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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Cebpa_Cebpg

Z-value: 0.39

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Transcription factors associated with Cebpa_Cebpg

Gene Symbol Gene ID Gene Info
ENSRNOG00000010918 CCAAT/enhancer binding protein alpha
ENSRNOG00000021144 CCAAT/enhancer binding protein gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cebparn6_v1_chr1_+_91363492_913634920.692.0e-01Click!
Cebpgrn6_v1_chr1_-_91296656_91296656-0.266.7e-01Click!

Activity profile of Cebpa_Cebpg motif

Sorted Z-values of Cebpa_Cebpg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_227657983 0.20 ENSRNOT00000021116
protease, serine 12
chr2_+_158097843 0.18 ENSRNOT00000016541
pentraxin 3
chr1_-_168972725 0.17 ENSRNOT00000090422
hemoglobin subunit beta
chr1_+_91152635 0.17 ENSRNOT00000073438
dermokine-like
chr1_+_168964202 0.15 ENSRNOT00000089102
hemoglobin subunit beta-2-like
chr9_+_23354770 0.10 ENSRNOT00000081459
centromere protein Q
chr11_-_81444375 0.10 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr10_+_55940533 0.09 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr5_+_64294321 0.08 ENSRNOT00000083796
Myb/SANT DNA binding domain containing 3
chrX_-_138118696 0.08 ENSRNOT00000084130
FERM domain containing 7
chr1_-_82279145 0.08 ENSRNOT00000057433
C-X-C motif chemokine ligand 17
chr16_-_14300951 0.08 ENSRNOT00000017038
retinal G protein coupled receptor
chr9_+_9721105 0.08 ENSRNOT00000073042
ENSRNOT00000075494
complement C3
chr7_-_27240528 0.07 ENSRNOT00000029435
ENSRNOT00000079731
heat shock protein 90 beta family member 1
chr13_+_52887649 0.07 ENSRNOT00000048033
achaete-scute family bHLH transcription factor 5
chr4_+_84478839 0.06 ENSRNOT00000012668
proline rich 15
chr1_-_82468064 0.06 ENSRNOT00000038300
transmembrane protein 91
chr10_-_62254287 0.06 ENSRNOT00000004313
serpin family F member 1
chr14_+_84306466 0.05 ENSRNOT00000006116
SEC14-like lipid binding 4
chr14_-_19072677 0.05 ENSRNOT00000060548
similar to alpha-fetoprotein
chr15_+_41643541 0.05 ENSRNOT00000019646
ADP-ribosylation factor like GTPase 11
chr7_-_121232741 0.04 ENSRNOT00000023196
platelet derived growth factor subunit B
chr16_+_61954809 0.04 ENSRNOT00000068011
RNA binding protein with multiple splicing
chr10_-_70871066 0.04 ENSRNOT00000015139
C-C motif chemokine ligand 3
chr16_+_61954590 0.04 ENSRNOT00000017883
RNA binding protein with multiple splicing
chr9_+_71247781 0.04 ENSRNOT00000049654
cAMP responsive element binding protein 1
chr12_-_20486276 0.04 ENSRNOT00000074057
similar to paired immunoglobin-like type 2 receptor beta
chr5_-_135677432 0.04 ENSRNOT00000024393
4-hydroxyphenylpyruvate dioxygenase-like
chr8_+_116754178 0.04 ENSRNOT00000068295
ENSRNOT00000084429
ubiquitin-like modifier activating enzyme 7
chr7_-_144936803 0.04 ENSRNOT00000055279
G protein-coupled receptor 84
chr12_+_38160464 0.04 ENSRNOT00000032249
hydroxycarboxylic acid receptor 2
chr15_+_108956448 0.04 ENSRNOT00000046324

chr20_-_10013190 0.04 ENSRNOT00000084726
ENSRNOT00000089112
radial spoke head 1 homolog
chr2_-_139528162 0.04 ENSRNOT00000014317
solute carrier family 7 member 11
chr2_-_210782746 0.03 ENSRNOT00000025939
ENSRNOT00000081501
glutathione S-transferase, mu 7
chr20_-_32133431 0.03 ENSRNOT00000000443
serglycin
chrX_+_15988604 0.03 ENSRNOT00000003800
ubiquitin specific peptidase 27, X-linked
chr3_+_11921715 0.03 ENSRNOT00000021689
family with sequence similarity 129, member B
chr13_+_85818427 0.03 ENSRNOT00000077227
ENSRNOT00000006117
retinoid X receptor gamma
chr9_+_61655963 0.03 ENSRNOT00000040461
coenzyme Q10B
chr2_+_204932159 0.03 ENSRNOT00000078376
nerve growth factor
chr7_+_58814805 0.03 ENSRNOT00000005909
tetraspanin 8
chr10_-_109821807 0.03 ENSRNOT00000054949
pyrroline-5-carboxylate reductase 1
chr17_+_15749978 0.03 ENSRNOT00000067311
FYVE, RhoGEF and PH domain containing 3
chr13_+_67351087 0.03 ENSRNOT00000003567
prostaglandin-endoperoxide synthase 2
chr14_-_8548310 0.03 ENSRNOT00000092436
Rho GTPase activating protein 24
chr17_-_77527894 0.03 ENSRNOT00000032173
BEN domain containing 7
chr1_+_162320730 0.03 ENSRNOT00000035743
potassium channel tetramerization domain containing 21
chr6_+_128750795 0.03 ENSRNOT00000005781
glutaredoxin 5
chr13_-_88497901 0.03 ENSRNOT00000058560
UDP-N-acetylglucosamine pyrophosphorylase 1
chr3_+_58084606 0.03 ENSRNOT00000084797
methionyl aminopeptidase type 1D (mitochondrial)
chr9_+_74124016 0.03 ENSRNOT00000019023
carbamoyl-phosphate synthase 1
chr20_-_10013559 0.03 ENSRNOT00000091623
radial spoke head 1 homolog
chrX_+_111396995 0.02 ENSRNOT00000087634
PIH1 domain containing 3
chr10_+_96639924 0.02 ENSRNOT00000004756
apolipoprotein H
chrX_+_143097525 0.02 ENSRNOT00000004559
coagulation factor IX
chr15_+_28018040 0.02 ENSRNOT00000041495
ribonuclease A family member 4
chr15_+_57290849 0.02 ENSRNOT00000014909
carboxypeptidase B2
chr9_+_46962288 0.02 ENSRNOT00000082146
interleukin 1 receptor type 1
chr1_-_22661377 0.02 ENSRNOT00000021896
vanin 3
chr12_+_2213705 0.02 ENSRNOT00000031653
mast cell-expressed membrane protein 1
chr17_-_14627937 0.02 ENSRNOT00000020532
osteoglycin
chr3_+_170399302 0.02 ENSRNOT00000035245
Cas scaffolding protein family member 4
chr2_+_234375315 0.02 ENSRNOT00000071270
elongation of very long chain fatty acids protein 6-like
chr13_-_73390393 0.02 ENSRNOT00000067253
ENSRNOT00000093438
LIM homeobox 4
chr12_+_10255416 0.02 ENSRNOT00000092720
G protein-coupled receptor 12
chr8_+_5768811 0.02 ENSRNOT00000013936
matrix metallopeptidase 8
chr5_-_133067245 0.02 ENSRNOT00000033163
selection and upkeep of intraepithelial T cells 10
chr8_-_125645898 0.02 ENSRNOT00000036672
RNA binding motif, single stranded interacting protein 3
chr19_-_49510901 0.02 ENSRNOT00000082929
ENSRNOT00000079969
hypothetical protein LOC687399
chr15_-_28155291 0.02 ENSRNOT00000050820
ribonuclease A family member 2
chr3_-_160573978 0.02 ENSRNOT00000018386
WAP four-disulfide core domain 5
chrX_-_63809861 0.02 ENSRNOT00000009870
MAGE family member D1
chr9_-_78969013 0.01 ENSRNOT00000019772
ENSRNOT00000057585
fibronectin 1
chr2_+_183674522 0.01 ENSRNOT00000014433
transmembrane protein 154
chr18_+_16590197 0.01 ENSRNOT00000066583
molybdenum cofactor sulfurase
chr10_-_59112788 0.01 ENSRNOT00000041886
SPNS sphingolipid transporter 3
chr1_-_191007503 0.01 ENSRNOT00000023262
immunoglobulin superfamily, member 6
chr17_-_18590536 0.01 ENSRNOT00000078992
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr1_-_101596822 0.01 ENSRNOT00000028490
fibroblast growth factor 21
chr10_-_40282881 0.01 ENSRNOT00000013864
TNFAIP3 interacting protein 1
chr3_-_26056818 0.01 ENSRNOT00000044209
LDL receptor related protein 1B
chr11_-_64968437 0.01 ENSRNOT00000059541
COX17 cytochrome c oxidase copper chaperone
chr10_+_56710464 0.01 ENSRNOT00000065370
ENSRNOT00000064064
asialoglycoprotein receptor 2
chr18_-_29562153 0.01 ENSRNOT00000023977
CD14 molecule
chr4_+_33890349 0.01 ENSRNOT00000078680
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr10_-_82116621 0.01 ENSRNOT00000003977
ENSRNOT00000051497
ENSRNOT00000085451
ATP binding cassette subfamily C member 3
chr7_+_60015998 0.01 ENSRNOT00000007309
bestrophin 3
chrX_-_77529374 0.01 ENSRNOT00000078213
fibronectin type III domain containing 3C1
chr2_+_55775274 0.01 ENSRNOT00000018545
complement C9
chr13_+_48426820 0.01 ENSRNOT00000048391
cathepsin E
chr17_-_5463158 0.01 ENSRNOT00000090032
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr2_-_41784929 0.01 ENSRNOT00000086851
RAB3C, member RAS oncogene family
chr7_+_2504695 0.01 ENSRNOT00000003965
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr8_+_116857684 0.01 ENSRNOT00000026711
macrophage stimulating 1
chr14_-_17333588 0.01 ENSRNOT00000077636
protein phosphatase with EF-hand domain 2
chr3_+_2643610 0.01 ENSRNOT00000037169
fucosyltransferase 7
chr1_-_229601032 0.01 ENSRNOT00000016690
ciliary neurotrophic factor
chr3_+_36173002 0.01 ENSRNOT00000038906
LRRGT00012
chr10_-_11935382 0.01 ENSRNOT00000010059
zinc finger protein 174
chr14_+_7113544 0.01 ENSRNOT00000038188
hydroxysteroid (17-beta) dehydrogenase 13
chrX_-_153491837 0.00 ENSRNOT00000089027
eukaryotic translation elongation factor 1 alpha 1-like
chr14_+_45062662 0.00 ENSRNOT00000059124
toll-like receptor 10
chrX_-_1714061 0.00 ENSRNOT00000011592
cyclin-dependent kinase 16
chr1_-_80809769 0.00 ENSRNOT00000045073
carcinoembryonic antigen-related cell adhesion molecule 19
chr1_-_101426852 0.00 ENSRNOT00000028217
RuvB-like AAA ATPase 2
chr3_+_117421604 0.00 ENSRNOT00000008860
ENSRNOT00000008857
solute carrier family 12 member 1
chrX_-_154918095 0.00 ENSRNOT00000085224
elongation factor 1-alpha 1-like
chr13_-_47623849 0.00 ENSRNOT00000006106
interleukin 24
chr11_+_20474483 0.00 ENSRNOT00000082417
ENSRNOT00000002895
neural cell adhesion molecule 2
chrX_+_78991223 0.00 ENSRNOT00000031200
family with sequence similarity 46, member D
chr3_-_14386118 0.00 ENSRNOT00000025649
RAB14, member RAS oncogene family
chr7_+_23854846 0.00 ENSRNOT00000037290
BPI fold containing family C
chr8_+_13861459 0.00 ENSRNOT00000078161
TATA-box binding protein associated factor, RNA polymerase I subunit D
chr8_-_6034142 0.00 ENSRNOT00000014560
baculoviral IAP repeat-containing 2
chr14_+_81837809 0.00 ENSRNOT00000020576
HAUS augmin-like complex, subunit 3
chr10_+_107502695 0.00 ENSRNOT00000038088
endo-beta-N-acetylglucosaminidase
chr10_-_75120247 0.00 ENSRNOT00000011402
lactoperoxidase
chr13_-_82753438 0.00 ENSRNOT00000075948
ATPase Na+/K+ transporting subunit beta 1
chr3_-_43117337 0.00 ENSRNOT00000078001
nuclear receptor subfamily 4, group A, member 2
chr9_+_117583610 0.00 ENSRNOT00000088647
ENSRNOT00000049426
erythrocyte membrane protein band 4.1-like 3
chr11_-_65208837 0.00 ENSRNOT00000003867
glycogen synthase kinase 3 beta
chr9_+_98505259 0.00 ENSRNOT00000051810
erythroferrone
chr18_-_60002529 0.00 ENSRNOT00000081014
ENSRNOT00000024264
ENSRNOT00000059162
asparaginyl-tRNA synthetase
chr4_-_176381477 0.00 ENSRNOT00000048367
solute carrier organic anion transporter family, member 1a6
chr8_+_2604962 0.00 ENSRNOT00000009993
caspase 1
chr4_-_87257667 0.00 ENSRNOT00000083491
5'-nucleotidase, cytosolic IIIA
chr14_-_100184192 0.00 ENSRNOT00000007044
pleckstrin
chrX_+_43881246 0.00 ENSRNOT00000005153
hypothetical LOC317456

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.2 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0072209 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
0.0 0.0 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.0 GO:0055129 L-proline biosynthetic process(GO:0055129)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.0 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME OPSINS Genes involved in Opsins