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GSE80451: E.coli grown aerobically and anaerobically

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Results for Rob

Z-value: 0.41

Transcription factors associated with Rob

Gene Symbol Gene ID Gene Info
rob
rob Rob DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rob-0.523.7e-01Click!

Activity profile of Rob motif

Sorted Z-values of Rob motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
nfo 1.09
nfo
endonuclease IV
tolC-ygiABC 0.93
ygiC
ygiB
ygiA
tolC
predicted enzyme with ATPase activity
conserved outer membrane protein
predicted protein
TolC outer membrane channel
marRAB 0.73
marB
marA
marR
multiple antibiotic resistance protein
MarA DNA-binding transcriptional dual regulator
MarR DNA-binding transcriptional repressor
ybjC-nfsA-rimK-ybjN 0.67
nfsA
ybjN
ybjC
rimK
NADPH nitroreductase NfsA
predicted oxidoreductase
predicted inner membrane protein
ribosomal protein S6 modification protein
mltF 0.65
mltF
membrane-bound lytic murein transglycosylase F
rob 0.47
rob
Rob DNA-binding transcriptional dual regulator
acrAB 0.29
acrB
acrA
AcrAB-TolC multidrug efflux pump - permease subunit
AcrAB-TolC multidrug efflux pump - membrane fusion protein
nfsB 0.11
nfsB
NAD(P)H nitroreductase NfsB
zwf 0.09
zwf
glucose-6-phosphate dehydrogenase (NADP+)
inaA 0.08
inaA
pH-inducible protein involved in stress response

Network of associatons between targets according to the STRING database.

First level regulatory network of Rob

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0006284 base-excision repair(GO:0006284)
0.2 0.7 GO:1900232 negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) post-translational protein modification(GO:0043687) response to alcohol(GO:0097305) regulation of single-species biofilm formation on inanimate substrate(GO:1900231) negative regulation of single-species biofilm formation on inanimate substrate(GO:1900232) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209)
0.2 0.6 GO:0006026 aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027) peptidoglycan catabolic process(GO:0009253)
0.2 0.9 GO:0015891 siderophore transport(GO:0015891)
0.1 0.7 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0072490 trinitrotoluene metabolic process(GO:0018973) 2,4,6-trinitrotoluene metabolic process(GO:0018974) nitrotoluene metabolic process(GO:0019326) 2,4,6-trinitrotoluene catabolic process(GO:0046256) trinitrotoluene catabolic process(GO:0046260) nitrotoluene catabolic process(GO:0046263) toluene-containing compound metabolic process(GO:0072490) toluene-containing compound catabolic process(GO:0072491)
0.0 0.3 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0048872 homeostasis of number of cells(GO:0048872) homeostasis of number of cells in a free-living population(GO:0048874)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 GO:1902495 transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351)
0.0 0.7 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034567 chromate reductase activity(GO:0034567)
0.2 0.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 1.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.7 GO:0044212 regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.0 0.6 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 0.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.5 GO:0043565 sequence-specific DNA binding(GO:0043565)