single stranded interacting protein 1
chr13_+_67545430 0.05 ENSRNOT00000003405
phosducin
chr9_+_94562839 0.05 ENSRNOT00000022308
LOC363276
chr1_+_105285419 0.05 ENSRNOT00000089693
solute carrier family 6 member 5
chr10_+_56445647 0.05 ENSRNOT00000056870
transmembrane protein 256
chr5_+_128450680 0.05 ENSRNOT00000010700
thioredoxin domain containing 12
chr19_+_37873515 0.05 ENSRNOT00000026163
ENSRNOT00000089921
protein serine kinase H1
chr4_-_170912629 0.05 ENSRNOT00000055691
endoplasmic reticulum protein 27
chr14_-_21299068 0.05 ENSRNOT00000065778
amelotin
chr1_-_216663720 0.05 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chr4_+_70977556 0.05 ENSRNOT00000031984
hypothetical protein LOC680112
chr7_+_72924799 0.05 ENSRNOT00000008969
lysosomal protein transmembrane 4 beta
chr19_-_41349681 0.05 ENSRNOT00000080694
ENSRNOT00000059147
Hydin, axonemal central pair apparatus protein
chr3_-_148493225 0.05 ENSRNOT00000012141
p53 and DNA damage regulated 1
chr1_+_22332090 0.05 ENSRNOT00000091252
trace amine-associated receptor 8c (Taar8c), mRNA
chr8_-_22785671 0.05 ENSRNOT00000045384
SPC24, NDC80 kinetochore complex component
chr3_+_16846412 0.05 ENSRNOT00000074266

chr11_-_17684903 0.05 ENSRNOT00000051213
transmembrane protease, serine 15
chr7_-_143324536 0.05 ENSRNOT00000011644
keratin 5
chrM_+_8599 0.05 ENSRNOT00000049683
mitochondrially encoded cytochrome C oxidase III
chr10_+_74413989 0.05 ENSRNOT00000036098
spindle and kinetochore associated complex subunit 2
chr1_-_165606375 0.05 ENSRNOT00000024290
mitochondrial ribosomal protein L48
chr7_-_28711761 0.05 ENSRNOT00000006249
PARP1 binding protein
chr10_-_83898527 0.05 ENSRNOT00000009815
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr13_-_27192592 0.05 ENSRNOT00000040021
serpin family B member 3
chr16_-_31301880 0.05 ENSRNOT00000084847
ENSRNOT00000083943

chr1_+_196095214 0.05 ENSRNOT00000080741
similar to ribosomal protein S15a
chr10_-_44147035 0.05 ENSRNOT00000041113
olfactory receptor 1424
chr11_+_70056624 0.05 ENSRNOT00000002447

chr3_+_94530586 0.05 ENSRNOT00000067860
cleavage stimulation factor subunit 3
chr11_+_36851038 0.05 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chr10_+_103266296 0.05 ENSRNOT00000038852
dynein, axonemal, intermediate chain 2
chr2_-_27287605 0.05 ENSRNOT00000034041
ankyrin repeat and death domain containing 1B
chr14_+_22375955 0.05 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr8_-_96516975 0.05 ENSRNOT00000067996
similar to RIKEN cDNA 4930579C12 gene
chr1_-_220136470 0.05 ENSRNOT00000026812
actinin alpha 3
chr10_+_71217966 0.05 ENSRNOT00000076192
HNF1 homeobox B
chr16_-_6669045 0.05 ENSRNOT00000067639
protein kinase C, delta
chr7_+_18683553 0.05 ENSRNOT00000009425
NADH:ubiquinone oxidoreductase subunit A7
chr16_+_54332660 0.05 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr8_+_99625545 0.05 ENSRNOT00000010689
ENSRNOT00000056727
phospholipid scramblase 1
chr15_-_32888095 0.05 ENSRNOT00000012233
defender against cell death 1
chr2_-_30246010 0.05 ENSRNOT00000023900
methylcrotonoyl-CoA carboxylase 2
chr7_+_107413691 0.05 ENSRNOT00000007587
PHD finger protein 20-like protein 1
chr9_-_73948583 0.05 ENSRNOT00000018097
myosin, light chain 1
chr16_+_37177443 0.05 ENSRNOT00000014083
centrosomal protein 44
chr10_+_13230158 0.05 ENSRNOT00000075648
common salivary protein 1
chr4_-_158705885 0.05 ENSRNOT00000087115
ENSRNOT00000026685
neurotrophin 3
chr10_-_72196437 0.05 ENSRNOT00000029769
phosphatidylinositol glycan anchor biosynthesis, class W
chr5_-_17061361 0.05 ENSRNOT00000089318
proenkephalin
chr14_-_6533524 0.05 ENSRNOT00000079795
ATP-binding cassette, subfamily G (WHITE), member 3-like 1
chr8_+_122076759 0.05 ENSRNOT00000012545
cytoplasmic linker associated protein 2
chr1_-_224698514 0.05 ENSRNOT00000024234
solute carrier family 22, member 25
chrX_-_77675487 0.05 ENSRNOT00000042799
cysteinyl leukotriene receptor 1
chr5_-_174921 0.05 ENSRNOT00000056239
TIMELESS interacting protein like 1
chr19_+_37282018 0.05 ENSRNOT00000021723
transmembrane protein 208
chr5_-_134927235 0.05 ENSRNOT00000016751
ubiquinol-cytochrome c reductase hinge protein
chr12_-_21746236 0.05 ENSRNOT00000001869
TSC22 domain family protein 4-like
chr1_+_227892956 0.05 ENSRNOT00000028483

chr2_-_187706300 0.05 ENSRNOT00000092349
ENSRNOT00000026414
transmembrane protein 79
chr1_+_102924059 0.05 ENSRNOT00000078137

chr14_-_84662143 0.04 ENSRNOT00000057529
ENSRNOT00000080078
HORMA domain containing 2
chr10_-_87459652 0.04 ENSRNOT00000018804
keratin 40
chr2_-_197991574 0.04 ENSRNOT00000085632
circadian associated repressor of transcription
chr10_-_14324170 0.04 ENSRNOT00000035513
ENSRNOT00000090587
hematological and neurological expressed 1-like
chr2_-_197991198 0.04 ENSRNOT00000056322
circadian associated repressor of transcription
chr6_-_91581262 0.04 ENSRNOT00000034507

Network of associatons between targets according to the STRING database.

First level regulatory network of Dlx5_Dlx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0036446 myofibroblast differentiation(GO:0036446) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0033123 positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
0.0 0.1 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0 0.1 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0035565 regulation of pronephros size(GO:0035565) hepatoblast differentiation(GO:0061017)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:2000373 phosphatidylserine exposure on apoptotic cell surface(GO:0070782) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.0 GO:0042335 cuticle development(GO:0042335) cornification(GO:0070268)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.0 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.0 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.0 GO:0002434 immune complex clearance(GO:0002434)
0.0 0.0 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.0 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.1 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.0 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
0.0 0.0 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.0 0.0 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.0 0.1 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.0 GO:0071338 submandibular salivary gland formation(GO:0060661) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.0 GO:0050828 regulation of liquid surface tension(GO:0050828)
0.0 0.0 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) phenotypic switching(GO:0036166) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070821 azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0045025 mitochondrial degradosome(GO:0045025)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.1 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.0 GO:0097149 centralspindlin complex(GO:0097149)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.7 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0070976 TIR domain binding(GO:0070976)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.0 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.0 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules