Project

GSE49485: Hypoxia transcriptome sequencing of rat brain.

Navigation
Downloads

Results for Atf4

Z-value: 0.38

Motif logo

Transcription factors associated with Atf4

Gene Symbol Gene ID Gene Info
ENSRNOG00000017801 activating transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf4rn6_v1_chr7_+_121480723_1214807230.741.5e-01Click!

Activity profile of Atf4 motif

Sorted Z-values of Atf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_78969013 0.15 ENSRNOT00000019772
ENSRNOT00000057585
fibronectin 1
chr6_-_125723944 0.15 ENSRNOT00000007004
fibulin 5
chr19_-_11057254 0.14 ENSRNOT00000025559
homocysteine inducible ER protein with ubiquitin like domain 1
chr5_-_137372993 0.14 ENSRNOT00000092823
transmembrane protein 125
chr19_+_14508616 0.13 ENSRNOT00000019192
heme oxygenase 1
chr5_+_136669674 0.13 ENSRNOT00000048770
solute carrier family 6 member 9
chr6_-_125723732 0.12 ENSRNOT00000084815
fibulin 5
chr7_+_130296897 0.10 ENSRNOT00000044854
adrenomedullin 2
chr15_-_33527031 0.10 ENSRNOT00000019979
homeobox and leucine zipper encoding
chr1_-_101596822 0.10 ENSRNOT00000028490
fibroblast growth factor 21
chr2_-_149347796 0.08 ENSRNOT00000091020
purinergic receptor P2Y14
chr7_-_101140308 0.07 ENSRNOT00000006279
family with sequence similarity 84, member B
chr3_+_111160205 0.07 ENSRNOT00000019392
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
chr10_-_38782419 0.07 ENSRNOT00000073964
ubiquinol-cytochrome c reductase, complex III subunit VII
chr7_+_70580198 0.06 ENSRNOT00000083472
ENSRNOT00000008941
DNA-damage inducible transcript 3
chr10_-_20622600 0.06 ENSRNOT00000020554
fibrillarin-like 1
chr19_+_53629779 0.06 ENSRNOT00000051352
microtubule-associated protein 1 light chain 3 beta
chr1_+_79727597 0.06 ENSRNOT00000034790

chr15_-_6587367 0.06 ENSRNOT00000038449
zinc finger protein 385D
chr4_-_44136815 0.06 ENSRNOT00000086810
transcription factor EC
chr8_+_22856539 0.06 ENSRNOT00000015381
angiopoietin-like 8
chr4_-_157829241 0.06 ENSRNOT00000026184
lymphotoxin beta receptor
chr2_-_227411964 0.05 ENSRNOT00000019931
synaptopodin 2
chr19_+_37668133 0.05 ENSRNOT00000044971
par-6 family cell polarity regulator alpha
chr19_-_43215281 0.05 ENSRNOT00000025052
alanyl-tRNA synthetase
chr1_+_100473643 0.05 ENSRNOT00000026379
Josephin domain containing 2
chr19_-_43215077 0.05 ENSRNOT00000082151
alanyl-tRNA synthetase
chr4_-_115015965 0.04 ENSRNOT00000014603
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr5_+_145079803 0.04 ENSRNOT00000084202
splicing factor proline and glutamine rich
chr9_+_88110731 0.04 ENSRNOT00000088677
rhomboid domain containing 1
chr16_-_71040847 0.04 ENSRNOT00000020606
steroidogenic acute regulatory protein
chr7_-_141185710 0.04 ENSRNOT00000085033
Fas apoptotic inhibitory molecule 2
chr12_-_11240101 0.04 ENSRNOT00000076423
BUD31 homolog
chr18_-_60002529 0.04 ENSRNOT00000081014
ENSRNOT00000024264
ENSRNOT00000059162
asparaginyl-tRNA synthetase
chr5_+_147375350 0.04 ENSRNOT00000010674
tyrosyl-tRNA synthetase
chr4_+_85235172 0.03 ENSRNOT00000014780
glycyl-tRNA synthetase
chr19_+_37668693 0.03 ENSRNOT00000084970
par-6 family cell polarity regulator alpha
chr1_-_216801656 0.03 ENSRNOT00000050721
cysteinyl-tRNA synthetase
chr10_-_75120247 0.03 ENSRNOT00000011402
lactoperoxidase
chr5_+_62071346 0.03 ENSRNOT00000012478
acidic nuclear phosphoprotein 32 family member B
chr1_-_194769524 0.03 ENSRNOT00000025988
nuclear protein 1, transcriptional regulator
chr9_+_74124016 0.03 ENSRNOT00000019023
carbamoyl-phosphate synthase 1
chr1_+_273854248 0.02 ENSRNOT00000044827
ENSRNOT00000017600
ENSRNOT00000086496
adducin 3
chr7_-_139063752 0.02 ENSRNOT00000072309
protein lifeguard 2-like
chr1_-_198045154 0.02 ENSRNOT00000072875
nuclear protein, transcriptional regulator, 1-like 1
chr6_+_109466060 0.02 ENSRNOT00000011339
Jun dimerization protein 2
chr2_-_189333322 0.02 ENSRNOT00000073599
ENSRNOT00000071253
ENSRNOT00000076325
HCLS1 associated protein X-1
chr5_+_128450680 0.02 ENSRNOT00000010700
thioredoxin domain containing 12
chr8_+_118013612 0.02 ENSRNOT00000056166
microtubule-associated protein 4
chr12_-_11240383 0.02 ENSRNOT00000076149
ENSRNOT00000075987
ENSRNOT00000001307
BUD31 homolog
chr16_-_70998575 0.02 ENSRNOT00000019935
potassium calcium-activated channel subfamily U member 1
chr10_+_84119884 0.02 ENSRNOT00000009951
homeo box B9
chr5_-_150704117 0.02 ENSRNOT00000067455
sestrin 2
chr14_+_44889287 0.02 ENSRNOT00000091312
ENSRNOT00000032273
transmembrane protein 156
chr18_-_67224566 0.01 ENSRNOT00000064947
DCC netrin 1 receptor
chr1_-_263269762 0.01 ENSRNOT00000022309
glutamic-oxaloacetic transaminase 1
chr15_-_35113678 0.01 ENSRNOT00000059677
cathepsin G
chr4_-_163261958 0.01 ENSRNOT00000086390
oxidized low density lipoprotein (lectin-like) receptor 1
chr19_+_49695579 0.01 ENSRNOT00000016963
gigaxonin
chr1_+_102849889 0.01 ENSRNOT00000066791
general transcription factor IIH subunit 1
chr7_-_70829815 0.01 ENSRNOT00000011082
serine hydroxymethyltransferase 2
chr4_+_145440114 0.01 ENSRNOT00000013052
cysteine-rich with EGF-like domains 1
chr7_-_70643169 0.01 ENSRNOT00000010106
inhibin beta E subunit
chr1_-_199624783 0.01 ENSRNOT00000026908
cytochrome c oxidase subunit 6A2
chr7_+_141054494 0.01 ENSRNOT00000088176
transmembrane BAX inhibitor motif containing 6
chr18_-_36579403 0.01 ENSRNOT00000025284
leucyl-tRNA synthetase
chr7_-_117773134 0.01 ENSRNOT00000045135
RecQ like helicase 4
chr4_+_33638709 0.00 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr9_-_84383687 0.00 ENSRNOT00000019685
phenylalanyl-tRNA synthetase, beta subunit
chr12_+_11240761 0.00 ENSRNOT00000001310
PDGFA associated protein 1
chr1_+_142050458 0.00 ENSRNOT00000018107
neugrin, neurite outgrowth associated
chr8_-_13680870 0.00 ENSRNOT00000081616
hephaestin-like 1
chr3_+_170399302 0.00 ENSRNOT00000035245
Cas scaffolding protein family member 4
chr11_+_80319177 0.00 ENSRNOT00000036777
receptor (chemosensory) transporter protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0021539 subthalamus development(GO:0021539)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.0 GO:0017143 insecticide metabolic process(GO:0017143)
0.0 0.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.0 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)