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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Ctcfl_Ctcf

Z-value: 1.09

Motif logo

Transcription factors associated with Ctcfl_Ctcf

Gene Symbol Gene ID Gene Info
ENSRNOG00000028661 CCCTC-binding factor like
ENSRNOG00000017674 CCCTC-binding factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ctcflrn6_v1_chr3_-_171166454_1711664540.296.3e-01Click!
Ctcfrn6_v1_chr19_+_37600148_376001480.128.5e-01Click!

Activity profile of Ctcfl_Ctcf motif

Sorted Z-values of Ctcfl_Ctcf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_9695292 1.62 ENSRNOT00000036162
proline rich 7 (synaptic)
chr10_-_15600858 0.95 ENSRNOT00000035459
hemoglobin, theta 1B
chr19_+_41482728 0.77 ENSRNOT00000022943
calbindin 2
chr3_+_164424515 0.60 ENSRNOT00000083876
CCAAT/enhancer binding protein beta
chr12_+_47551935 0.59 ENSRNOT00000056932
RGD1560398
chr12_+_24651314 0.58 ENSRNOT00000077016
ENSRNOT00000071569
VPS37D, ESCRT-I subunit
chr16_+_21282467 0.47 ENSRNOT00000065345
YjeF N-terminal domain containing 3
chr6_+_137997335 0.47 ENSRNOT00000006872
transmembrane protein 121
chr10_-_90393317 0.46 ENSRNOT00000028563
family with sequence similarity 171, member A2
chr19_-_26094756 0.42 ENSRNOT00000067780
JunB proto-oncogene, AP-1 transcription factor subunit
chr17_-_13393243 0.40 ENSRNOT00000018252
growth arrest and DNA-damage-inducible, gamma
chr20_-_5618254 0.40 ENSRNOT00000092326
ENSRNOT00000000576
BCL2-antagonist/killer 1
chr8_-_117237229 0.37 ENSRNOT00000071381
kelch domain containing 8B
chr10_-_85049331 0.36 ENSRNOT00000012538
T-box 21
chrX_+_72684329 0.35 ENSRNOT00000057644
DMRT-like family C1c1
chr8_+_71822129 0.35 ENSRNOT00000089147
death-associated protein kinase 2
chr1_+_221792221 0.34 ENSRNOT00000054828
neurexin 2
chr10_+_13723405 0.32 ENSRNOT00000072789
ATP binding cassette subfamily A member 3
chr12_+_48257609 0.29 ENSRNOT00000031658
ENSRNOT00000090277
alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
chr18_-_37776453 0.29 ENSRNOT00000087876
dihydropyrimidinase-like 3
chr5_-_151397603 0.29 ENSRNOT00000076866
G protein-coupled receptor 3
chr16_+_20672374 0.28 ENSRNOT00000063780
similar to RIKEN cDNA 2810428I15
chr15_-_38276159 0.27 ENSRNOT00000084698
ENSRNOT00000015233
mitochondrial calcium uptake 2
chr3_+_148150698 0.27 ENSRNOT00000087075
ENSRNOT00000010251
histocompatibility minor 13
chr14_+_83752393 0.26 ENSRNOT00000081123
selenoprotein M
chr3_+_154395187 0.26 ENSRNOT00000050810
V-set and transmembrane domain containing 2 like
chr7_+_140781799 0.25 ENSRNOT00000087932
DnaJ heat shock protein family (Hsp40) member C22
chr1_-_142724511 0.25 ENSRNOT00000014639
neuromedin B
chr3_-_154627257 0.25 ENSRNOT00000018328
transglutaminase 2
chr6_-_11494459 0.25 ENSRNOT00000021570
potassium two pore domain channel subfamily K member 12
chr4_+_25435873 0.25 ENSRNOT00000000018
STEAP family member 1
chr10_-_46332172 0.24 ENSRNOT00000004475
ras related dexamethasone induced 1
chr11_+_77815181 0.24 ENSRNOT00000002640
claudin 1
chr1_-_101131012 0.24 ENSRNOT00000082283
ENSRNOT00000093498
ENSRNOT00000093559
fms-related tyrosine kinase 3 ligand
ribosomal protein L13A
chr1_-_52962388 0.23 ENSRNOT00000033685
brachyury 2
chr7_-_70452675 0.23 ENSRNOT00000090498

chr11_+_88122271 0.21 ENSRNOT00000002540
stromal cell-derived factor 2-like 1
chr6_-_128989812 0.20 ENSRNOT00000085943
ankyrin repeat and SOCS box protein 2-like
chr16_+_19767264 0.20 ENSRNOT00000051802
ENSRNOT00000092073
occludin/ELL domain containing 1
chr2_-_199771896 0.20 ENSRNOT00000043937
chromodomain helicase DNA binding protein 1-like
chr3_+_72191533 0.20 ENSRNOT00000044319
ubiquitin-conjugating enzyme E2L 6
chr15_-_19575914 0.19 ENSRNOT00000043897

chr5_-_61077627 0.18 ENSRNOT00000015338
SH2 domain containing adaptor protein B
chr5_+_143081326 0.18 ENSRNOT00000067204
MYST/Esa1-associated factor 6
chr10_-_29450644 0.18 ENSRNOT00000087937
adrenoceptor alpha 1B
chr20_-_10680283 0.18 ENSRNOT00000001579
salt-inducible kinase 1
chr6_+_136720582 0.18 ENSRNOT00000086868
kinesin family member 26A
chr11_+_33845463 0.18 ENSRNOT00000041838
carbonyl reductase 1
chr2_+_225827504 0.17 ENSRNOT00000018343
glutamate cysteine ligase, modifier subunit
chr7_-_77159457 0.17 ENSRNOT00000085626
Kruppel-like factor 10
chr10_+_55013703 0.17 ENSRNOT00000032785
phosphoinositide-3-kinase, regulatory subunit 5
chr1_+_175445088 0.17 ENSRNOT00000036718
adrenomedullin
chr2_+_251817694 0.17 ENSRNOT00000019964
similar to RIKEN cDNA 2410004B18
chr13_-_50509916 0.16 ENSRNOT00000076747
renin
chr9_-_43127887 0.16 ENSRNOT00000021685
ankyrin repeat domain 39
chr15_-_29369504 0.16 ENSRNOT00000060297

chrX_+_45637415 0.16 ENSRNOT00000050544
similar to ferritin heavy polypeptide-like 17
chr9_+_10941613 0.16 ENSRNOT00000070794
semaphorin 6B
chr6_+_136720266 0.16 ENSRNOT00000018278
kinesin family member 26A
chr12_+_23151180 0.16 ENSRNOT00000059486
cut-like homeobox 1
chr7_+_12022285 0.15 ENSRNOT00000024080
RNA exonuclease 1 homolog
chr7_-_12424367 0.15 ENSRNOT00000060698
midnolin
chr7_+_2875909 0.15 ENSRNOT00000028244
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr20_+_5050327 0.15 ENSRNOT00000083353
dimethylarginine dimethylaminohydrolase 2
chr1_-_254671596 0.15 ENSRNOT00000025450
5-hydroxytryptamine receptor 7
chr5_-_156141537 0.15 ENSRNOT00000019004
alkaline phosphatase, liver/bone/kidney
chr7_-_11513415 0.15 ENSRNOT00000082486
thimet oligopeptidase 1
chr3_+_160231914 0.15 ENSRNOT00000014411
potassium two pore domain channel subfamily K member 15
chr5_-_157368450 0.14 ENSRNOT00000023143
ENSRNOT00000079855
OTU deubiquitinase 3
chr16_+_9563218 0.14 ENSRNOT00000035915
Rho GTPase activating protein 22
chr1_+_82480195 0.14 ENSRNOT00000028051
transforming growth factor, beta 1
chrX_-_14890606 0.14 ENSRNOT00000049864
similar to RIKEN cDNA B630019K06
chr7_-_2909144 0.14 ENSRNOT00000082518
ENSRNOT00000089074
ENSRNOT00000085644
myosin light chain 6
chr8_-_50526843 0.14 ENSRNOT00000092188

chr9_+_97355924 0.14 ENSRNOT00000026558
atypical chemokine receptor 3
chr3_+_170252901 0.14 ENSRNOT00000005871
melanocortin 3 receptor
chr9_-_92775816 0.14 ENSRNOT00000029635
similar to Nuclear autoantigen Sp-100 (Speckled 100 kDa)
chr7_-_2825498 0.14 ENSRNOT00000086656
ENSRNOT00000031362
nucleic acid binding protein 2
chr7_-_142260896 0.14 ENSRNOT00000073536
small cell adhesion glycoprotein
chr5_+_152606847 0.14 ENSRNOT00000089070
platelet-activating factor acetylhydrolase 2
chr19_+_10519493 0.13 ENSRNOT00000030229
coiled-coil domain containing 102A
chr14_-_84170301 0.13 ENSRNOT00000080413
solute carrier family 35, member E4
chr16_-_20890949 0.13 ENSRNOT00000081977
homer scaffolding protein 3
chr8_-_62424303 0.13 ENSRNOT00000091223
c-src tyrosine kinase
chr19_+_26106838 0.13 ENSRNOT00000035987
hook microtubule-tethering protein 2
chr1_-_80666566 0.13 ENSRNOT00000082125
ENSRNOT00000025388
nectin cell adhesion molecule 2
chr15_+_31948035 0.13 ENSRNOT00000071627

chr3_+_160852164 0.13 ENSRNOT00000019127
recombination signal binding protein for immunoglobulin kappa J region-like
chr9_-_15306465 0.13 ENSRNOT00000019404
fibroblast growth factor receptor substrate 3
chr20_+_3995544 0.12 ENSRNOT00000000527
transporter 2, ATP binding cassette subfamily B member
chr7_-_58587787 0.12 ENSRNOT00000005814
leucine rich repeat containing G protein coupled receptor 5
chr1_-_254671778 0.12 ENSRNOT00000025493
5-hydroxytryptamine receptor 7
chr10_-_68517564 0.12 ENSRNOT00000086961
acid sensing ion channel subunit 2
chr10_-_14092289 0.12 ENSRNOT00000019624
NADH:ubiquinone oxidoreductase subunit B10
chr7_-_138707221 0.12 ENSRNOT00000009199
adhesion molecule with Ig like domain 2
chr18_+_30527705 0.12 ENSRNOT00000027168
protocadherin beta 14
chr10_+_86950557 0.12 ENSRNOT00000014153
insulin-like growth factor binding protein 4
chr14_+_82769642 0.12 ENSRNOT00000065393
C-terminal binding protein 1
chr2_+_198772937 0.11 ENSRNOT00000028812
integrin subunit alpha 10
chr2_-_188471988 0.11 ENSRNOT00000027785
hyperpolarization-activated cyclic nucleotide-gated potassium channel 3
chr1_+_173532803 0.11 ENSRNOT00000021017
eukaryotic translation initiation factor 3, subunit F
chr7_-_11513581 0.11 ENSRNOT00000027045
thimet oligopeptidase 1
chr17_+_70684340 0.11 ENSRNOT00000051067
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr5_-_159602251 0.11 ENSRNOT00000011394
NECAP endocytosis associated 2
chr10_+_105861743 0.10 ENSRNOT00000064410
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr10_+_40543288 0.10 ENSRNOT00000016755
solute carrier family 36 member 1
chr2_-_187133993 0.10 ENSRNOT00000019502
platelet endothelial aggregation receptor 1
chr12_+_13299859 0.10 ENSRNOT00000039191
similar to Protein C7orf26 homolog
chr10_-_109757550 0.10 ENSRNOT00000054957
Rho GDP dissociation inhibitor alpha
chrX_-_45522665 0.10 ENSRNOT00000030771
similar to GS2 gene
chr15_-_23580342 0.10 ENSRNOT00000013331
ENSRNOT00000085767
cornichon family AMPA receptor auxiliary protein 1
chr15_-_33193537 0.10 ENSRNOT00000016401
HAUS augmin-like complex, subunit 4
chr17_+_26785029 0.10 ENSRNOT00000022065
eukaryotic translation elongation factor 1 epsilon 1
chr9_-_10441834 0.10 ENSRNOT00000043704
ribosomal protein L36
chr11_+_73738433 0.10 ENSRNOT00000002353
transmembrane protein 44
chr6_-_46631983 0.10 ENSRNOT00000045963
SRY box 11
chr19_+_37652969 0.10 ENSRNOT00000041970
capping protein regulator and myosin 1 linker 2
chr20_-_5212624 0.10 ENSRNOT00000074261
antigen peptide transporter 2
chr15_-_34444244 0.09 ENSRNOT00000027612
cell death-inducing DFFA-like effector b
chr11_+_36851038 0.09 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chr18_+_30509393 0.09 ENSRNOT00000043846
protocadherin beta 12
chr18_-_57245666 0.09 ENSRNOT00000080365
actin binding LIM protein family, member 3
chr13_-_53108713 0.09 ENSRNOT00000035404
similar to hypothetical protein FLJ10901
chr3_-_11382004 0.09 ENSRNOT00000047921
ENSRNOT00000064039
dynamin 1
chr10_-_86393141 0.09 ENSRNOT00000009485
migration and invasion enhancer 1
chr5_-_164927869 0.09 ENSRNOT00000012080
dorsal inhibitory axon guidance protein
chr3_-_36660758 0.09 ENSRNOT00000006111
Rho family GTPase 3
chr1_+_47605262 0.09 ENSRNOT00000089458
fibronectin type III domain containing 1
chr10_+_66099531 0.09 ENSRNOT00000056192
LYR motif containing 9
chr4_+_121612332 0.09 ENSRNOT00000077374
ENSRNOT00000084494
thioredoxin reductase 3
chr2_+_157854667 0.09 ENSRNOT00000039294

chr6_-_126582034 0.09 ENSRNOT00000010656
ENSRNOT00000080829
inositol-tetrakisphosphate 1-kinase
chr7_-_144272578 0.09 ENSRNOT00000020676
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr8_-_94120433 0.09 ENSRNOT00000080195
ENSRNOT00000014600
ubiquitin protein ligase E3D
chr3_+_168124673 0.09 ENSRNOT00000070809
prefoldin subunit 4
chr2_+_195719543 0.09 ENSRNOT00000028324
CUGBP, Elav-like family member 3
chr1_-_15374850 0.09 ENSRNOT00000016728
peroxisomal biogenesis factor 7
chr1_-_85517360 0.08 ENSRNOT00000026114
EP300 interacting inhibitor of differentiation 2
chr11_-_67756799 0.08 ENSRNOT00000030975
poly (ADP-ribose) polymerase family, member 9
chr20_-_5244386 0.08 ENSRNOT00000070886
RT1 class II, locus DMa
chr3_+_175548174 0.08 ENSRNOT00000091941
adhesion regulating molecule 1
chr3_-_148313810 0.08 ENSRNOT00000010762
Bcl2-like 1
chr7_-_12793711 0.08 ENSRNOT00000013762
paralemmin
chr17_+_31493107 0.08 ENSRNOT00000023611
ENSRNOT00000086264
tubulin, beta 2A class IIa
chr12_+_13716596 0.08 ENSRNOT00000080216
actin, beta
chr20_+_7818289 0.08 ENSRNOT00000042539
peroxisome proliferator-activated receptor delta
chr1_-_89483988 0.08 ENSRNOT00000028603
FXYD domain-containing ion transport regulator 7
chr9_-_121972055 0.08 ENSRNOT00000089735
clusterin-like protein 1
chr7_-_11963268 0.08 ENSRNOT00000080342
ENSRNOT00000025266
casein kinase 1, gamma 2
chr3_+_164274710 0.08 ENSRNOT00000012939
snail family transcriptional repressor 1
chr4_-_56453563 0.08 ENSRNOT00000060362
proline-rich transmembrane protein 4
chr10_-_88266210 0.08 ENSRNOT00000090702
ENSRNOT00000020603
huntingtin-associated protein 1
chr2_-_210738378 0.08 ENSRNOT00000025746
glutathione S-transferase, mu 6
chr13_+_79886832 0.08 ENSRNOT00000077069
ENSRNOT00000035558
ENSRNOT00000076417
phosphatidylinositol glycan anchor biosynthesis, class C
chr8_+_117920944 0.08 ENSRNOT00000028125
NME/NM23 nucleoside diphosphate kinase 6
chr4_+_155313671 0.08 ENSRNOT00000020812
microfibrillar associated protein 5
chrX_-_104726816 0.07 ENSRNOT00000005165
tetraspanin 6
chr7_-_125407806 0.07 ENSRNOT00000084666
similar to mKIAA1644 protein
chr2_+_189581644 0.07 ENSRNOT00000092112
RAB13, member RAS oncogene family
chr9_+_40975836 0.07 ENSRNOT00000084470
protein tyrosine phosphatase, non-receptor type 18
chr7_-_11699436 0.07 ENSRNOT00000049221
ENSRNOT00000066037
transmembrane protease, serine 9
chr3_+_2642531 0.07 ENSRNOT00000081798
fucosyltransferase 7
chr1_-_226924244 0.07 ENSRNOT00000028971
transmembrane protein 132A
chrX_+_63343546 0.07 ENSRNOT00000076315
kelch-like family member 15
chr13_-_110257367 0.07 ENSRNOT00000005576
denticleless E3 ubiquitin protein ligase homolog
chr10_+_108395860 0.07 ENSRNOT00000075796
glucosidase, alpha, acid
chrX_-_105568343 0.07 ENSRNOT00000029807
armadillo repeat containing, X-linked 6
chr6_-_43448280 0.07 ENSRNOT00000081110
ADAM metallopeptidase domain 17
chr20_-_3374344 0.07 ENSRNOT00000082999
protein phosphatase 1, regulatory subunit 18
chr1_-_79930263 0.07 ENSRNOT00000019219
forkhead box A3
chr3_+_103747654 0.07 ENSRNOT00000006887
NOP10 ribonucleoprotein
chr1_-_77865870 0.07 ENSRNOT00000017353
EH-domain containing 2
chr9_-_71313940 0.07 ENSRNOT00000019670
methyltransferase like 21A
chr1_+_222519615 0.07 ENSRNOT00000083585
REST corepressor 2
chr20_+_6869767 0.07 ENSRNOT00000000631
ENSRNOT00000086330
ENSRNOT00000093188
ENSRNOT00000093736
similar to GI:13385412-like protein splice form I
chr10_+_92289107 0.06 ENSRNOT00000050070
microtubule-associated protein tau
chr20_+_3935529 0.06 ENSRNOT00000072458
class II histocompatibility antigen, M alpha chain
chr12_+_2228670 0.06 ENSRNOT00000001327
trafficking protein particle complex 5
chr19_+_46761570 0.06 ENSRNOT00000058779
WW domain-containing oxidoreductase
chr17_+_9631925 0.06 ENSRNOT00000018114
DEAD-box helicase 41
chr19_+_38397466 0.06 ENSRNOT00000034386
NIN1/PSMD8 binding protein 1 homolog
chr1_+_101213788 0.06 ENSRNOT00000090838
TEA domain transcription factor 2
chr15_+_45712821 0.06 ENSRNOT00000083381
ENSRNOT00000045833
family with sequence similarity 124 member A
chr10_-_104358253 0.06 ENSRNOT00000005942
cask-interacting protein 2
chr1_+_40389638 0.06 ENSRNOT00000021471
pleckstrin homology and RhoGEF domain containing G1
chr6_+_51662224 0.06 ENSRNOT00000060006
coiled-coil domain containing 71-like
chr7_+_94777702 0.06 ENSRNOT00000049001
H3 histone, family 3C
chr10_+_11877903 0.06 ENSRNOT00000076532
ENSRNOT00000075890
RGD1561796
chr20_+_28920616 0.06 ENSRNOT00000070897
prolyl 4-hydroxylase subunit alpha 1
chr13_-_99101208 0.06 ENSRNOT00000004329
H3 histone family member 3A
chr6_-_29483460 0.06 ENSRNOT00000007160
kelch-like family member 29
chr7_-_23843505 0.06 ENSRNOT00000006366
ENSRNOT00000077577
F-box protein 7
chr1_-_198298076 0.06 ENSRNOT00000027033
INO80 complex subunit E
chr19_+_10119253 0.06 ENSRNOT00000017971
zinc finger protein 319
chr18_+_29993361 0.06 ENSRNOT00000075810
protocadherin alpha 4
chr10_+_35392762 0.06 ENSRNOT00000059277
RasGEF domain family, member 1C
chr4_-_171176581 0.06 ENSRNOT00000030850
RAS-like, estrogen-regulated, growth-inhibitor
chr1_-_101131413 0.06 ENSRNOT00000093729
fms-related tyrosine kinase 3 ligand
chr9_+_11031841 0.06 ENSRNOT00000074695
SH3 domain-containing GRB2-like 1
chr15_+_19429508 0.06 ENSRNOT00000047113
ribosomal protein S10-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Ctcfl_Ctcf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0035711 granuloma formation(GO:0002432) T-helper 1 cell activation(GO:0035711)
0.1 0.3 GO:2000424 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.2 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.2 GO:1903544 positive regulation of bicellular tight junction assembly(GO:1903348) response to butyrate(GO:1903544)
0.1 0.3 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1 0.3 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.4 GO:0002339 B cell selection(GO:0002339) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.2 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.3 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0002489 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0002003 angiotensin maturation(GO:0002003) renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.3 GO:0035934 corticosterone secretion(GO:0035934)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.2 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.0 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:1905218 cellular response to astaxanthin(GO:1905218)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.0 0.1 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.0 0.1 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.0 0.1 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.0 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.1 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:0006527 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.0 0.0 GO:0015942 formate metabolic process(GO:0015942)
0.0 0.1 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.3 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0033290 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290) eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.0 GO:0045134 uridine-diphosphatase activity(GO:0045134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation