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GSE80451: E.coli grown aerobically and anaerobically

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Results for PdhR

Z-value: 0.35

Transcription factors associated with PdhR

Gene Symbol Gene ID Gene Info
pdhR
pdhR PdhR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pdhR-0.276.7e-01Click!

Activity profile of PdhR motif

Sorted Z-values of PdhR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
tomB-hha 0.96
tomB
hha
protein that modulates Hha toxicity
haemolysin expression modulating protein
ndh 0.77
ndh
NADH:quinone oxidoreductase II
hemL 0.58
hemL
glutamate-1-semialdehyde aminotransferase
glcDEFGBA 0.46
glcD
glcE
glcF
glcG
glcA
glcB
glycolate oxidase, predicted FAD-linked subunit
glycolate oxidase, predicted FAD-binding subunit
glycolate oxidase, predicted iron-sulfur subunit
conserved protein
glycolate / lactate:H+ symporter
malate synthase G
fecABCDE 0.29
fecD
fecE
fecB
fecC
fecA
ferric citrate ABC transporter - membrane subunit
ferric citrate ABC transporter - ATP binding subunit
ferric citrate ABC transporter - periplasmic binding protein
ferric citrate ABC transporter - membrane subunit
ferric citrate outer membrane porin FecA

Network of associatons between targets according to the STRING database.

First level regulatory network of PdhR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.5 GO:0046487 primary alcohol metabolic process(GO:0034308) glyoxylate metabolic process(GO:0046487)
0.1 1.1 GO:0055076 transition metal ion homeostasis(GO:0055076)
0.0 1.0 GO:0044010 single-species biofilm formation(GO:0044010)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0043879 glycolate transmembrane transporter activity(GO:0043879) transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0015603 iron chelate transmembrane transporter activity(GO:0015603)
0.0 0.6 GO:0016866 intramolecular transferase activity(GO:0016866)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates