ISMARA results: LexA

Project

GSE80451: E.coli grown aerobically and anaerobically

Navigation

Downloads

Results for LexA

Z-value: 1.05

Transcription factors associated with LexA

Gene Symbol	Gene ID	Gene Info
lexA RegulonDB EcoCyc	lexA	LexA DNA-binding transcriptional repressor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
lexA		-0.81	1.0e-01	Click!

Activity profile of LexA motif

Sorted Z-values of LexA motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Gene	Gene Info
dinD Show fit	1.81	dinD RegulonDB EcoCyc Show fit	DNA-damage-inducible protein
symE Show fit	1.57	symE RegulonDB EcoCyc Show fit	toxin-like protein of the SOS response
cho Show fit	1.51	cho RegulonDB EcoCyc Show fit	endonuclease of nucleotide excision repair
ruvAB Show fit	1.48	ruvA RegulonDB EcoCyc Show fit ruvB RegulonDB EcoCyc Show fit	branch migration of Holliday structures; repair branch migration of Holliday structures; repair helicase
recN Show fit	1.34	recN RegulonDB EcoCyc Show fit	protein used in recombination and DNA repair
ybfE Show fit	1.13	ybfE RegulonDB EcoCyc Show fit	LexA-regulated protein
polB Show fit	1.10	polB RegulonDB EcoCyc Show fit	DNA polymerase II
uvrD Show fit	1.00	uvrD RegulonDB EcoCyc Show fit	ssDNA translocase and dsDNA helicase - DNA helicase II
ptrA Show fit	0.77	ptrA RegulonDB EcoCyc Show fit	protease III
dinG Show fit	0.69	dinG RegulonDB EcoCyc Show fit	ATP-dependent helicase

Showing 1 to 10 of 22 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of LexA

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0006289	nucleotide-excision repair(GO:0006289)
0.3	2.0	GO:0006302	double-strand break repair(GO:0006302)
0.1	1.5	GO:0009411	response to UV(GO:0009411)
0.2	1.3	GO:0006402	mRNA catabolic process(GO:0006402)
0.2	1.1	GO:0045005	DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0	0.8	GO:0006508	proteolysis(GO:0006508)
0.2	0.7	GO:0032392	DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.2	0.6	GO:0043462	regulation of ATPase activity(GO:0043462) negative regulation of DNA-dependent DNA replication(GO:2000104)
0.0	0.4	GO:0010165	response to X-ray(GO:0010165)
0.1	0.2	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731) DNA biosynthetic process(GO:0071897)

Showing 1 to 10 of 11 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.8	GO:0009380	excinuclease repair complex(GO:0009380)
0.2	1.5	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.2	0.6	GO:0009338	exodeoxyribonuclease V complex(GO:0009338)
0.1	0.4	GO:0042575	DNA polymerase complex(GO:0042575)

Showing 1 to 4 of 4 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.8	GO:0004003	DNA helicase activity(GO:0003678) ATP-dependent DNA helicase activity(GO:0004003)
0.2	1.5	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.4	1.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2	0.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	0.6	GO:0060590	ATPase regulator activity(GO:0060590)
0.1	0.4	GO:0008094	DNA-dependent ATPase activity(GO:0008094)

Showing 1 to 6 of 6 entries

Results for LexA

Z-value: 1.05

Transcription factors associated with LexA

Activity-expression correlation:

Activity profile of LexA motif

Sorted Z-values of LexA motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of LexA

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: