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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Cebpe
Z-value: 1.11
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Transcription factors associated with Cebpe
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Cebpe | rn6_v1_chr15_-_33358138_33358138 | -0.68 | 2.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_44442875 Show fit | 0.49 |
ENSRNOT00000017939
|
gonadotropin releasing hormone 1 |
|
| chr20_-_4070721 Show fit | 0.33 |
ENSRNOT00000000523
|
RT1 class II, locus Ba |
|
| chr10_+_64737022 Show fit | 0.32 |
ENSRNOT00000017071
ENSRNOT00000093232 ENSRNOT00000017042 ENSRNOT00000093244 |
galectin 9 |
|
| chr4_-_23135354 Show fit | 0.31 |
ENSRNOT00000011432
|
STEAP4 metalloreductase |
|
| chr18_+_55505993 Show fit | 0.31 |
ENSRNOT00000043736
|
similar to interferon-inducible GTPase |
|
| chr5_+_74649765 Show fit | 0.30 |
ENSRNOT00000075952
|
paralemmin 2 |
|
| chr14_-_33031282 Show fit | 0.30 |
ENSRNOT00000043244
|
60S ribosomal protein L39 |
|
| chr18_-_36513317 Show fit | 0.28 |
ENSRNOT00000025453
|
PLAC8-like 1 |
|
| chr2_+_243550627 Show fit | 0.28 |
ENSRNOT00000085067
ENSRNOT00000083682 |
alcohol dehydrogenase 1 (class I) |
|
| chr1_+_252409268 Show fit | 0.27 |
ENSRNOT00000026219
|
lipase, family member M |
Network of associatons between targets according to the STRING database.
First level regulatory network of Cebpe
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.1 | 0.5 | GO:2001190 | positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190) |
| 0.1 | 0.5 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
| 0.0 | 0.5 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.0 | 0.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 0.3 | GO:0071623 | negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) |
| 0.1 | 0.3 | GO:0006713 | glucocorticoid catabolic process(GO:0006713) |
| 0.1 | 0.3 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.1 | 0.3 | GO:0070839 | divalent metal ion export(GO:0070839) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 0.5 | GO:1990005 | granular vesicle(GO:1990005) |
| 0.0 | 0.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.4 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 0.3 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.1 | 0.3 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 0.0 | 0.3 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.3 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.0 | 0.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.3 | GO:0097228 | sperm principal piece(GO:0097228) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 0.6 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.1 | 0.4 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.0 | 0.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.4 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.3 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.1 | 0.3 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.0 | 0.3 | GO:0048030 | disaccharide binding(GO:0048030) |
| 0.0 | 0.3 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.4 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.2 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 0.4 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.4 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.4 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 0.3 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 0.3 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | Genes involved in Synthesis of bile acids and bile salts |
| 0.0 | 0.2 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.2 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.0 | 0.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |