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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Atf6
Z-value: 0.47
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Transcription factors associated with Atf6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Atf6 | rn6_v1_chr13_-_89242443_89242443 | 0.11 | 8.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_66417741 Show fit | 0.38 |
ENSRNOT00000007662
|
neuronal differentiation 1 |
|
| chr12_-_41671437 Show fit | 0.35 |
ENSRNOT00000001883
|
LIM homeobox 5 |
|
| chr1_-_209641123 Show fit | 0.19 |
ENSRNOT00000021702
|
early B-cell factor 3 |
|
| chr1_+_274245184 Show fit | 0.15 |
ENSRNOT00000018889
|
dual specificity phosphatase 5 |
|
| chr15_+_52241801 Show fit | 0.12 |
ENSRNOT00000082639
|
HR, lysine demethylase and nuclear receptor corepressor |
|
| chr11_+_80255790 Show fit | 0.12 |
ENSRNOT00000002522
|
B-cell CLL/lymphoma 6 |
|
| chr10_+_84167331 Show fit | 0.11 |
ENSRNOT00000010965
|
homeo box B4 |
|
| chr19_+_58823814 Show fit | 0.10 |
ENSRNOT00000027058
ENSRNOT00000088626 |
potassium two pore domain channel subfamily K member 1 |
|
| chr11_-_34142753 Show fit | 0.08 |
ENSRNOT00000002297
|
claudin 14 |
|
| chr4_-_147756294 Show fit | 0.08 |
ENSRNOT00000014537
|
methyl-CpG binding domain 4 DNA glycosylase |
Network of associatons between targets according to the STRING database.
First level regulatory network of Atf6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.1 | 0.4 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
| 0.0 | 0.1 | GO:0032763 | regulation of mast cell cytokine production(GO:0032763) regulation of memory T cell differentiation(GO:0043380) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.0 | 0.1 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.0 | 0.1 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.0 | 0.1 | GO:0070827 | chromatin maintenance(GO:0070827) |
| 0.0 | 0.0 | GO:0060577 | pulmonary vein morphogenesis(GO:0060577) |
| 0.0 | 0.0 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 0.0 | 0.0 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 0.1 | GO:0010009 | cytoplasmic side of endosome membrane(GO:0010009) |
| 0.0 | 0.1 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.0 | 0.0 | GO:0005962 | mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 0.0 | 0.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 0.1 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.0 | 0.0 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) histone kinase activity (H3-T6 specific)(GO:0035403) |
| 0.0 | 0.0 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |