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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Ascl2

Z-value: 0.82

Motif logo

Transcription factors associated with Ascl2

Gene Symbol Gene ID Gene Info
ENSRNOG00000020434 achaete-scute family bHLH transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ascl2rn6_v1_chr1_-_216156409_2161564090.721.7e-01Click!

Activity profile of Ascl2 motif

Sorted Z-values of Ascl2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_21345805 0.95 ENSRNOT00000081296
ENSRNOT00000007802
carbonic anhydrase 8
chr5_-_151459037 0.91 ENSRNOT00000064472
ENSRNOT00000087836
synaptotagmin-like 1
chr4_+_86275717 0.83 ENSRNOT00000016414
protein phosphatase 1, regulatory subunit 17
chr16_+_10250404 0.64 ENSRNOT00000087037
ENSRNOT00000081183
growth differentiation factor 10
chr14_+_4362717 0.64 ENSRNOT00000002887
BarH-like homeobox 2
chr16_-_20807070 0.56 ENSRNOT00000072536
cartilage oligomeric matrix protein
chr1_+_90948976 0.44 ENSRNOT00000056877
succinate dehydrogenase assembly factor 1, mitochondrial
chr7_-_3342491 0.43 ENSRNOT00000081756
retinol dehydrogenase 5
chr5_-_156734541 0.41 ENSRNOT00000021036
cytidine deaminase-like
chr8_-_115167486 0.41 ENSRNOT00000033018
G protein-coupled receptor 62
chr7_+_72924799 0.34 ENSRNOT00000008969
lysosomal protein transmembrane 4 beta
chr16_-_59366824 0.31 ENSRNOT00000015062
similar to 6430573F11Rik protein
chr4_-_150244372 0.30 ENSRNOT00000047685
ret proto-oncogene
chr19_-_52282877 0.30 ENSRNOT00000021271
potassium voltage-gated channel modifier subfamily G member 4
chr6_+_98284170 0.29 ENSRNOT00000031979
ras homolog family member J
chr19_-_55183557 0.27 ENSRNOT00000017317
motilin receptor
chr3_+_2480232 0.27 ENSRNOT00000014489
taperin
chr6_+_58467254 0.27 ENSRNOT00000065396
ets variant 1
chr1_+_100199057 0.27 ENSRNOT00000025831
kallikrein 1
chr10_+_109278712 0.26 ENSRNOT00000065565
hypothetical protein LOC690871
chr16_-_6669045 0.26 ENSRNOT00000067639
protein kinase C, delta
chr1_-_277768368 0.24 ENSRNOT00000023113
actin filament associated protein 1-like 2
chr7_-_130120579 0.24 ENSRNOT00000044376
mitogen-activated protein kinase 12
chr11_+_17538063 0.23 ENSRNOT00000031889
ENSRNOT00000090878
chondrolectin
chr9_+_10339075 0.22 ENSRNOT00000073402
vimentin-type intermediate filament associated coiled-coil protein
chr5_-_155772040 0.22 ENSRNOT00000036788
chymotrypsin-like elastase family, member 3B
chr1_-_89560719 0.22 ENSRNOT00000028653
sodium voltage-gated channel beta subunit 1
chr1_+_221470674 0.21 ENSRNOT00000054835
N-acetylated alpha-linked acidic dipeptidase-like 1
chr7_-_107634287 0.21 ENSRNOT00000093672
ENSRNOT00000087116
src-like adaptor
chrX_-_158925630 0.20 ENSRNOT00000073396
cancer/testis antigen family 45 member A9
chr10_+_86399827 0.20 ENSRNOT00000009299
growth factor receptor bound protein 7
chr17_-_43776460 0.20 ENSRNOT00000089055
histone cluster 2, H3c2
chr1_+_222310920 0.20 ENSRNOT00000091465
MACRO domain containing 1
chr12_-_38995570 0.20 ENSRNOT00000001806
ORAI calcium release-activated calcium modulator 1
chr1_-_89560469 0.20 ENSRNOT00000079091
sodium voltage-gated channel beta subunit 1
chr7_-_130350570 0.20 ENSRNOT00000055805
outer dense fiber of sperm tails 3B
chr5_+_139963002 0.19 ENSRNOT00000048506
collagen type IX alpha 2 chain
chr1_+_86938138 0.19 ENSRNOT00000075601
coiled-coil glutamate-rich protein 2
chr12_+_24761210 0.19 ENSRNOT00000002003
claudin 4
chr1_-_265298797 0.18 ENSRNOT00000023137
DNA polymerase lambda
chr10_+_13839956 0.18 ENSRNOT00000012794
BRICHOS domain containing 5
chr11_+_72705129 0.18 ENSRNOT00000073330
apolipoprotein D
chr8_-_61917125 0.18 ENSRNOT00000085049
similar to human chromosome 15 open reading frame 39
chr19_-_37427989 0.18 ENSRNOT00000022863
tubulin polymerization-promoting protein family member 3
chr2_+_187740531 0.17 ENSRNOT00000092653
progestin and adipoQ receptor family member 6
chr1_-_43831932 0.17 ENSRNOT00000082931
Cnksr family member 3
chr15_-_28406046 0.17 ENSRNOT00000015418
zinc finger protein 219
chrX_+_134539398 0.17 ENSRNOT00000004958
CXXC finger protein 5
chr20_+_3677474 0.16 ENSRNOT00000047663
metallothionein 1M
chr15_-_37983882 0.16 ENSRNOT00000087978
large tumor suppressor kinase 2
chr9_+_80118029 0.16 ENSRNOT00000023068
insulin-like growth factor binding protein 2
chr5_-_134526089 0.16 ENSRNOT00000013321
cytochrome P450, family 4, subfamily b, polypeptide 1
chr10_-_57243435 0.16 ENSRNOT00000005050
cholinergic receptor nicotinic epsilon subunit
chr4_-_180505916 0.16 ENSRNOT00000086465

chr20_+_4966817 0.16 ENSRNOT00000081527
ENSRNOT00000081265
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr17_-_13393243 0.16 ENSRNOT00000018252
growth arrest and DNA-damage-inducible, gamma
chr20_+_2004052 0.16 ENSRNOT00000001008
myelin oligodendrocyte glycoprotein
chr1_-_8751198 0.16 ENSRNOT00000030511
adhesion G protein-coupled receptor G6
chr16_+_20555395 0.16 ENSRNOT00000026652
growth differentiation factor 15
chr5_-_142845116 0.15 ENSRNOT00000065105
RGD1559909
chr1_+_226687258 0.15 ENSRNOT00000079679
von Willebrand factor C and EGF domains
chr13_+_71107465 0.15 ENSRNOT00000003239
regulator of G-protein signaling 8
chr1_-_7801438 0.15 ENSRNOT00000022273

chr18_+_24708115 0.15 ENSRNOT00000061054
LIM zinc finger domain containing 2
chr10_-_45534570 0.14 ENSRNOT00000058362
gap junction protein, gamma 2
chr4_-_129430251 0.14 ENSRNOT00000067881
family with sequence similarity 19 member A4, C-C motif chemokine like
chr3_-_168018410 0.14 ENSRNOT00000087579
breast carcinoma amplified sequence 1
chr14_+_16491573 0.14 ENSRNOT00000002995
sosondowah ankyrin repeat domain family member B
chr1_+_203524426 0.14 ENSRNOT00000028020
BUB3 mitotic checkpoint protein
chr1_-_89559960 0.14 ENSRNOT00000092133
sodium voltage-gated channel beta subunit 1
chr3_+_119014620 0.14 ENSRNOT00000067700
solute carrier family 27 member 2
chr1_-_215846911 0.14 ENSRNOT00000089171
insulin-like growth factor 2
chr1_+_222311253 0.14 ENSRNOT00000028749
MACRO domain containing 1
chr4_-_50860756 0.14 ENSRNOT00000068404
calcium dependent secretion activator 2
chr1_+_141550633 0.14 ENSRNOT00000020047
mesoderm posterior bHLH transcription factor 2
chr3_+_175144495 0.13 ENSRNOT00000082601
ENSRNOT00000088026
cadherin 4
chr19_-_43911057 0.13 ENSRNOT00000026017
chymotrypsinogen B1
chr1_+_98440186 0.13 ENSRNOT00000024150
IgLON family member 5
chr15_+_45834302 0.13 ENSRNOT00000051307
serpin family E member 3
chr1_+_40529045 0.13 ENSRNOT00000026564
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr7_-_107616038 0.13 ENSRNOT00000088752
src-like adaptor
chr10_-_38838272 0.12 ENSRNOT00000089495
sosondowah ankyrin repeat domain family member A
chr10_-_39373437 0.12 ENSRNOT00000058907
solute carrier family 22 member 5
chr20_+_13732198 0.12 ENSRNOT00000008608
macrophage migration inhibitory factor
chr16_-_19399851 0.12 ENSRNOT00000089056
ENSRNOT00000021073
tropomyosin 4
chr4_-_89151184 0.12 ENSRNOT00000010263
nucleosome assembly protein 1-like 5
chr10_-_88325222 0.12 ENSRNOT00000021322
ENSRNOT00000076585
prolyl 3-hydroxylase family member 4 (non-enzymatic)
chr14_+_66598259 0.12 ENSRNOT00000049743
potassium voltage-gated channel interacting protein 4
chr13_-_52752997 0.11 ENSRNOT00000013531
plakophilin 1
chr1_-_242765807 0.11 ENSRNOT00000020763
phosphoglucomutase 5
chr17_+_76079720 0.11 ENSRNOT00000073933
proline and serine rich 2
chr6_-_110904288 0.11 ENSRNOT00000014645
interferon regulatory factor 2 binding protein-like
chr15_-_29360198 0.11 ENSRNOT00000072745
T-cell receptor alpha chain V region PHDS58-like
chr20_+_5446104 0.11 ENSRNOT00000000550
Beta-1,3-galactosyltransferase 4
chr3_+_119015412 0.11 ENSRNOT00000013605
solute carrier family 27 member 2
chr10_+_59799123 0.11 ENSRNOT00000026493
transient receptor potential cation channel, subfamily V, member 1
chr8_+_75516904 0.11 ENSRNOT00000013142
RAR-related orphan receptor A
chr5_-_137372524 0.11 ENSRNOT00000009061
transmembrane protein 125
chr15_-_29369504 0.11 ENSRNOT00000060297

chr15_+_31243097 0.11 ENSRNOT00000042721
RGD1359684 protein-like
chr4_-_157358262 0.11 ENSRNOT00000021481
G protein subunit beta 3
chr5_+_151776004 0.11 ENSRNOT00000009683
nuclear receptor subfamily 0, group B, member 2
chrX_-_23187341 0.11 ENSRNOT00000000180
5'-aminolevulinate synthase 2
chr10_+_47490153 0.10 ENSRNOT00000003182
aldehyde dehydrogenase 3 family, member A1
chr5_-_82168347 0.10 ENSRNOT00000084959
ENSRNOT00000084147
astrotactin 2
chr2_+_22000106 0.10 ENSRNOT00000061812
ankyrin repeat domain 34B
chr4_-_157358007 0.10 ENSRNOT00000090898
G protein subunit beta 3
chr4_-_179700130 0.10 ENSRNOT00000021306
lamin tail domain containing 1
chr10_-_71837851 0.10 ENSRNOT00000000258
apoptosis antagonizing transcription factor
chr1_+_282134981 0.10 ENSRNOT00000036203
nanos C2HC-type zinc finger 1
chr4_-_100099517 0.10 ENSRNOT00000014277
atonal bHLH transcription factor 8
chr8_-_122841477 0.10 ENSRNOT00000014861
CKLF-like MARVEL transmembrane domain containing 7
chr11_+_31428358 0.10 ENSRNOT00000002827
oligodendrocyte transcription factor 1
chr12_+_2180150 0.10 ENSRNOT00000001322
syntaxin binding protein 2
chr10_+_76280933 0.10 ENSRNOT00000051823
similar to Tceb2 protein
chr3_+_2648885 0.09 ENSRNOT00000020339
ATP binding cassette subfamily A member 2
chr10_-_105412627 0.09 ENSRNOT00000034817
glutamine rich 2
chr4_+_28972434 0.09 ENSRNOT00000014219
G protein subunit gamma transducin 1
chr3_-_176465162 0.09 ENSRNOT00000048807
Sodium/potassium transporting ATPase interacting 4
chr1_-_227359809 0.09 ENSRNOT00000088080
RIKEN cDNA 1700025F22 gene
chr2_-_202816562 0.09 ENSRNOT00000020401
family with sequence similarity 46, member C
chr13_+_47602692 0.09 ENSRNOT00000038822
Fc fragment of IgM receptor
chr20_+_4967194 0.09 ENSRNOT00000070846
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr4_-_132296413 0.08 ENSRNOT00000052326
similar to macrophage migration inhibitory factor
chr18_+_54206651 0.08 ENSRNOT00000073295
chondroitin sulfate synthase 3
chr10_-_14072230 0.08 ENSRNOT00000018405
transducin (beta)-like 3
chr8_-_47494982 0.08 ENSRNOT00000012170
POU class 2 homeobox 3
chr8_+_5993941 0.08 ENSRNOT00000014065
transmembrane protein 123
chr9_-_10757720 0.08 ENSRNOT00000083848
ubiquitin-like with PHD and ring finger domains 1
chr7_-_3315856 0.08 ENSRNOT00000010035
growth differentiation factor 11
chr2_-_192381716 0.08 ENSRNOT00000064950

chr6_+_51662224 0.08 ENSRNOT00000060006
coiled-coil domain containing 71-like
chr10_-_70220558 0.08 ENSRNOT00000041389
ENSRNOT00000076398
ENSRNOT00000076596
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chrX_-_111102464 0.08 ENSRNOT00000084176
ripply transcriptional repressor 1
chr10_+_103972888 0.08 ENSRNOT00000067838
potassium channel tetramerization domain containing 2
chr8_+_116754178 0.08 ENSRNOT00000068295
ENSRNOT00000084429
ubiquitin-like modifier activating enzyme 7
chr10_+_104359342 0.08 ENSRNOT00000006327
tRNA splicing endonuclease subunit 54
chr12_+_47193964 0.08 ENSRNOT00000001552
ENSRNOT00000039281
calcium binding protein 1
chr16_+_20110148 0.08 ENSRNOT00000080146
ENSRNOT00000025312
Janus kinase 3
chr4_+_144382945 0.08 ENSRNOT00000007601
caveolin 3
chr12_-_21832813 0.08 ENSRNOT00000075280
claudin 3
chr1_-_89369960 0.08 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr9_-_10757954 0.08 ENSRNOT00000075265
ubiquitin-like with PHD and ring finger domains 1
chr8_-_28208466 0.08 ENSRNOT00000012247
junctional adhesion molecule 3
chr20_+_14050465 0.08 ENSRNOT00000089319
ENSRNOT00000074783
leucine rich repeat containing 75B
chr4_+_44573264 0.08 ENSRNOT00000080271
caveolin 2
chr4_+_169161585 0.07 ENSRNOT00000079785
epithelial membrane protein 1
chr14_-_77810147 0.07 ENSRNOT00000035427
cytokine like 1
chr6_+_3657325 0.07 ENSRNOT00000010927
transmembrane protein 178A
chr1_-_213987053 0.07 ENSRNOT00000072774
p53-induced protein with a death domain-like
chrX_+_6791136 0.07 ENSRNOT00000003984
norrin-like
chr2_+_95008311 0.07 ENSRNOT00000077270
tumor protein D52
chrX_-_123601100 0.07 ENSRNOT00000092546
ENSRNOT00000092301
septin 6
chr1_+_83965798 0.07 ENSRNOT00000068322
cytochrome P450, family 2, subfamily t, polypeptide 1
chr20_-_4380084 0.07 ENSRNOT00000000499
EGF-like-domain, multiple 8
chr19_-_11057254 0.07 ENSRNOT00000025559
homocysteine inducible ER protein with ubiquitin like domain 1
chr14_-_86395120 0.07 ENSRNOT00000006802
ENSRNOT00000078572
transmembrane p24 trafficking protein 4
chr4_+_169147243 0.07 ENSRNOT00000011580
epithelial membrane protein 1
chr9_-_95290931 0.07 ENSRNOT00000025300
DnaJ heat shock protein family (Hsp40) member B3
chr4_+_157126935 0.07 ENSRNOT00000056051
complement C1r
chrX_+_123404518 0.07 ENSRNOT00000015085
solute carrier family 25 member 5
chr13_+_48367307 0.06 ENSRNOT00000074512
vasopressin V1b receptor-like
chrX_-_63807810 0.06 ENSRNOT00000084632
MAGE family member D1
chr2_+_45104305 0.06 ENSRNOT00000014559
endothelial cell-specific molecule 1
chr8_+_116324040 0.06 ENSRNOT00000081353
hyaluronoglucosaminidase 2
chr17_-_72046381 0.06 ENSRNOT00000073919

chr18_+_57011575 0.06 ENSRNOT00000026679
interleukin 17B
chr10_+_14216155 0.06 ENSRNOT00000020192
hydroxyacyl glutathione hydrolase
chr19_-_26181449 0.06 ENSRNOT00000036953
similar to Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-12 subunit precursor
chr12_+_24473981 0.06 ENSRNOT00000001973
frizzled class receptor 9
chr4_+_14001761 0.06 ENSRNOT00000076519
CD36 molecule
chr7_+_59349745 0.06 ENSRNOT00000085334
protein tyrosine phosphatase, receptor type, B
chr1_-_226935689 0.06 ENSRNOT00000038807
transmembrane protein 109
chr15_+_50891127 0.06 ENSRNOT00000020728
stanniocalcin 1
chr10_+_5352933 0.06 ENSRNOT00000003465
tektin 5
chr1_+_218076116 0.06 ENSRNOT00000028374
oral cancer overexpressed 1
chr6_-_80334522 0.06 ENSRNOT00000059316
F-box protein 33
chr14_+_13192347 0.06 ENSRNOT00000000092
anthrax toxin receptor 2
chr10_-_15204143 0.06 ENSRNOT00000026971
rhomboid like 1
chr12_-_42492526 0.06 ENSRNOT00000084018
T-box 3
chr1_+_100832324 0.06 ENSRNOT00000056364
interleukin 4 induced 1
chr12_+_9728486 0.06 ENSRNOT00000001263
ligand of numb-protein X 2
chr5_-_164959851 0.06 ENSRNOT00000012301
F-box protein 6
chr2_+_95045034 0.06 ENSRNOT00000081305
mitochondrial ribosomal protein S28
chr19_+_37476095 0.06 ENSRNOT00000092794
ENSRNOT00000023130
hydroxysteroid 11-beta dehydrogenase 2
chr18_+_52215682 0.06 ENSRNOT00000037901
multiple EGF-like domains 10
chr16_+_53998560 0.05 ENSRNOT00000077188
ENSRNOT00000013463
N-acylsphingosine amidohydrolase 1
chr18_+_32594958 0.05 ENSRNOT00000018511
sprouty RTK signaling antagonist 4
chr2_-_30246010 0.05 ENSRNOT00000023900
methylcrotonoyl-CoA carboxylase 2
chr12_-_42492328 0.05 ENSRNOT00000011552
T-box 3
chr1_+_18491384 0.05 ENSRNOT00000079138
ENSRNOT00000014917
laminin subunit alpha 2
chr8_+_94243372 0.05 ENSRNOT00000012864
RWD domain containing 2A
chr9_+_69790831 0.05 ENSRNOT00000045156
ribosomal protein L37-like
chr3_-_147865393 0.05 ENSRNOT00000009852
SRY box 12
chr4_+_129574264 0.05 ENSRNOT00000010185
ADP-ribosylation factor like GTPase 6 interacting protein 5
chr3_+_113415774 0.05 ENSRNOT00000056151
small EDRK-rich factor 2
chr5_-_59025631 0.05 ENSRNOT00000049000
ENSRNOT00000022801
tropomyosin 2, beta
chr7_-_2941122 0.05 ENSRNOT00000082107
extended synaptotagmin 1
chr10_-_45279299 0.05 ENSRNOT00000073082
ring finger protein 187
chr7_-_107768072 0.05 ENSRNOT00000093189
N-myc downstream regulated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Ascl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.4 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.4 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.3 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.2 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.2 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:0015942 formate metabolic process(GO:0015942)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968) regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.0 GO:0072098 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 0.1 GO:0098749 cerebellar neuron development(GO:0098749)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879) antibiotic transport(GO:0042891)
0.0 0.6 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:1901423 response to benzene(GO:1901423)
0.0 1.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.0 GO:0046099 guanine salvage(GO:0006178) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099)
0.0 0.6 GO:0001709 cell fate determination(GO:0001709)
0.0 0.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734) ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.0 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.0 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.0 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0032173 septin collar(GO:0032173)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.0 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0070820 cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.0 GO:2001070 starch binding(GO:2001070)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0016822 oxaloacetate decarboxylase activity(GO:0008948) hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly