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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Clock

Z-value: 0.28

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Transcription factors associated with Clock

Gene Symbol Gene ID Gene Info
ENSRNOG00000002175 clock circadian regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Clockrn6_v1_chr14_+_34455934_34455934-0.721.7e-01Click!

Activity profile of Clock motif

Sorted Z-values of Clock motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_221773254 0.08 ENSRNOT00000028646
RAS guanyl releasing protein 2
chr1_-_265506046 0.07 ENSRNOT00000023963
nucleophosmin/nucleoplasmin, 3
chr8_-_130127392 0.07 ENSRNOT00000026159
cholecystokinin
chr5_+_165405168 0.07 ENSRNOT00000014934
spermidine synthase
chr8_-_62386264 0.06 ENSRNOT00000026165
complexin 3
chr6_+_42852683 0.05 ENSRNOT00000079185
ornithine decarboxylase 1
chr16_+_49462889 0.05 ENSRNOT00000039909
ankyrin repeat domain 37
chr7_-_82059247 0.05 ENSRNOT00000087177
R-spondin 2
chr10_-_88667345 0.05 ENSRNOT00000025518
potassium voltage-gated channel subfamily H member 4
chr2_+_127538659 0.05 ENSRNOT00000093483
ENSRNOT00000058476
solute carrier family 25 member 31
chr3_+_14588870 0.05 ENSRNOT00000071712
spermidine synthase-like
chr8_-_52814188 0.04 ENSRNOT00000087265
ENSRNOT00000047633
RNA exonuclease 2
chr5_+_74649765 0.04 ENSRNOT00000075952
paralemmin 2
chr10_-_83898527 0.04 ENSRNOT00000009815
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr5_+_152680407 0.04 ENSRNOT00000076864
stathmin 1
chr6_-_114488880 0.04 ENSRNOT00000087560

chr18_+_72550219 0.04 ENSRNOT00000046847
SMAD family member 2
chr2_+_187893875 0.04 ENSRNOT00000093014
mex-3 RNA binding family member A
chr1_-_198120061 0.04 ENSRNOT00000026231
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr2_-_187160373 0.03 ENSRNOT00000018961
neurotrophic receptor tyrosine kinase 1
chr6_+_33786627 0.03 ENSRNOT00000008359
pumilio RNA-binding family member 2
chr20_-_43108198 0.03 ENSRNOT00000000742
histone deacetylase 2
chr1_+_198120099 0.03 ENSRNOT00000073652
bolA family member 2
chr12_-_3924415 0.03 ENSRNOT00000067752

chr9_+_17817721 0.03 ENSRNOT00000086986
ENSRNOT00000026920
heat shock protein 90 alpha family class B member 1
chr19_+_58565576 0.03 ENSRNOT00000026965
nucleoside-triphosphatase, cancer-related
chr6_+_43829945 0.03 ENSRNOT00000086548
Kruppel-like factor 11
chr5_+_140979435 0.03 ENSRNOT00000056592
poly(A) binding protein, cytoplasmic 4
chr10_+_89236256 0.03 ENSRNOT00000027957
proteasome activator subunit 3
chr3_+_71020534 0.02 ENSRNOT00000007276
zinc finger CCCH-type containing 15
chr11_-_83985385 0.02 ENSRNOT00000002334
endothelin-converting enzyme 2-like
chr5_-_147953093 0.02 ENSRNOT00000075270
KH RNA binding domain containing, signal transduction associated 1
chr1_-_163328591 0.02 ENSRNOT00000034843
tsukushi, small leucine rich proteoglycan
chr2_-_148891900 0.02 ENSRNOT00000018488
siah E3 ubiquitin protein ligase 2
chr10_+_54246250 0.02 ENSRNOT00000004880
recoverin
chr3_+_113415774 0.02 ENSRNOT00000056151
small EDRK-rich factor 2
chr8_-_115140080 0.02 ENSRNOT00000015851
aminoacylase 1
chr9_+_66495832 0.02 ENSRNOT00000022676
ENSRNOT00000091283
NOP58 ribonucleoprotein
chr7_-_27240528 0.02 ENSRNOT00000029435
ENSRNOT00000079731
heat shock protein 90 beta family member 1
chr13_+_100129761 0.02 ENSRNOT00000038340
eukaryotic translation initiation factor 3, subunit E-like 1
chr4_-_78879294 0.02 ENSRNOT00000084543
insulin-like growth factor 2 mRNA binding protein 3
chr11_-_60613718 0.02 ENSRNOT00000002906
autophagy related 3
chr3_+_61685619 0.02 ENSRNOT00000002140
homeo box D1
chrX_+_16946207 0.01 ENSRNOT00000003981
similar to cysteine-rich protein 2
chr10_-_57618527 0.01 ENSRNOT00000037517
complement C1q binding protein
chr13_-_90814119 0.01 ENSRNOT00000011208
transgelin 2
chr18_+_36829062 0.01 ENSRNOT00000025467
ENSRNOT00000086979
transcription elongation regulator 1
chr10_-_11760620 0.01 ENSRNOT00000009283
deoxyribonuclease 1
chr19_+_53055745 0.01 ENSRNOT00000074430
forkhead box L1
chr6_-_55001464 0.01 ENSRNOT00000006618
aryl hydrocarbon receptor
chr10_-_40375605 0.01 ENSRNOT00000014464
annexin A6
chr10_+_83476107 0.01 ENSRNOT00000075733
prohibitin
chr10_+_57057608 0.01 ENSRNOT00000085810
ENSRNOT00000026335
mediator complex subunit 11
chr7_+_77966722 0.01 ENSRNOT00000006142
collagen triple helix repeat containing 1
chr10_+_82352390 0.01 ENSRNOT00000004941
leucine rich repeat containing 59
chr4_-_77489535 0.01 ENSRNOT00000008728
protein disulfide isomerase family A, member 4
chr8_+_44047592 0.01 ENSRNOT00000085084
zinc finger protein 202
chr2_-_197991198 0.01 ENSRNOT00000056322
circadian associated repressor of transcription
chr3_+_122803772 0.01 ENSRNOT00000009564
NOP56 ribonucleoprotein
chr11_+_47090245 0.01 ENSRNOT00000060645

chr2_-_197991574 0.01 ENSRNOT00000085632
circadian associated repressor of transcription
chr3_-_159802952 0.01 ENSRNOT00000011610
oxidative stress responsive serine-rich 1
chr10_-_32471454 0.01 ENSRNOT00000003224
sarcoglycan, delta
chr1_+_127802978 0.01 ENSRNOT00000055877
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr14_+_36216002 0.01 ENSRNOT00000038506
sec1 family domain containing 2
chr9_-_16979044 0.01 ENSRNOT00000073191
ENSRNOT00000025335
zinc finger protein 318
chr12_+_21981755 0.01 ENSRNOT00000001871
7SK snRNA methylphosphate capping enzyme-like
chr9_-_61690956 0.01 ENSRNOT00000066589
heat shock protein family D member 1
chr6_+_80220547 0.01 ENSRNOT00000086221
ENSRNOT00000077435
ENSRNOT00000059318
ENSRNOT00000089010
melanoma inhibitory activity 2
chr10_+_91710495 0.01 ENSRNOT00000033276
reprimo-like
chr14_-_33580566 0.01 ENSRNOT00000063942
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr3_-_122947075 0.01 ENSRNOT00000082369
PC-esterase domain containing 1A
chr10_+_46783979 0.01 ENSRNOT00000005237
GID complex subunit 4
chr16_+_7103998 0.00 ENSRNOT00000016581
polybromo 1
chr5_-_58124681 0.00 ENSRNOT00000019795
sigma non-opioid intracellular receptor 1
chr3_-_163935617 0.00 ENSRNOT00000074023
potassium voltage-gated channel subfamily B member 1
chr5_+_60250546 0.00 ENSRNOT00000017707
zinc finger CCHC-type containing 7
chr8_+_22050222 0.00 ENSRNOT00000028096
intercellular adhesion molecule 5
chr10_-_57005272 0.00 ENSRNOT00000026102
proline, glutamate and leucine rich protein 1
chr10_-_37455022 0.00 ENSRNOT00000016742
ubiquitin-conjugating enzyme E2 B
chr14_-_100372760 0.00 ENSRNOT00000007824
partner of NOB1 homolog
chr3_+_11424099 0.00 ENSRNOT00000019184
prostaglandin E synthase 2
chr9_+_15393330 0.00 ENSRNOT00000075630
bystin-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Clock

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.0 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.1 GO:0033387 putrescine biosynthetic process(GO:0009446) putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.0 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0033557 Slx1-Slx4 complex(GO:0033557)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.0 0.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)