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GSE80451: E.coli grown aerobically and anaerobically

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Results for PhoB

Z-value: 0.48

Transcription factors associated with PhoB

Gene Symbol Gene ID Gene Info
phoB
phoB PhoB transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
phoB0.721.7e-01Click!

Activity profile of PhoB motif

Sorted Z-values of PhoB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
ompF 0.77
ompF
outer membrane porin F
cra 0.63
cra
Cra DNA-binding transcriptional dual regulator
psiE 0.55
psiE
predicted phosphate starvation-inducible protein
amn 0.53
amn
AMP nucleosidase
sbcDC 0.45
sbcC
sbcD
ATP dependent, structure specific DNA nuclease - SbcC subunit
ATP dependent, structure specific DNA nuclease - SbcD subunit
asr 0.43
asr
acid shock protein
gadX 0.39
gadX
GadX DNA-binding transcriptional dual regulator
ydfH 0.34
ydfH
YdfH DNA-binding transcriptional repressor
pitB 0.32
pitB
metal phosphate:H+ symporter PitB
gadXW 0.27
gadW
gadX
GadW DNA-binding transcriptional dual regulator
GadX DNA-binding transcriptional dual regulator
pstSCAB-phoU 0.17
pstS
pstC
pstA
phoU
pstB
phosphate ABC transporter - periplasmic binding protein
phosphate ABC transporter - membrane subunit
phosphate ABC transporter - membrane subunit
negative regulator of the pho regulon
phosphate ABC transporter - ATP binding subunit
phoE 0.17
phoE
outer membrane porin E
phoBR 0.17
phoR
phoB
PhoR
PhoB transcriptional dual regulator
argP 0.16
argP
ArgP transcriptional activator
pstSCA 0.10
pstS
pstC
pstA
phosphate ABC transporter - periplasmic binding protein
phosphate ABC transporter - membrane subunit
phosphate ABC transporter - membrane subunit
yhjC 0.09
yhjC
predicted DNA-binding transcriptional regulator
mipA 0.06
mipA
scaffolding protein that interacts with murein polymerase and murein hydrolase
phoU 0.05
phoU
negative regulator of the pho regulon
waaH 0.03
waaH
UDP-glucuronate:LPS(HepIII) glycosyltransferase
cusCFBA 0.03
cusA
cusC
cusB
cusF
copper / silver exporter - membrane subunit
copper / silver exporter - outer membrane porin
copper / silver exporter - membrane fusion protein
copper / silver exporter - periplasmic binding protein and metallochaperone

Network of associatons between targets according to the STRING database.

First level regulatory network of PhoB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0098661 phosphate ion transmembrane transport(GO:0035435) inorganic anion transmembrane transport(GO:0098661)
0.1 0.8 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.5 GO:0010043 response to zinc ion(GO:0010043)
0.1 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174) negative regulation of DNA-dependent DNA replication(GO:2000104)
0.0 0.2 GO:0016036 cellular response to phosphate starvation(GO:0016036)
0.0 0.6 GO:0006096 glycolytic process(GO:0006096)
0.0 0.5 GO:0006281 DNA repair(GO:0006281)
0.0 0.6 GO:0051254 positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of nucleobase-containing compound metabolic process(GO:0045935) positive regulation of RNA metabolic process(GO:0051254) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0022885 bacteriocin transmembrane transporter activity(GO:0022885) colicin transmembrane transporter activity(GO:0042912)
0.2 0.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.7 GO:0001216 transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001140) bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding(GO:0001216)
0.1 0.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 0.2 GO:0001108 basal transcription machinery binding(GO:0001098) bacterial-type RNA polymerase holo enzyme binding(GO:0001108)
0.0 0.2 GO:0003681 bent DNA binding(GO:0003681)
0.0 0.2 GO:0022829 porin activity(GO:0015288) wide pore channel activity(GO:0022829)