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GSE80451: E.coli grown aerobically and anaerobically

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Results for PhoP

Z-value: 0.43

Transcription factors associated with PhoP

Gene Symbol Gene ID Gene Info
phoP PhoP

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
phoP0.019.9e-01Click!

Activity profile of PhoP motif

Sorted Z-values of PhoP motif

Promoter Log-likelihood Transcript Gene Gene Info
rstAB 0.70 RstA transcriptional regulator
RstB sensory histidine kinase
treR 0.47 TreR DNA-binding transcriptional repressor
mgrR 0.42 MgrR
mgtLA 0.40 Mg2+ / Ni2+ transporting ATPase
predicted leader peptide
ompT 0.24 outer membrane protease VII (outer membrane protein 3b)
metBL 0.23 O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase
aspartate kinase / homoserine dehydrogenase
argD 0.21 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase
mgrB 0.12 negative feedback regulator of the PhoQP system
gadE 0.10 GadE DNA-binding transcriptional activator
cysB 0.10 CysB transcriptional dual regulator
acrAB 0.07 AcrAB-TolC multidrug efflux pump - permease subunit
AcrAB-TolC multidrug efflux pump - membrane fusion protein
hdeAB-yhiD 0.07 inner membrane protein YhiD
HdeB monomer
HdeA monomer, chaperone active form
dcuD 0.05 putative transport protein, C4-dicarboxylate uptake C family
safA-ydeO 0.05 YdeO DNA-binding transcriptional dual regulator
two-component system connector protein
tolC-ygiABC 0.04 predicted enzyme with ATPase activity
conserved outer membrane protein
predicted protein
TolC outer membrane channel
yneM 0.02 small membrane protein

Network of associatons between targets according to the STRING database.

First level regulatory network of PhoP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106) peptidyl-histidine modification(GO:0018202)
0.1 0.4 GO:0031556 transcriptional attenuation by ribosome(GO:0031556)
0.1 0.2 GO:0009090 homoserine biosynthetic process(GO:0009090) homoserine metabolic process(GO:0009092)
0.1 0.2 GO:0009089 lysine biosynthetic process via diaminopimelate(GO:0009089)
0.0 0.1 GO:0032026 response to magnesium ion(GO:0032026) regulation of response to stimulus(GO:0048583)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043227 membrane-bounded organelle(GO:0043227) intracellular membrane-bounded organelle(GO:0043231)
0.0 0.2 GO:0031230 intrinsic component of cell outer membrane(GO:0031230)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019202 aspartate kinase activity(GO:0004072) amino acid kinase activity(GO:0019202)
0.1 0.4 GO:0019829 cation-transporting ATPase activity(GO:0019829)
0.1 0.2 GO:0003992 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity(GO:0003992)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0051087 chaperone binding(GO:0051087)