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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Aire
Z-value: 0.47
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Transcription factors associated with Aire
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Aire | rn6_v1_chr20_+_11365697_11365697 | -0.29 | 6.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_23135354 Show fit | 0.14 |
ENSRNOT00000011432
|
STEAP4 metalloreductase |
|
| chr2_+_209661244 Show fit | 0.12 |
ENSRNOT00000091973
|
|
|
| chrM_+_9451 Show fit | 0.12 |
ENSRNOT00000041241
|
mitochondrially encoded NADH dehydrogenase 3 |
|
| chrM_+_14136 Show fit | 0.11 |
ENSRNOT00000042098
|
mitochondrially encoded cytochrome b |
|
| chr8_+_52751854 Show fit | 0.09 |
ENSRNOT00000072518
|
neurexophilin and PC-esterase domain family, member 1 |
|
| chr15_-_83494423 Show fit | 0.09 |
ENSRNOT00000037588
|
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease |
|
| chrM_+_7006 Show fit | 0.09 |
ENSRNOT00000043693
|
mitochondrially encoded cytochrome c oxidase II |
|
| chr18_-_36513317 Show fit | 0.08 |
ENSRNOT00000025453
|
PLAC8-like 1 |
|
| chr20_+_34633157 Show fit | 0.08 |
ENSRNOT00000000469
|
phospholamban |
|
| chr1_-_66212418 Show fit | 0.08 |
ENSRNOT00000026074
|
hypothetical protein LOC691722 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Aire
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0071283 | response to high light intensity(GO:0009644) cellular response to iron(III) ion(GO:0071283) |
| 0.0 | 0.1 | GO:0009609 | response to symbiotic bacterium(GO:0009609) |
| 0.0 | 0.1 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 0.0 | 0.1 | GO:0098706 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.0 | 0.1 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.0 | 0.1 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
| 0.0 | 0.0 | GO:0052422 | modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) |
| 0.0 | 0.0 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 0.0 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.0 | 0.0 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0090534 | calcium ion-transporting ATPase complex(GO:0090534) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.0 | 0.1 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.0 | 0.0 | GO:0032142 | dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142) |
| 0.0 | 0.0 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.0 | GO:0003865 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751) |