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GSE80451: E.coli grown aerobically and anaerobically

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Results for MarA

Z-value: 0.52

Transcription factors associated with MarA

Gene Symbol Gene ID Gene Info
marA
marA MarA DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
marA0.306.3e-01Click!
marR0.306.3e-01Click!

Activity profile of MarA motif

Sorted Z-values of MarA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
decR 2.24
decR
DecR DNA-binding transcriptional activator
sodA 1.97
sodA
superoxide dismutase (Mn)
slp-dctR 1.40
slp
dctR
starvation lipoprotein
predicted DNA-binding transcriptional regulator
fumC 0.90
fumC
fumarase C
acnA 0.77
acnA
aconitate hydratase 1
acrZ 0.49
acrZ
small membrane protein that interacts with the AcrAB-TolC multidrug efflux pump
fpr 0.39
fpr
flavodoxin-NADP+ reductase/ferredoxin-NADP+ reductase
poxB 0.30
poxB
pyruvate oxidase
pqiAB 0.25
pqiB
pqiA
paraquat-inducible protein B
paraquat-inducible protein A
inaA 0.05
inaA
pH-inducible protein involved in stress response
zwf 0.03
zwf
glucose-6-phosphate dehydrogenase (NADP+)

Network of associatons between targets according to the STRING database.

First level regulatory network of MarA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0000303 response to superoxide(GO:0000303)
0.5 1.4 GO:0043471 regulation of cellular catabolic process(GO:0031329) regulation of cellular carbohydrate catabolic process(GO:0043471)
0.4 2.2 GO:0043200 response to amino acid(GO:0043200) sulfur compound catabolic process(GO:0044273)
0.3 0.9 GO:0006108 malate metabolic process(GO:0006108)
0.3 0.8 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.5 GO:0036460 cellular response to cell envelope stress(GO:0036460)
0.0 0.3 GO:0006090 pyruvate metabolic process(GO:0006090)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 GO:0019867 outer membrane(GO:0019867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.9 GO:0004333 fumarate hydratase activity(GO:0004333)
0.0 0.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 1.2 GO:0043565 sequence-specific DNA binding(GO:0043565)