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GSE80451: E.coli grown aerobically and anaerobically

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Results for OxyR

Z-value: 0.46

Transcription factors associated with OxyR

Gene Symbol Gene ID Gene Info
oxyR
oxyR OxyR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
oxyR-0.801.0e-01Click!

Activity profile of OxyR motif

Sorted Z-values of OxyR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
mntH 1.41
mntH
Mn2+ / Fe2+: H+ symporter MntH
dps 0.92
dps
stationary phase nucleoid protein that sequesters iron and protects DNA from damage
sufABCDSE 0.88
sufB
sufC
sufA
sufD
sufE
sufS
SufB component of SufBCD Fe-S cluster scaffold complex
SufC component of SufBCD Fe-S cluster scaffold complex
Fe-S transport protein in Fe-S cluster assembly
SufD component of SufBCD Fe-S cluster scaffold complex
sulfur acceptor for SufS cysteine desulfurase
L-cysteine desulfurase
trxC 0.81
trxC
reduced thioredoxin 2
hemH 0.80
hemH
ferrochelatase
grxA 0.71
grxA
reduced glutaredoxin 1
ychF 0.21
ychF
ribosome-binding ATPase, inhibitor of catalase activity
dsbG 0.10
dsbG
DsbGreduced

Network of associatons between targets according to the STRING database.

First level regulatory network of OxyR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0006824 cobalt ion transport(GO:0006824)
0.2 0.8 GO:0098869 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.9 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.8 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004325 ferrochelatase activity(GO:0004325)
0.2 1.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078) divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.1 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:0004857 enzyme inhibitor activity(GO:0004857)