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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Cux1

Z-value: 0.73

Motif logo

Transcription factors associated with Cux1

Gene Symbol Gene ID Gene Info
ENSRNOG00000001424 cut-like homeobox 1
ENSRNOG00000059116 cut-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cux1rn6_v1_chr12_+_23151180_23151180-0.019.8e-01Click!

Activity profile of Cux1 motif

Sorted Z-values of Cux1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_22859622 0.37 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr19_-_39267928 0.34 ENSRNOT00000027686
transmembrane p24 trafficking protein 6
chr2_-_157058194 0.33 ENSRNOT00000076409

chr15_-_30147793 0.31 ENSRNOT00000060399

chr15_+_36865548 0.30 ENSRNOT00000076460
poly (ADP-ribose) polymerase family, member 4
chr5_+_142875773 0.27 ENSRNOT00000082120
ENSRNOT00000056496
EPH receptor A10
chr11_-_60882379 0.27 ENSRNOT00000002799
CD200 receptor 1
chr2_+_23289374 0.26 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr11_-_62451149 0.26 ENSRNOT00000093686
ENSRNOT00000081443
zinc finger and BTB domain containing 20
chr4_+_61814974 0.23 ENSRNOT00000074951
aldo-keto reductase family 1 member B10
chr2_-_220838905 0.23 ENSRNOT00000078914

chr6_+_64224861 0.23 ENSRNOT00000093159
ENSRNOT00000093664
patatin-like phospholipase domain containing 8
chr8_-_22150005 0.21 ENSRNOT00000041678
tyrosine kinase 2
chrM_+_11736 0.21 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr3_+_114355798 0.21 ENSRNOT00000024658
ENSRNOT00000036435
solute carrier family 28 member 2
chr10_+_31647898 0.20 ENSRNOT00000066536
similar to kidney injury molecule 1
chr1_+_213583606 0.20 ENSRNOT00000088899

chr13_+_51534025 0.20 ENSRNOT00000006637
synaptotagmin 2
chrX_-_4945944 0.19 ENSRNOT00000077238
lysine demethylase 6A
chr4_+_152450126 0.19 ENSRNOT00000076930
RAD52 homolog, DNA repair protein
chr2_-_192381716 0.19 ENSRNOT00000064950

chr13_-_47397890 0.19 ENSRNOT00000005505
complement component 4 binding protein, beta
chr2_+_86891092 0.17 ENSRNOT00000077162
ENSRNOT00000083066
zinc finger protein 457-like
chr2_-_257546799 0.17 ENSRNOT00000089370
ENSRNOT00000090367
mitoguardin 1
chr6_+_99356509 0.16 ENSRNOT00000008416
A-kinase anchoring protein 5
chr8_-_69466618 0.16 ENSRNOT00000042925
iduronate 2-sulfatase
chr7_+_20262680 0.16 ENSRNOT00000046378
similar to hypothetical protein 4930509O22
chr20_-_7654428 0.15 ENSRNOT00000045044
t-complex 11
chr8_+_12355767 0.15 ENSRNOT00000068445
family with sequence similarity 76, member B
chr15_+_47470863 0.15 ENSRNOT00000072438
similar to Plasma kallikrein precursor (Plasma prekallikrein) (Kininogenin) (Fletcher factor)
chr8_+_48438259 0.15 ENSRNOT00000059813
membrane frizzled-related protein
chr10_-_85684138 0.15 ENSRNOT00000017989
phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr17_-_69711689 0.15 ENSRNOT00000041925
aldo-keto reductase family 1, member C12
chrX_-_70460536 0.14 ENSRNOT00000076824
PDZ domain containing 11
chr8_-_5429581 0.14 ENSRNOT00000044174
dynein cytoplasmic 2 heavy chain 1
chr17_+_16455026 0.14 ENSRNOT00000022932
zinc finger protein 169
chr9_+_66889028 0.14 ENSRNOT00000087194
calcium responsive transcription factor
chr10_+_66942398 0.14 ENSRNOT00000018986
RAB11 family interacting protein 4
chr9_+_49903085 0.14 ENSRNOT00000022601
similar to expressed sequence AI597479
chrX_+_137934484 0.13 ENSRNOT00000049046
hypothetical protein LOC317588
chr16_-_19097329 0.13 ENSRNOT00000030617
similar to 1700030K09Rik protein
chr1_-_43638161 0.13 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr14_-_67170361 0.13 ENSRNOT00000005477
slit guidance ligand 2
chrX_-_78911601 0.13 ENSRNOT00000003188
similar to RIKEN cDNA 2610002M06
chr3_-_119330345 0.13 ENSRNOT00000077398
ENSRNOT00000079191
transient receptor potential cation channel, subfamily M, member 7
chr3_-_146396299 0.12 ENSRNOT00000040188
ENSRNOT00000008931
adipocyte plasma membrane associated protein
chr3_+_113918629 0.12 ENSRNOT00000078978
ENSRNOT00000037168
CTD small phosphatase like 2
chr4_+_2053712 0.12 ENSRNOT00000045086
ring finger protein 32
chr7_+_127081978 0.12 ENSRNOT00000022945
TBC1 domain family, member 22a
chr19_+_14489983 0.12 ENSRNOT00000075435
ZFP14 zinc finger protein
chr18_-_56500941 0.12 ENSRNOT00000024704
HMG-box containing 3
chr6_-_115616766 0.12 ENSRNOT00000006143
ENSRNOT00000045870
SEL1L ERAD E3 ligase adaptor subunit
chr5_-_137125737 0.12 ENSRNOT00000088532

chr9_-_83253458 0.12 ENSRNOT00000041689
Eph receptor A4
chr11_-_31180616 0.11 ENSRNOT00000065535
ENSRNOT00000052033
ENSRNOT00000002812
synaptojanin 1
chr8_-_96547568 0.11 ENSRNOT00000078343
similar to RIKEN cDNA 4930579C12 gene
chr9_-_92530938 0.11 ENSRNOT00000064875
solute carrier family 16, member 14
chr10_-_46720907 0.11 ENSRNOT00000083093
ENSRNOT00000067866
target of myb1 like 2 membrane trafficking protein
chr1_-_81043340 0.11 ENSRNOT00000051473
zinc finger protein 111
chr3_+_147073160 0.11 ENSRNOT00000012690
syndecan binding protein 2
chr14_+_39368530 0.11 ENSRNOT00000084367
cytochrome c oxidase subunit 7B2
chr4_+_179481263 0.11 ENSRNOT00000021284
electron transfer flavoprotein regulatory factor 1
chr12_-_18120476 0.11 ENSRNOT00000080364
similar to Hypothetical protein A430033K04
chr12_+_8725517 0.11 ENSRNOT00000001243
solute carrier family 46, member 3
chr7_-_135800481 0.11 ENSRNOT00000029097
pseudouridylate synthase 7-like
chr12_+_9360672 0.11 ENSRNOT00000088957
fms-related tyrosine kinase 3
chr7_-_94774569 0.11 ENSRNOT00000036399
DNA replication and sister chromatid cohesion 1
chr3_-_55951584 0.11 ENSRNOT00000036585
FAST kinase domains 1
chr10_+_83081168 0.10 ENSRNOT00000035023
tachykinin 4 (hemokinin)
chrX_+_28072826 0.10 ENSRNOT00000039796
FERM and PDZ domain containing 4
chr3_+_79823945 0.10 ENSRNOT00000014484
CUGBP, Elav-like family member 1
chr12_-_5773036 0.10 ENSRNOT00000041365
FRY microtubule binding protein
chr3_+_63379031 0.10 ENSRNOT00000068199
oxysterol binding protein-like 6
chr10_-_37215899 0.10 ENSRNOT00000006356
SEC24 homolog A, COPII coat complex component
chr17_-_86657473 0.10 ENSRNOT00000078827

chr2_-_236480502 0.10 ENSRNOT00000015020
sphingomyelin synthase 2
chr8_+_48437918 0.10 ENSRNOT00000085578
membrane frizzled-related protein
chr17_+_35396286 0.10 ENSRNOT00000089613
ENSRNOT00000092638
exocyst complex component 2
chr11_+_67555658 0.10 ENSRNOT00000039075
cystatin A (stefin A)
chr6_+_86823684 0.10 ENSRNOT00000086081
ENSRNOT00000006574
Fanconi anemia, complementation group M
chr16_+_11599753 0.10 ENSRNOT00000079833
glutamate ionotropic receptor delta type subunit 1
chr1_+_278557792 0.10 ENSRNOT00000023414
attractin like 1
chr3_-_9936352 0.10 ENSRNOT00000011224
ENSRNOT00000042798
formin binding protein 1
chr12_-_35979193 0.10 ENSRNOT00000071104
transmembrane protein 132B
chr8_-_36467627 0.10 ENSRNOT00000082346
family with sequence similarity 118, member B
chr6_-_108796124 0.10 ENSRNOT00000086545
apoptosis resistant E3 ubiquitin protein ligase 1
chr11_+_38727048 0.10 ENSRNOT00000081537
zinc finger protein 260-like
chr9_-_100479868 0.10 ENSRNOT00000022748
PAS domain containing serine/threonine kinase
chr2_+_34312766 0.10 ENSRNOT00000060962
centromere protein K
chr8_+_32452885 0.10 ENSRNOT00000010423
PR/SET domain 10
chr9_-_89195273 0.10 ENSRNOT00000022281
SPHK1 interactor, AKAP domain containing
chr3_+_79498179 0.10 ENSRNOT00000030750
nucleoporin 160
chr2_-_54963448 0.10 ENSRNOT00000017886
prostaglandin E receptor 4
chr15_-_58171049 0.10 ENSRNOT00000001371
GPALPP motifs containing 1
chr10_-_87153982 0.10 ENSRNOT00000014414
keratin 222
chr7_+_125288081 0.10 ENSRNOT00000085216
parvin, gamma
chr18_-_6587080 0.09 ENSRNOT00000040815
60S ribosomal protein L39
chr1_-_263885169 0.09 ENSRNOT00000030782
conserved helix-loop-helix ubiquitous kinase
chr8_+_116771982 0.09 ENSRNOT00000083240

chr20_-_26589209 0.09 ENSRNOT00000049437
catenin alpha 3
chr1_+_196839321 0.09 ENSRNOT00000020388
lysine demethylase 8
chr5_+_43603043 0.09 ENSRNOT00000009899
Eph receptor A7
chr16_-_81756654 0.09 ENSRNOT00000026653
cullin 4A
chr7_+_15785410 0.09 ENSRNOT00000082664
ENSRNOT00000073235
zinc finger protein 955A
chr18_+_30900291 0.09 ENSRNOT00000060461
protocadherin gamma subfamily B, 7
chr7_-_2961873 0.09 ENSRNOT00000067441
ribosomal protein S15, pseudogene 2
chr3_-_66279155 0.09 ENSRNOT00000079887
ceramide kinase-like
chr7_-_15073052 0.09 ENSRNOT00000037708
zinc finger protein 799
chr5_+_5616483 0.09 ENSRNOT00000011026
nuclear receptor coactivator 2
chr7_+_27174882 0.09 ENSRNOT00000051181
glycosyltransferase 8 domain containing 2
chr2_+_118547190 0.09 ENSRNOT00000083676
ENSRNOT00000090301
ENSRNOT00000013410
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr10_-_38969501 0.09 ENSRNOT00000090691
ENSRNOT00000081309
ENSRNOT00000010029
interleukin 4
chr1_-_37741709 0.09 ENSRNOT00000079186
FAST kinase domains 3
chr13_-_48400632 0.09 ENSRNOT00000074204
arginine vasopressin receptor 1B
chr14_+_100373129 0.09 ENSRNOT00000029980
WD repeat domain 92
chr3_-_90751055 0.09 ENSRNOT00000040741
LRRGT00091
chr17_-_9558624 0.09 ENSRNOT00000036223
ENSRNOT00000083492
beta-1,4-galactosyltransferase 7
chr2_-_170460754 0.09 ENSRNOT00000013009
SLIT and NTRK-like family, member 3
chrX_-_14331486 0.09 ENSRNOT00000067603
retinitis pigmentosa GTPase regulator
chr1_+_228684136 0.08 ENSRNOT00000028608
olfactory receptor 337
chr8_-_71728654 0.08 ENSRNOT00000031207
ENSRNOT00000091751
sorting nexin 22
chr9_+_73528681 0.08 ENSRNOT00000084340
unc-80 homolog, NALCN activator
chr1_+_98228573 0.08 ENSRNOT00000019278
zinc finger protein 850-like
chr4_+_98648545 0.08 ENSRNOT00000008451
eukaryotic translation initiation factor 2 alpha kinase 3
chr8_+_52729003 0.08 ENSRNOT00000081738
neurexophilin and PC-esterase domain family, member 4
chrX_-_37705263 0.08 ENSRNOT00000043666
mitogen-activated protein kinase kinase kinase 15
chr13_+_97838361 0.08 ENSRNOT00000003641
consortin, connexin sorting protein
chr14_-_8600512 0.08 ENSRNOT00000092537
Rho GTPase activating protein 24
chr17_+_9736577 0.08 ENSRNOT00000066586
coagulation factor XII
chr19_+_37873515 0.08 ENSRNOT00000026163
ENSRNOT00000089921
protein serine kinase H1
chr20_-_27301952 0.08 ENSRNOT00000000438
solute carrier family 25 member 16
chr20_+_9791171 0.08 ENSRNOT00000078031
ATP binding cassette subfamily G member 1
chr2_-_219628997 0.08 ENSRNOT00000064484
tRNA methyltransferase 13 homolog
chr10_-_49149479 0.08 ENSRNOT00000004291
zinc finger protein 287
chr3_+_37599728 0.08 ENSRNOT00000090575
replication timing regulatory factor 1
chr2_-_115891097 0.08 ENSRNOT00000013191
SKI-like proto-oncogene
chr2_-_27287605 0.08 ENSRNOT00000034041
ankyrin repeat and death domain containing 1B
chr4_+_114918488 0.08 ENSRNOT00000014249
solute carrier family 4 member 5
chrX_-_105308554 0.08 ENSRNOT00000045556
TATA-box binding protein associated factor 7-like
chr8_+_19888667 0.08 ENSRNOT00000078593
zinc finger protein 317
chr1_-_82344345 0.08 ENSRNOT00000051892
ENSRNOT00000090629
ENSRNOT00000029487
ENSRNOT00000027933
carcinoembryonic antigen related cell adhesion molecule 1
chr15_+_44411865 0.08 ENSRNOT00000017566
potassium channel tetramerization domain containing 9
chr15_-_57805184 0.08 ENSRNOT00000000168
component of oligomeric golgi complex 3
chr14_+_71542057 0.08 ENSRNOT00000082592
ENSRNOT00000083701
ENSRNOT00000084322
prominin 1
chr3_+_155160481 0.08 ENSRNOT00000021133
protein phosphatase 1, regulatory subunit 16B
chr15_+_87722221 0.08 ENSRNOT00000082688
sciellin
chr9_-_20154077 0.08 ENSRNOT00000082904
adhesion G protein-coupled receptor F5
chr7_-_15072703 0.08 ENSRNOT00000087294
zinc finger protein 799
chr8_+_69127708 0.08 ENSRNOT00000013490
small nuclear RNA activating complex, polypeptide 5
chr7_-_139835876 0.08 ENSRNOT00000014258
olfactory receptor 1877
chr16_-_7588841 0.07 ENSRNOT00000084645
methyltransferase like 6
chr4_+_68656928 0.07 ENSRNOT00000016232
taste receptor, type 2, member 108
chr3_-_2770620 0.07 ENSRNOT00000008253
Tnf receptor-associated factor 2
chr10_+_11090314 0.07 ENSRNOT00000086305
coronin 7
chr14_-_46529375 0.07 ENSRNOT00000077306
ENSRNOT00000078682
rRNA promoter binding protein
chr20_-_13994794 0.07 ENSRNOT00000093466
gamma-glutamyltransferase 5
chr10_-_72235888 0.07 ENSRNOT00000039481
zinc finger, HIT-type containing 3
chr11_+_67101714 0.07 ENSRNOT00000078936
CD86 molecule
chr20_-_8202924 0.07 ENSRNOT00000071399
transmembrane protein 217
chr12_-_48254822 0.07 ENSRNOT00000056865
uracil-DNA glycosylase
chr14_+_32257805 0.07 ENSRNOT00000039626

chr10_+_86223336 0.07 ENSRNOT00000038939
hippyragranin
chr7_+_123043503 0.07 ENSRNOT00000026258
ENSRNOT00000086355
TEF, PAR bZIP transcription factor
chr7_+_130474279 0.07 ENSRNOT00000092388
SH3 and multiple ankyrin repeat domains 3
chr1_-_65611815 0.07 ENSRNOT00000036874
zinc finger protein 324
chr17_-_66295014 0.07 ENSRNOT00000023974
5-methyltetrahydrofolate-homocysteine methyltransferase
chr10_-_36322356 0.07 ENSRNOT00000000248
zinc finger protein 354C
chr11_+_83855753 0.07 ENSRNOT00000030686
similar to 60S ribosomal protein L12
chr3_-_16537433 0.07 ENSRNOT00000048523

chr18_-_56728185 0.07 ENSRNOT00000066048
PPARG coactivator 1 beta
chr9_-_5330815 0.07 ENSRNOT00000014548
solute carrier family 5 member 7
chr8_-_12355091 0.07 ENSRNOT00000009318
centrosomal protein 57
chr9_+_10603813 0.07 ENSRNOT00000073991
ENSRNOT00000074469
ENSRNOT00000079999
protein tyrosine phosphatase, receptor type, S
chr1_+_128614138 0.07 ENSRNOT00000076227
ENSRNOT00000078707
tetratricopeptide repeat domain 23
chr5_-_140657745 0.07 ENSRNOT00000019080
major facilitator superfamily domain containing 2A
chr8_+_85259982 0.07 ENSRNOT00000010409
ELOVL fatty acid elongase 5
chr1_-_263910251 0.07 ENSRNOT00000017202
CWF19-like 1, cell cycle control (S. pombe)
chr5_-_169630340 0.07 ENSRNOT00000087043
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr18_-_75207306 0.07 ENSRNOT00000021717
SET binding protein 1
chr5_-_117612123 0.07 ENSRNOT00000065112
dedicator of cytokinesis 7
chr11_-_66878551 0.07 ENSRNOT00000066616
IQ motif containing B1
chr13_-_26812215 0.07 ENSRNOT00000003728
3-ketodihydrosphingosine reductase
chr1_+_116604550 0.07 ENSRNOT00000083587
ubiquitin protein ligase E3A
chr8_+_58120179 0.07 ENSRNOT00000049076
ENSRNOT00000090114
nuclear protein, co-activator of histone transcription
chr19_+_755460 0.07 ENSRNOT00000076560
dynein, cytoplasmic 1 light intermediate chain 2
chr14_-_46657975 0.07 ENSRNOT00000087247
rRNA promoter binding protein
chr20_+_12944786 0.07 ENSRNOT00000048218
pericentrin
chr4_-_6062641 0.07 ENSRNOT00000074846
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr10_-_91661558 0.07 ENSRNOT00000043156

chr2_-_188718704 0.06 ENSRNOT00000028010
zinc finger and BTB domain containing 7B
chr5_-_138545404 0.06 ENSRNOT00000011586
ribosomal modification protein rimK-like family member A
chr18_+_57516347 0.06 ENSRNOT00000082215
predicted gene 9949
chr5_-_78985990 0.06 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr13_+_90301006 0.06 ENSRNOT00000029315
SLAM family member 6
chr4_+_60549197 0.06 ENSRNOT00000071249
ENSRNOT00000075621
exocyst complex component 4
chr20_+_20105047 0.06 ENSRNOT00000082181
ankyrin 3
chr5_+_36555109 0.06 ENSRNOT00000061128
F-box and leucine-rich repeat protein 4
chr5_-_50068706 0.06 ENSRNOT00000084643
origin recognition complex, subunit 3
chr7_+_71293388 0.06 ENSRNOT00000083959
phosphatidylserine synthase 1
chr15_+_3754262 0.06 ENSRNOT00000035100
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Cux1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.2 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.2 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) polyprenol catabolic process(GO:0016095)
0.1 0.1 GO:0072703 response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.2 GO:0036394 amylase secretion(GO:0036394)
0.1 0.2 GO:0072642 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0032197 transposition, RNA-mediated(GO:0032197)
0.0 0.3 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.1 GO:0071623 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
0.0 0.3 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:2001106 fasciculation of motor neuron axon(GO:0097156) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:0043316 cytotoxic T cell degranulation(GO:0043316)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.0 0.1 GO:2000424 T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1904884 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.0 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.1 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:1990379 lipid transport across blood brain barrier(GO:1990379)
0.0 0.1 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.0 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.0 GO:0035700 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:0043060 meiotic metaphase I plate congression(GO:0043060)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
0.0 0.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:2000535 exocyst assembly(GO:0001927) entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.0 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.1 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.0 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.0 GO:0033986 response to methanol(GO:0033986)
0.0 0.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.0 0.0 GO:1902963 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.0 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 0.0 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.0 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.0 GO:0005713 chiasma(GO:0005712) recombination nodule(GO:0005713)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0001565 phorbol ester receptor activity(GO:0001565)
0.0 0.1 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.0 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.0 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1