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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Cebpb

Z-value: 0.41

Motif logo

Transcription factors associated with Cebpb

Gene Symbol Gene ID Gene Info
ENSRNOG00000057347 CCAAT/enhancer binding protein beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cebpbrn6_v1_chr3_+_164424515_1644245150.847.5e-02Click!

Activity profile of Cebpb motif

Sorted Z-values of Cebpb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_70871066 0.32 ENSRNOT00000015139
C-C motif chemokine ligand 3
chr11_+_30904733 0.20 ENSRNOT00000036027
melanocortin 2 receptor accessory protein
chr16_-_6675746 0.20 ENSRNOT00000025858
protein kinase C, delta
chr3_-_11417546 0.18 ENSRNOT00000018776
lipocalin 2
chrX_+_33443186 0.18 ENSRNOT00000005622
S100 calcium binding protein G
chr19_+_14508616 0.18 ENSRNOT00000019192
heme oxygenase 1
chr3_-_147819571 0.17 ENSRNOT00000009840
tribbles pseudokinase 3
chr8_-_117932518 0.16 ENSRNOT00000028130
cathelicidin antimicrobial peptide
chr16_-_75309176 0.16 ENSRNOT00000018427
defensin beta 1
chr16_-_14300951 0.15 ENSRNOT00000017038
retinal G protein coupled receptor
chr16_+_61954809 0.13 ENSRNOT00000068011
RNA binding protein with multiple splicing
chr2_+_227657983 0.12 ENSRNOT00000021116
protease, serine 12
chr1_+_91152635 0.12 ENSRNOT00000073438
dermokine-like
chr14_-_44375804 0.12 ENSRNOT00000042825
ribosomal protein P2-like
chr11_-_34142753 0.11 ENSRNOT00000002297
claudin 14
chr9_-_78969013 0.11 ENSRNOT00000019772
ENSRNOT00000057585
fibronectin 1
chr12_+_38160464 0.11 ENSRNOT00000032249
hydroxycarboxylic acid receptor 2
chr16_+_61954590 0.11 ENSRNOT00000017883
RNA binding protein with multiple splicing
chr18_+_32594958 0.10 ENSRNOT00000018511
sprouty RTK signaling antagonist 4
chr2_-_190100276 0.10 ENSRNOT00000015351
S100 calcium binding protein A9
chr20_-_45260119 0.10 ENSRNOT00000000718
solute carrier family 16 member 10
chr4_+_33638709 0.09 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr9_+_74124016 0.09 ENSRNOT00000019023
carbamoyl-phosphate synthase 1
chr10_-_108196217 0.08 ENSRNOT00000075440
chromobox 4
chr4_-_28953067 0.08 ENSRNOT00000013989
tissue factor pathway inhibitor 2
chr4_-_82173207 0.08 ENSRNOT00000074167
homeo box A5
chr10_-_59112788 0.08 ENSRNOT00000041886
SPNS sphingolipid transporter 3
chr19_-_52499433 0.07 ENSRNOT00000021954
coactosin-like F-actin binding protein 1
chr18_-_29562153 0.07 ENSRNOT00000023977
CD14 molecule
chr20_+_6102277 0.07 ENSRNOT00000033064
patatin-like phospholipase domain containing 1
chr3_+_151285249 0.07 ENSRNOT00000055254
protein C receptor
chr6_-_125723944 0.07 ENSRNOT00000007004
fibulin 5
chr10_-_90049112 0.07 ENSRNOT00000028323
peptide YY (mapped)
chr7_-_12326392 0.07 ENSRNOT00000039728
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr10_-_20622600 0.07 ENSRNOT00000020554
fibrillarin-like 1
chrX_+_111396995 0.07 ENSRNOT00000087634
PIH1 domain containing 3
chr10_-_87407634 0.07 ENSRNOT00000016657
keratin 23
chr8_-_111721303 0.06 ENSRNOT00000045628
ENSRNOT00000012725
transferrin
chr14_-_8548310 0.06 ENSRNOT00000092436
Rho GTPase activating protein 24
chr4_-_38240848 0.06 ENSRNOT00000007567
NADH:ubiquinone oxidoreductase subunit A4
chr6_+_24163026 0.06 ENSRNOT00000061284
limb bud and heart development
chr19_-_11057254 0.06 ENSRNOT00000025559
homocysteine inducible ER protein with ubiquitin like domain 1
chr10_+_55940533 0.06 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr8_+_22856539 0.06 ENSRNOT00000015381
angiopoietin-like 8
chr6_-_125723732 0.06 ENSRNOT00000084815
fibulin 5
chr7_-_12640232 0.06 ENSRNOT00000014981
elastase, neutrophil expressed
chr8_+_116857684 0.06 ENSRNOT00000026711
macrophage stimulating 1
chr6_+_56846789 0.06 ENSRNOT00000032108
alkylglycerol monooxygenase
chr4_+_147333056 0.05 ENSRNOT00000012137
peroxisome proliferator-activated receptor gamma
chr5_+_145079803 0.05 ENSRNOT00000084202
splicing factor proline and glutamine rich
chr1_+_256786124 0.05 ENSRNOT00000034563
free fatty acid receptor 4
chr4_+_38240728 0.05 ENSRNOT00000047029
PHD finger protein 14
chr4_-_35730599 0.05 ENSRNOT00000051149
ribosomal protein S4, X-linked
chr9_+_61655963 0.05 ENSRNOT00000040461
coenzyme Q10B
chr5_-_137372993 0.05 ENSRNOT00000092823
transmembrane protein 125
chr5_+_168078748 0.05 ENSRNOT00000024798
urotensin 2
chr20_+_3176107 0.05 ENSRNOT00000001036
RT1 class Ib, locus S3
chr3_+_58164931 0.05 ENSRNOT00000002078
distal-less homeobox 1
chr7_+_114997103 0.05 ENSRNOT00000010224
protein tyrosine phosphatase type IVA, member 3
chr3_+_111160205 0.05 ENSRNOT00000019392
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
chr5_+_128450680 0.05 ENSRNOT00000010700
thioredoxin domain containing 12
chr10_-_62254287 0.05 ENSRNOT00000004313
serpin family F member 1
chr1_-_225014538 0.04 ENSRNOT00000026376
tetratricopeptide repeat domain 9C
chr1_+_84256159 0.04 ENSRNOT00000031026
biliverdin reductase B
chr7_-_27240528 0.04 ENSRNOT00000029435
ENSRNOT00000079731
heat shock protein 90 beta family member 1
chr1_-_156327352 0.04 ENSRNOT00000074282
coiled-coil domain-containing protein 89-like
chr14_+_84306466 0.04 ENSRNOT00000006116
SEC14-like lipid binding 4
chr1_-_100537377 0.04 ENSRNOT00000026599
Spi-B transcription factor
chr2_+_187275120 0.04 ENSRNOT00000017234
hepatoma-derived growth factor
chr20_+_7908304 0.04 ENSRNOT00000000603
ribosomal protein L10A
chr1_-_101596822 0.04 ENSRNOT00000028490
fibroblast growth factor 21
chr7_+_70580198 0.04 ENSRNOT00000083472
ENSRNOT00000008941
DNA-damage inducible transcript 3
chrX_+_143097525 0.04 ENSRNOT00000004559
coagulation factor IX
chr9_-_45558993 0.04 ENSRNOT00000087866
ENSRNOT00000017714
carbohydrate sulfotransferase 10
chr20_+_7821755 0.04 ENSRNOT00000083109
peroxisome proliferator-activated receptor delta
chr7_-_116936674 0.04 ENSRNOT00000029456
eukaryotic translation elongation factor 1 delta
chrX_-_138118696 0.04 ENSRNOT00000084130
FERM domain containing 7
chr18_+_16590197 0.04 ENSRNOT00000066583
molybdenum cofactor sulfurase
chr4_+_100166863 0.04 ENSRNOT00000014505
surfactant protein B
chr20_-_25826658 0.04 ENSRNOT00000057950
ENSRNOT00000084660
catenin alpha 3
chr3_+_11921715 0.04 ENSRNOT00000021689
family with sequence similarity 129, member B
chr20_-_32133431 0.04 ENSRNOT00000000443
serglycin
chr3_+_117421604 0.04 ENSRNOT00000008860
ENSRNOT00000008857
solute carrier family 12 member 1
chr2_+_181987217 0.04 ENSRNOT00000034521
fibrinogen gamma chain
chr10_+_98706960 0.03 ENSRNOT00000006217
mitogen-activated protein kinase kinase 6
chr1_-_22661377 0.03 ENSRNOT00000021896
vanin 3
chr5_+_144031402 0.03 ENSRNOT00000011694
colony stimulating factor 3 receptor
chr11_-_60546997 0.03 ENSRNOT00000083124
ENSRNOT00000050092
B and T lymphocyte associated
chr15_-_49467174 0.03 ENSRNOT00000019209
ADAM metallopeptidase domain 7
chr20_+_4517307 0.03 ENSRNOT00000000483
decapping exoribonuclease
chr13_+_48427038 0.03 ENSRNOT00000009241
cathepsin E
chr8_-_53816447 0.03 ENSRNOT00000011454
tetratricopeptide repeat domain 12
chr3_+_102925471 0.03 ENSRNOT00000040364
olfactory receptor 772
chr14_+_45062662 0.03 ENSRNOT00000059124
toll-like receptor 10
chr16_+_85305493 0.03 ENSRNOT00000088012

chr1_-_101426852 0.03 ENSRNOT00000028217
RuvB-like AAA ATPase 2
chr2_-_139528162 0.03 ENSRNOT00000014317
solute carrier family 7 member 11
chr18_-_60002529 0.03 ENSRNOT00000081014
ENSRNOT00000024264
ENSRNOT00000059162
asparaginyl-tRNA synthetase
chr1_+_99718907 0.03 ENSRNOT00000048240
kallikrein related-peptidase 10
chr8_-_133002201 0.03 ENSRNOT00000008772
C-C motif chemokine receptor 1
chr7_+_2504695 0.03 ENSRNOT00000003965
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr19_-_17045349 0.03 ENSRNOT00000086829
FTO, alpha-ketoglutarate dependent dioxygenase
chr7_-_14303055 0.03 ENSRNOT00000008963
bromodomain containing 4
chr2_+_55775274 0.03 ENSRNOT00000018545
complement C9
chr17_+_15762030 0.02 ENSRNOT00000089310
FYVE, RhoGEF and PH domain containing 3
chr20_+_22913694 0.02 ENSRNOT00000067920
receptor accessory protein 3
chr7_-_14302552 0.02 ENSRNOT00000091368
bromodomain containing 4
chr1_-_93949187 0.02 ENSRNOT00000018956
zinc finger protein 536
chr1_-_256813711 0.02 ENSRNOT00000021055
retinol binding protein 4
chr15_-_33527031 0.02 ENSRNOT00000019979
homeobox and leucine zipper encoding
chr10_+_56710464 0.02 ENSRNOT00000065370
ENSRNOT00000064064
asialoglycoprotein receptor 2
chr5_+_151181559 0.02 ENSRNOT00000085674
FGR proto-oncogene, Src family tyrosine kinase
chr3_+_97349454 0.02 ENSRNOT00000089524
doublecortin domain containing 5
chr4_-_82258765 0.02 ENSRNOT00000008523
homeo box A5
chr1_+_154606490 0.02 ENSRNOT00000024095
coiled-coil domain containing 89
chr1_+_101427195 0.02 ENSRNOT00000028271
glycogen synthase 1
chr7_-_101140308 0.02 ENSRNOT00000006279
family with sequence similarity 84, member B
chr16_+_18690246 0.02 ENSRNOT00000081484
methionine adenosyltransferase 1A
chr15_+_28018040 0.02 ENSRNOT00000041495
ribonuclease A family member 4
chr1_+_89215266 0.02 ENSRNOT00000093612
ENSRNOT00000084799
dermokine
chr3_-_35797804 0.02 ENSRNOT00000083776
methylmalonic aciduria and homocystinuria, cblD type
chr2_-_147693082 0.02 ENSRNOT00000022507
WW domain containing transcription regulator 1
chr14_-_35581031 0.02 ENSRNOT00000003077
platelet derived growth factor receptor alpha
chr3_+_112531703 0.02 ENSRNOT00000041727
protein CASC5-like
chr3_+_170399302 0.02 ENSRNOT00000035245
Cas scaffolding protein family member 4
chr12_-_47095438 0.02 ENSRNOT00000001546
coenzyme Q5, methyltransferase
chr9_+_95233957 0.02 ENSRNOT00000071003
UDP glucuronosyltransferase family 1 member A5
chr19_+_25239674 0.02 ENSRNOT00000037453
podocan-like 1
chr19_-_43215281 0.02 ENSRNOT00000025052
alanyl-tRNA synthetase
chr3_-_101474890 0.02 ENSRNOT00000091869
gamma-butyrobetaine hydroxylase 1
chr14_-_100184192 0.01 ENSRNOT00000007044
pleckstrin
chr7_-_70829815 0.01 ENSRNOT00000011082
serine hydroxymethyltransferase 2
chr13_+_52887649 0.01 ENSRNOT00000048033
achaete-scute family bHLH transcription factor 5
chr1_+_137799185 0.01 ENSRNOT00000083590
ENSRNOT00000092778
ATP/GTP binding protein-like 1
chr20_-_45259928 0.01 ENSRNOT00000087226
solute carrier family 16 member 10
chr8_+_118013612 0.01 ENSRNOT00000056166
microtubule-associated protein 4
chr10_-_109821807 0.01 ENSRNOT00000054949
pyrroline-5-carboxylate reductase 1
chr11_-_60547201 0.01 ENSRNOT00000093151
B and T lymphocyte associated
chr18_+_16590408 0.01 ENSRNOT00000093715
molybdenum cofactor sulfurase
chr1_+_89202527 0.01 ENSRNOT00000028526
suprabasin
chr7_-_76294663 0.01 ENSRNOT00000064513
neurocalcin delta
chr4_+_114776797 0.01 ENSRNOT00000089635
polycomb group RING finger protein 1
chr3_+_154786215 0.01 ENSRNOT00000019787
lipopolysaccharide binding protein
chr19_-_43215077 0.01 ENSRNOT00000082151
alanyl-tRNA synthetase
chr6_+_10533151 0.01 ENSRNOT00000020822
ras homolog family member Q
chr8_+_116657371 0.01 ENSRNOT00000024966
MON1 homolog A, secretory trafficking associated
chr19_+_15081158 0.01 ENSRNOT00000074070
carboxylesterase 1F
chr19_+_15081590 0.01 ENSRNOT00000024187
carboxylesterase 1F
chr10_-_107386072 0.01 ENSRNOT00000004290
TIMP metallopeptidase inhibitor 2
chr13_-_111972603 0.01 ENSRNOT00000007870
hydroxysteroid 11-beta dehydrogenase 1
chr1_-_263269762 0.01 ENSRNOT00000022309
glutamic-oxaloacetic transaminase 1
chr1_+_276240703 0.01 ENSRNOT00000022126
acyl-CoA synthetase long-chain family member 5
chr15_+_2734068 0.01 ENSRNOT00000017663
dual specificity phosphatase 13
chr20_-_2103864 0.01 ENSRNOT00000001014
ring finger protein 39
chr1_-_219168177 0.00 ENSRNOT00000023789
aldehyde dehydrogenase 3 family, member B1
chr15_+_2527343 0.00 ENSRNOT00000089013
dual specificity phosphatase 13
chr9_+_46962288 0.00 ENSRNOT00000082146
interleukin 1 receptor type 1
chr8_+_5768811 0.00 ENSRNOT00000013936
matrix metallopeptidase 8
chr7_+_83113672 0.00 ENSRNOT00000006783
thyrotropin releasing hormone receptor
chr3_-_168111920 0.00 ENSRNOT00000046011
cytochrome P450, family 24, subfamily a, polypeptide 1
chr10_-_82117109 0.00 ENSRNOT00000079711
ATP binding cassette subfamily C member 3
chr18_-_15688284 0.00 ENSRNOT00000091816
desmoglein 3
chr10_-_82116621 0.00 ENSRNOT00000003977
ENSRNOT00000051497
ENSRNOT00000085451
ATP binding cassette subfamily C member 3
chr10_-_72188164 0.00 ENSRNOT00000085728
ENSRNOT00000042506
gametogenetin binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.2 GO:0034395 heme oxidation(GO:0006788) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:2001201 calcium-independent cell-matrix adhesion(GO:0007161) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.0 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0032639 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0050828 regulation of liquid surface tension(GO:0050828)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.0 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0032398 MHC class Ib protein complex(GO:0032398)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0042581 specific granule(GO:0042581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.2 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173) thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.0 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins