Project

GSE80451: E.coli grown aerobically and anaerobically

Navigation
Downloads

Results for LexA

Z-value: 1.05

Transcription factors associated with LexA

Gene Symbol Gene ID Gene Info
lexA
lexA LexA DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lexA-0.811.0e-01Click!

Activity profile of LexA motif

Sorted Z-values of LexA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
dinD 1.81
dinD
DNA-damage-inducible protein
symE 1.57
symE
toxin-like protein of the SOS response
cho 1.51
cho
endonuclease of nucleotide excision repair
ruvAB 1.48
ruvA
ruvB
branch migration of Holliday structures; repair
branch migration of Holliday structures; repair helicase
recN 1.34
recN
protein used in recombination and DNA repair
ybfE 1.13
ybfE
LexA-regulated protein
polB 1.10
polB
DNA polymerase II
uvrD 1.00
uvrD
ssDNA translocase and dsDNA helicase - DNA helicase II
ptrA 0.77
ptrA
protease III
dinG 0.69
dinG
ATP-dependent helicase
ptrA-recBD 0.64
recB
recD
ptrA
RecB
RecD
protease III
sbmC 0.57
sbmC
DNA gyrase inhibitor
umuDC 0.41
umuD
umuC
SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC
SOS mutagenesis and repair
uvrA 0.41
uvrA
excision nuclease subunit A
uvrB 0.40
uvrB
DNA repair; excision nuclease subunit B
yebG 0.39
yebG
conserved protein regulated by LexA
molR_1 0.37
molR_1
molybdate metabolism regulator (interrupted)
insK 0.16
insK
IS150 conserved protein InsB
ftsK 0.03
ftsK
essential cell division protein FtsK
dinI 0.03
dinI
DNA damage-inducible protein I
recA 0.02
recA
DNA strand exchange and recombination protein with protease and nuclease activity
recAX 0.00
recX
recA
regulatory protein RecX; inhibitor of RecA
DNA strand exchange and recombination protein with protease and nuclease activity

Network of associatons between targets according to the STRING database.

First level regulatory network of LexA

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0006289 nucleotide-excision repair(GO:0006289)
0.3 2.0 GO:0006302 double-strand break repair(GO:0006302)
0.2 0.7 GO:0032392 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.2 1.1 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.2 0.6 GO:0043462 regulation of ATPase activity(GO:0043462) negative regulation of DNA-dependent DNA replication(GO:2000104)
0.2 1.3 GO:0006402 mRNA catabolic process(GO:0006402)
0.1 1.5 GO:0009411 response to UV(GO:0009411)
0.1 0.2 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731) DNA biosynthetic process(GO:0071897)
0.0 0.4 GO:0010165 response to X-ray(GO:0010165)
0.0 0.8 GO:0006508 proteolysis(GO:0006508)
0.0 0.0 GO:0000920 cell separation after cytokinesis(GO:0000920)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0009380 excinuclease repair complex(GO:0009380)
0.2 0.6 GO:0009338 exodeoxyribonuclease V complex(GO:0009338)
0.2 1.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.4 GO:0042575 DNA polymerase complex(GO:0042575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0004003 DNA helicase activity(GO:0003678) ATP-dependent DNA helicase activity(GO:0004003)
0.4 1.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 1.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.2 0.6 GO:0060590 ATPase regulator activity(GO:0060590)
0.2 0.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.4 GO:0008094 DNA-dependent ATPase activity(GO:0008094)