Project
GSE80451: E.coli grown aerobically and anaerobically
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Results for CpxR
Z-value: 1.09
Transcription factors associated with CpxR
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| cpxR | 0.92 | 2.6e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| yqaE Show fit | 4.69 |
predicted membrane protein |
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| yqaE-kbp Show fit | 3.63 |
K+ binding protein predicted membrane protein |
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| cpxPQ Show fit | 2.79 |
CpxQ small regulatory RNA CpxP |
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| ldtD Show fit | 2.75 |
L,D-transpeptidase LdtD |
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| tomB-hha Show fit | 1.98 |
protein that modulates Hha toxicity haemolysin expression modulating protein |
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| spy Show fit | 1.87 |
ATP-independent periplasmic chaperone |
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| ompC Show fit | 1.70 |
outer membrane protein C |
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| rpoE-rseABC Show fit | 1.49 |
RNA polymerase, sigma 24 (sigma E) factor rseB protein RseC anti-sigma factor |
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| yebE Show fit | 1.37 |
conserved inner membrane protein |
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| dgcZ Show fit | 1.22 |
diguanylate cyclase |
Network of associatons between targets according to the STRING database.
First level regulatory network of CpxR
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 8.2 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.5 | 3.3 | GO:0030162 | regulation of proteolysis(GO:0030162) |
| 0.6 | 1.9 | GO:0043164 | Gram-negative-bacterium-type cell wall biogenesis(GO:0043164) |
| 0.1 | 1.9 | GO:0010033 | response to organic substance(GO:0010033) |
| 0.4 | 1.7 | GO:0015748 | organophosphate ester transport(GO:0015748) |
| 0.0 | 1.4 | GO:0009266 | response to temperature stimulus(GO:0009266) |
| 0.4 | 1.2 | GO:0010639 | negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209) |
| 0.2 | 0.9 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
| 0.1 | 0.4 | GO:0032978 | protein insertion into membrane from inner side(GO:0032978) |
| 0.0 | 0.1 | GO:0031399 | regulation of protein modification process(GO:0031399) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.9 | GO:0030288 | outer membrane-bounded periplasmic space(GO:0030288) |
| 0.3 | 2.3 | GO:0045203 | integral component of cell outer membrane(GO:0045203) |
| 0.0 | 1.8 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.1 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.5 | 3.6 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.6 | 1.9 | GO:0070004 | cysteine-type peptidase activity(GO:0008234) cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) peptidoglycan L,D-transpeptidase activity(GO:0071972) |
| 0.5 | 1.5 | GO:0045152 | antisigma factor binding(GO:0045152) |
| 0.3 | 1.2 | GO:0052621 | diguanylate cyclase activity(GO:0052621) |
| 0.1 | 0.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.2 | 0.5 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.1 | 0.2 | GO:0050380 | undecaprenyl-diphosphatase activity(GO:0050380) |