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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

Z-value: 0.48

Motif logo

Transcription factors associated with Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

Gene Symbol Gene ID Gene Info
ENSRNOG00000014448 aryl hydrocarbon receptor nuclear translocator-like
ENSRNOG00000009605 transcription factor binding to IGHM enhancer 3
ENSRNOG00000019983 MLX, MAX dimerization protein
ENSRNOG00000008658 melanogenesis associated transcription factor
ENSRNOG00000046171 Mlxipl
ENSRNOG00000061595 transcription factor EC

Activity-expression correlation:

Activity profile of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec motif

Sorted Z-values of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_56610051 0.41 ENSRNOT00000024348
dishevelled segment polarity protein 2
chr1_-_219450451 0.41 ENSRNOT00000025317
RAD9 checkpoint clamp component A
chr11_+_61531416 0.40 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr3_-_161299024 0.34 ENSRNOT00000021216
neuralized E3 ubiquitin protein ligase 2
chr9_+_94425252 0.25 ENSRNOT00000064965
ENSRNOT00000076099
GRB10 interacting GYF protein 2
chr10_+_94988362 0.24 ENSRNOT00000066525
centrosomal protein 95
chr1_-_222495382 0.24 ENSRNOT00000028759
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr3_+_155297566 0.21 ENSRNOT00000021435
ENSRNOT00000084866
DEAH-box helicase 35
chr13_+_41802697 0.20 ENSRNOT00000046719
LRRGT00155-like
chr1_-_92119951 0.20 ENSRNOT00000018153
ENSRNOT00000092121
zinc finger protein 507
chr3_-_61494778 0.20 ENSRNOT00000068018
lunapark, ER junction formation factor
chr7_+_53878610 0.19 ENSRNOT00000091910
oxysterol binding protein-like 8
chr12_+_24367199 0.19 ENSRNOT00000001971
FK506 binding protein 6
chr1_+_154377447 0.19 ENSRNOT00000084268
ENSRNOT00000092086
ENSRNOT00000091470
ENSRNOT00000025415
phosphatidylinositol binding clathrin assembly protein
chr19_+_26151900 0.19 ENSRNOT00000005571
transportin 2
chr7_+_99677290 0.19 ENSRNOT00000086039
ENSRNOT00000005376
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr2_-_33841499 0.18 ENSRNOT00000040533
splicing regulatory glutamic acid and lysine rich protein 1
chr5_-_160352927 0.18 ENSRNOT00000017247
DnaJ heat shock protein family (Hsp40) member C16
chr16_-_2227258 0.17 ENSRNOT00000089377
ENSRNOT00000067464
sarcolemma associated protein
chr10_-_6870011 0.17 ENSRNOT00000003439
similar to CG4768-PA
chr7_-_120874308 0.17 ENSRNOT00000078320
family with sequence similarity 227, member A
chr1_+_144601410 0.17 ENSRNOT00000047408
elongation factor like GTPase 1
chr6_+_108167716 0.17 ENSRNOT00000064426
lin-52 DREAM MuvB core complex component
chr5_+_141572536 0.17 ENSRNOT00000023514
Ras-related GTP binding C
chr14_-_17616170 0.16 ENSRNOT00000090938
THAP domain containing 6
chr10_+_56546710 0.16 ENSRNOT00000023003
Y box binding protein 2
chr13_-_70174565 0.15 ENSRNOT00000067135
ral guanine nucleotide dissociation stimulator,-like 1
chr10_-_46720907 0.15 ENSRNOT00000083093
ENSRNOT00000067866
target of myb1 like 2 membrane trafficking protein
chr8_-_36467627 0.15 ENSRNOT00000082346
family with sequence similarity 118, member B
chr18_+_74299931 0.15 ENSRNOT00000078403
ectopic P-granules autophagy protein 5 homolog
chr11_-_68197772 0.14 ENSRNOT00000003060
ENSRNOT00000081875
Hspb associated protein 1
chr4_+_33638709 0.14 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr6_+_86785771 0.14 ENSRNOT00000066702
pre-mRNA processing factor 39
chr6_-_55001464 0.14 ENSRNOT00000006618
aryl hydrocarbon receptor
chr14_-_3462629 0.14 ENSRNOT00000061538
bromodomain testis associated
chr10_+_71278650 0.14 ENSRNOT00000092020
synergin, gamma
chr7_-_70498992 0.14 ENSRNOT00000067774
ENSRNOT00000079327
phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
chr14_-_44767120 0.14 ENSRNOT00000003991
WD repeat domain 19
chr9_-_15700235 0.14 ENSRNOT00000088713
ENSRNOT00000035907
transcriptional regulating factor 1
chr10_+_11373346 0.13 ENSRNOT00000044624
coronin-7-like
chr13_+_89597138 0.13 ENSRNOT00000004662
apolipoprotein A2
chr19_-_10826895 0.13 ENSRNOT00000090217
ring finger and SPRY domain containing 1
chr2_-_189400323 0.13 ENSRNOT00000024364
ubiquitin associated protein 2-like
chr13_-_111948753 0.13 ENSRNOT00000048074
hydroxysteroid 11-beta dehydrogenase 1
chr9_-_16979044 0.13 ENSRNOT00000073191
ENSRNOT00000025335
zinc finger protein 318
chr7_+_41114697 0.13 ENSRNOT00000041354
ATPase plasma membrane Ca2+ transporting 1
chr6_-_102472926 0.13 ENSRNOT00000079351
zinc finger FYVE-type containing 26
chr7_+_64769089 0.13 ENSRNOT00000088861
glutamate receptor interacting protein 1
chr5_+_74649765 0.13 ENSRNOT00000075952
paralemmin 2
chr7_-_99677268 0.12 ENSRNOT00000013315
similar to Hypothetical protein MGC31278
chr8_-_94922017 0.12 ENSRNOT00000083934
centrosomal protein 162
chr8_-_58253688 0.12 ENSRNOT00000010956
cullin 5
chr8_+_96551245 0.12 ENSRNOT00000039850
BCL2-related protein A1
chr10_-_13996565 0.12 ENSRNOT00000016221
ENSRNOT00000052138
tuberous sclerosis 2
chr10_-_89916400 0.11 ENSRNOT00000055194
dual specificity phosphatase 3
chr17_-_66397653 0.11 ENSRNOT00000024098
actinin alpha 2
chr6_-_125853461 0.11 ENSRNOT00000007505
ataxin 3
chr11_+_73936750 0.11 ENSRNOT00000002350
ATPase 13A3
chr10_-_10725655 0.11 ENSRNOT00000061236
ubinuclein 1
chr2_-_178521038 0.11 ENSRNOT00000033107
relaxin/insulin-like family peptide receptor 1
chr2_+_184600721 0.11 ENSRNOT00000075823
glutamyl-tRNA amidotransferase subunit B
chr1_-_102849430 0.11 ENSRNOT00000086856
serum amyloid A4
chr17_+_10463303 0.11 ENSRNOT00000060822
ring finger protein 44
chr5_-_86696388 0.11 ENSRNOT00000007812
multiple EGF-like-domains 9
chr15_-_60766579 0.11 ENSRNOT00000079978
A-kinase anchoring protein 11
chr17_-_67904674 0.11 ENSRNOT00000078532
Kruppel-like factor 6
chr4_+_163358009 0.10 ENSRNOT00000082064
killer cell lectin like receptor D1
chr8_-_132790778 0.10 ENSRNOT00000008255
ENSRNOT00000091431
leucine zipper transcription factor-like 1
chr7_+_108613739 0.10 ENSRNOT00000007564
PHD finger protein 20-like 1
chr8_-_123371257 0.10 ENSRNOT00000017243
STT3B, catalytic subunit of the oligosaccharyltransferase complex
chr5_-_164844586 0.10 ENSRNOT00000011287
chloride voltage-gated channel 6
chr3_+_58084606 0.10 ENSRNOT00000084797
methionyl aminopeptidase type 1D (mitochondrial)
chr2_-_142686577 0.10 ENSRNOT00000014562
NHL repeat containing 3
chr8_+_408001 0.10 ENSRNOT00000046058
guanylate cyclase 1 soluble subunit alpha 2
chrX_-_54303729 0.10 ENSRNOT00000087919
ENSRNOT00000064340
ENSRNOT00000051249
ENSRNOT00000087547
glycerol kinase
chr8_-_49280901 0.09 ENSRNOT00000021390
CD3g molecule
chr2_-_178616719 0.09 ENSRNOT00000078610
transmembrane protein 144
chr12_+_37594185 0.09 ENSRNOT00000088787
strawberry notch homolog 1
chr14_+_63095720 0.09 ENSRNOT00000006071
PPARG coactivator 1 alpha
chr7_-_12673659 0.09 ENSRNOT00000091650
ENSRNOT00000041277
ENSRNOT00000044865
polypyrimidine tract binding protein 1
chr2_-_219262901 0.09 ENSRNOT00000037068
G-protein coupled receptor 88
chr5_+_145138697 0.09 ENSRNOT00000019135
zinc finger MYM-type containing 6
chr7_+_23960378 0.09 ENSRNOT00000006886
PR/SET domain 4
chr10_-_74298599 0.09 ENSRNOT00000007379
yippee-like 2
chr4_-_168297373 0.09 ENSRNOT00000066575
LDL receptor related protein 6
chr3_+_8928534 0.09 ENSRNOT00000088509
ENSRNOT00000065300
mitoguardin 2
chr6_-_50846965 0.09 ENSRNOT00000087300
solute carrier family 26 member 4
chr6_+_111642411 0.09 ENSRNOT00000016962
aarF domain containing kinase 1
chr10_-_39054142 0.09 ENSRNOT00000063772
RAD50 double strand break repair protein
chr11_+_34598492 0.09 ENSRNOT00000065600
tetratricopeptide repeat domain 3
chr5_+_147535525 0.09 ENSRNOT00000074628
zinc finger and BTB domain containing 8 opposite strand
chr9_-_11027506 0.09 ENSRNOT00000071107
chromatin assembly factor 1 subunit A
chr10_+_47019326 0.09 ENSRNOT00000006984
Smith-Magenis syndrome chromosome region, candidate 8
chr7_-_95669809 0.09 ENSRNOT00000006423
syntrophin, beta 1
chr19_-_55510460 0.08 ENSRNOT00000019820
CBFA2/RUNX1 translocation partner 3
chr1_+_48176106 0.08 ENSRNOT00000021840
insulin-like growth factor 2 receptor
chr9_+_73378057 0.08 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr1_+_199287710 0.08 ENSRNOT00000082121
syntaxin 4
chr18_-_56115593 0.08 ENSRNOT00000045041
treacle ribosome biogenesis factor 1
chr2_-_60683451 0.08 ENSRNOT00000046215
retinoic acid induced 14
chr2_-_196270826 0.08 ENSRNOT00000028609
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
chr13_-_42263024 0.08 ENSRNOT00000004741
Ly6/Plaur domain containing 1
chr10_-_47018537 0.08 ENSRNOT00000068351
ENSRNOT00000080083
topoisomerase (DNA) III alpha
chr13_+_80464348 0.08 ENSRNOT00000076324
vesicle-associated membrane protein 4
chr10_-_36419926 0.08 ENSRNOT00000004902
zinc finger protein 354B
chr16_-_49820235 0.08 ENSRNOT00000029628
sorbin and SH3 domain containing 2
chr5_+_35991068 0.08 ENSRNOT00000061139
PNN interacting serine and arginine rich protein
chr18_+_24397369 0.08 ENSRNOT00000022761
Sin3A associated protein 130
chr1_-_239265997 0.08 ENSRNOT00000037500
similar to RIKEN cDNA 1110059E24
chr13_+_99136871 0.08 ENSRNOT00000078263
ENSRNOT00000004350
SDE2 telomere maintenance homolog
chr6_+_109617355 0.08 ENSRNOT00000011599
feline leukemia virus subgroup C cellular receptor family, member 2
chrX_+_106774980 0.08 ENSRNOT00000046091
transcription elongation factor A like 7
chr8_-_115981910 0.08 ENSRNOT00000019867
dedicator of cyto-kinesis 3
chr14_-_80130139 0.08 ENSRNOT00000091652
ENSRNOT00000010482
actin binding LIM protein family, member 2
chr2_+_118746333 0.08 ENSRNOT00000079431

chr8_+_22446661 0.08 ENSRNOT00000010030
queuine tRNA-ribosyltransferase catalytic subunit 1
chr3_-_111037425 0.08 ENSRNOT00000085628
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr16_-_54137660 0.07 ENSRNOT00000085435
pericentriolar material 1
chr10_-_37455022 0.07 ENSRNOT00000016742
ubiquitin-conjugating enzyme E2 B
chr13_+_101698096 0.07 ENSRNOT00000089309
axin interactor, dorsalization associated
chr19_+_26416818 0.07 ENSRNOT00000040473

chr15_+_33271015 0.07 ENSRNOT00000073767
proteasome subunit beta 11
chr7_-_120882392 0.07 ENSRNOT00000056179
ENSRNOT00000056178
family with sequence similarity 227, member A
chr1_+_65576535 0.07 ENSRNOT00000026575
solute carrier family 27 member 5
chrX_-_105622156 0.07 ENSRNOT00000029511
armadillo repeat containing, X-linked 2
chrX_-_106607352 0.07 ENSRNOT00000082858

chr18_+_14756684 0.07 ENSRNOT00000076085
ENSRNOT00000076129
microtubule-associated protein, RP/EB family, member 2
chr16_-_24788456 0.07 ENSRNOT00000079412
neuropeptide Y receptor Y1
chrX_-_38196060 0.07 ENSRNOT00000006741
ENSRNOT00000006438
SH3 domain-containing kinase-binding protein 1
chr15_-_45927804 0.07 ENSRNOT00000086271
integrator complex subunit 6
chr19_-_6031655 0.07 ENSRNOT00000092016

chr17_+_1936163 0.07 ENSRNOT00000024466
cyclin-dependent kinase 20
chr9_+_71398710 0.07 ENSRNOT00000049411
cyclin Y-like 1
chr10_+_31647898 0.07 ENSRNOT00000066536
similar to kidney injury molecule 1
chr12_-_19599374 0.07 ENSRNOT00000001849
glypican 2
chr12_-_13462038 0.07 ENSRNOT00000043110
ribosomal protein L36-like
chr10_+_10573191 0.07 ENSRNOT00000003888
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr16_-_21473808 0.07 ENSRNOT00000066776
zinc finger protein 964
chr10_-_16752205 0.07 ENSRNOT00000079462
CREB3 regulatory factor
chr1_-_131585731 0.07 ENSRNOT00000075481

chr10_+_14492844 0.07 ENSRNOT00000023615
chloride voltage-gated channel 7
chr10_-_62287189 0.07 ENSRNOT00000004365
WD repeat domain 81
chr5_+_138470069 0.07 ENSRNOT00000076343
ENSRNOT00000064073
zinc finger, MYND-type containing 12
chr20_-_32416044 0.07 ENSRNOT00000067004
cell division cycle and apoptosis regulator 1
chr20_-_4316715 0.07 ENSRNOT00000031704
complement C4B (Chido blood group)
chr6_-_127248372 0.07 ENSRNOT00000085517
ankyrin repeat and SOCS box-containing 2
chr11_-_83483513 0.07 ENSRNOT00000084380

chr3_-_102151489 0.07 ENSRNOT00000006349
anoctamin 3
chr3_-_60795951 0.07 ENSRNOT00000002174
activating transcription factor 2
chr5_+_128215711 0.07 ENSRNOT00000011670
coiled-coil and C2 domain containing 1B
chr19_-_37210412 0.07 ENSRNOT00000083097
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr10_-_2037891 0.07 ENSRNOT00000004563
ERCC excision repair 4, endonuclease catalytic subunit
chr5_+_154800226 0.07 ENSRNOT00000016046
5-hydroxytryptamine receptor 1D
chr9_+_73319710 0.07 ENSRNOT00000092485
microtubule-associated protein 2
chr18_+_55797198 0.07 ENSRNOT00000026334
ENSRNOT00000026394
dynactin subunit 4
chr16_-_24788740 0.07 ENSRNOT00000018952
neuropeptide Y receptor Y1
chr5_-_173425611 0.06 ENSRNOT00000027060
Beta-1,3-galactosyltransferase 6
chr16_+_8497569 0.06 ENSRNOT00000027054
oxoglutarate dehydrogenase-like
chr17_+_86408151 0.06 ENSRNOT00000022734
OTU deubiquitinase 1
chr1_+_104635989 0.06 ENSRNOT00000078477
neuron navigator 2
chr2_-_53827175 0.06 ENSRNOT00000078158
similar to expressed sequence AW549877
chr8_-_53362006 0.06 ENSRNOT00000077145
claudin 25-like
chrX_+_19854836 0.06 ENSRNOT00000075010

chr17_-_32661865 0.06 ENSRNOT00000022194
serpin family B member 9
chr18_-_76753902 0.06 ENSRNOT00000078797
heat shock factor binding protein 1-like 1
chr9_-_104350308 0.06 ENSRNOT00000033958
solute carrier organic anion transporter family, member 4C1
chr7_-_15821927 0.06 ENSRNOT00000050658
similar to zinc finger protein 101
chr3_+_163570532 0.06 ENSRNOT00000010054
ADP ribosylation factor guanine nucleotide exchange factor 2
chr20_-_27208041 0.06 ENSRNOT00000084720
RUN and FYVE domain containing 2
chr10_+_57462447 0.06 ENSRNOT00000041443
rabaptin, RAB GTPase binding effector protein 1
chr16_-_85306366 0.06 ENSRNOT00000089650
tumor necrosis factor superfamily member 13b
chr1_+_100299626 0.06 ENSRNOT00000092327
ENSRNOT00000044257
SH3 and multiple ankyrin repeat domains 1
chr1_+_192233910 0.06 ENSRNOT00000016418
ENSRNOT00000016442
protein kinase C, beta
chr1_-_78686952 0.06 ENSRNOT00000047079
similar to Macrophage migration inhibitory factor (MIF) (Phenylpyruvate tautomerase) (Glycosylation-inhibiting factor) (GIF) (Delayed early response protein 6) (DER6)
chr1_-_216971183 0.06 ENSRNOT00000077911
MAS related GPR family member E
chr10_+_10725819 0.06 ENSRNOT00000004159
glyoxylate reductase 1 homolog
chr2_-_179704629 0.06 ENSRNOT00000083361
ENSRNOT00000077941
glutamate ionotropic receptor AMPA type subunit 2
chr6_-_3794489 0.06 ENSRNOT00000087891
ENSRNOT00000011000
ENSRNOT00000084499
THUMP domain containing 2
chr1_+_274310153 0.06 ENSRNOT00000054686
structural maintenance of chromosomes 3
chr17_-_32783427 0.06 ENSRNOT00000059921
serine (or cysteine) peptidase inhibitor, clade B, member 6b
chr3_-_123179644 0.06 ENSRNOT00000028835
leucine zipper tumor suppressor family member 3
chr2_+_104416972 0.06 ENSRNOT00000017125
tripartite motif-containing 55
chr13_-_101697684 0.06 ENSRNOT00000078834
BRO1 domain and CAAX motif containing
chr4_-_81968832 0.06 ENSRNOT00000016608
src kinase associated phosphoprotein 2
chr1_-_151106802 0.06 ENSRNOT00000021971
tyrosinase
chr6_-_108976489 0.06 ENSRNOT00000007350
ribosomal protein S6 kinase-like 1
chr5_-_60955943 0.06 ENSRNOT00000071116
mitochondrial carrier triple repeat 1
chr1_+_213583606 0.06 ENSRNOT00000088899

chr1_+_212181374 0.06 ENSRNOT00000085921
adhesion G protein-coupled receptor A1
chr3_+_2182957 0.06 ENSRNOT00000011633
patatin-like phospholipase domain containing 7
chr11_+_61531571 0.06 ENSRNOT00000093467
ENSRNOT00000002727
ATPase H+ transporting V1 subunit A
chr10_-_31359699 0.06 ENSRNOT00000081280
cytoplasmic FMR1 interacting protein 2
chr1_+_79790705 0.06 ENSRNOT00000018233
peptidoglycan recognition protein 1
chr1_+_87045796 0.06 ENSRNOT00000027620
galectin 7
chr1_-_16203838 0.06 ENSRNOT00000018556
ENSRNOT00000078586
phosphodiesterase 7B
chr2_-_167607919 0.06 ENSRNOT00000089083

chr10_+_109852036 0.06 ENSRNOT00000054944
ASPSCR1, UBX domain containing tether for SLC2A4
chr7_-_9976367 0.06 ENSRNOT00000044241
zinc finger protein 347
chr4_+_116968000 0.05 ENSRNOT00000020786
empty spiracles homeobox 1
chr1_-_198117547 0.05 ENSRNOT00000077226
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.1 0.2 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.2 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.0 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.2 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.1 GO:0051695 actin filament uncapping(GO:0051695) positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0071250 cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033) regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.1 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0048550 protein transport into plasma membrane raft(GO:0044861) negative regulation of pinocytosis(GO:0048550)
0.0 0.0 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0019563 glycerol catabolic process(GO:0019563)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:1905233 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.0 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.0 GO:0015755 fructose transport(GO:0015755)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:1900224 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.0 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.0 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.0 GO:0042245 RNA repair(GO:0042245)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.0 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.0 GO:1904170 NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:0009758 carbohydrate utilization(GO:0009758)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0030432 peristalsis(GO:0030432)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0033668 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 0.2 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.0 GO:0035973 aggrephagy(GO:0035973)
0.0 0.0 GO:1904976 cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.0 GO:0090361 positive regulation of fibroblast growth factor production(GO:0090271) platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.0 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.0 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.0 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.0 GO:1900145 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.0 0.0 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.0 GO:0035106 operant conditioning(GO:0035106)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0045203 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.0 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.0 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.0 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.0 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.0 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.0 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.0 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint