Project

GSE80451: E.coli grown aerobically and anaerobically

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Results for IclR

Z-value: 0.92

Transcription factors associated with IclR

Gene Symbol Gene ID Gene Info
iclR
iclR IclR transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
iclR0.976.9e-03Click!

Activity profile of IclR motif

Sorted Z-values of IclR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
aceBAK 5.01
aceK
aceB
aceA
isocitrate dehydrogenase phosphatase / isocitrate dehydrogenase kinase
malate synthase A
isocitrate lyase
iclR 3.46
iclR
IclR transcriptional repressor

Network of associatons between targets according to the STRING database.

First level regulatory network of IclR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 3.5 GO:1903507 negative regulation of transcription, DNA-templated(GO:0045892) negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 8.5 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0016208 AMP binding(GO:0016208)
0.0 3.5 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)