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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Cebpb
Z-value: 0.41
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Transcription factors associated with Cebpb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Cebpb | rn6_v1_chr3_+_164424515_164424515 | 0.84 | 7.5e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_70871066 Show fit | 0.32 |
ENSRNOT00000015139
|
C-C motif chemokine ligand 3 |
|
| chr11_+_30904733 Show fit | 0.20 |
ENSRNOT00000036027
|
melanocortin 2 receptor accessory protein |
|
| chr16_-_6675746 Show fit | 0.20 |
ENSRNOT00000025858
|
protein kinase C, delta |
|
| chr3_-_11417546 Show fit | 0.18 |
ENSRNOT00000018776
|
lipocalin 2 |
|
| chrX_+_33443186 Show fit | 0.18 |
ENSRNOT00000005622
|
S100 calcium binding protein G |
|
| chr19_+_14508616 Show fit | 0.18 |
ENSRNOT00000019192
|
heme oxygenase 1 |
|
| chr3_-_147819571 Show fit | 0.17 |
ENSRNOT00000009840
|
tribbles pseudokinase 3 |
|
| chr8_-_117932518 Show fit | 0.16 |
ENSRNOT00000028130
|
cathelicidin antimicrobial peptide |
|
| chr16_-_75309176 Show fit | 0.16 |
ENSRNOT00000018427
|
defensin beta 1 |
|
| chr16_-_14300951 Show fit | 0.15 |
ENSRNOT00000017038
|
retinal G protein coupled receptor |
Network of associatons between targets according to the STRING database.
First level regulatory network of Cebpb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 0.1 | 0.2 | GO:0060697 | positive regulation of phospholipid catabolic process(GO:0060697) |
| 0.1 | 0.2 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.1 | 0.2 | GO:0034395 | heme oxidation(GO:0006788) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) |
| 0.1 | 0.2 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.0 | 0.2 | GO:0071224 | cellular response to peptidoglycan(GO:0071224) |
| 0.0 | 0.2 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.0 | 0.2 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.0 | 0.1 | GO:2001201 | calcium-independent cell-matrix adhesion(GO:0007161) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of transforming growth factor-beta secretion(GO:2001201) |
| 0.0 | 0.1 | GO:1903575 | cornified envelope assembly(GO:1903575) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 0.2 | GO:0042581 | specific granule(GO:0042581) |
| 0.0 | 0.1 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.0 | 0.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.1 | GO:0032398 | MHC class Ib protein complex(GO:0032398) |
| 0.0 | 0.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 0.1 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.0 | GO:1990622 | CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622) |
| 0.0 | 0.0 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 0.1 | 0.2 | GO:0031783 | corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) |
| 0.1 | 0.2 | GO:0070976 | TIR domain binding(GO:0070976) |
| 0.1 | 0.2 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.1 | 0.2 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.0 | 0.2 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 0.2 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.0 | 0.1 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.0 | 0.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.0 | 0.1 | GO:0045340 | mercury ion binding(GO:0045340) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.2 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 0.2 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.2 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.1 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |