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GSE80451: E.coli grown aerobically and anaerobically

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Results for CRP

Z-value: 0.75

Transcription factors associated with CRP

Gene Symbol Gene ID Gene Info
crp
crp CRP transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
crp-0.612.8e-01Click!

Activity profile of CRP motif

Sorted Z-values of CRP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
glnA 0.45
glnA
glutamine synthetase
spf 0.45
spf
Spot42
glpABC 0.30
glpA
glpC
glpB
anaerobic glycerol-3-phosphate dehydrogenase subunit A
anaerobic glycerol-3-phosphate dehydrogenase subunit C
anaerobic glycerol-3-phosphate dehydrogenase subunit B
ykgR 0.24
ykgR
small membrane protein
tnaC 0.23
tnaC
tryptophanase operon leader peptide
ppiA 0.22
ppiA
peptidyl-prolyl cis-trans isomerase A (rotamase A)
bglG 0.21
bglG
BglG transcriptional antiterminator
dctA 0.21
dctA
C4 dicarboxylate / orotate:H+ symporter
rhaSR 0.20
rhaS
rhaR
RhaS transcriptional activator
RhaR transcriptional activator
hofMNOP 0.20
hofM
hofO
hofN
hofP
protein involved in utilization of DNA as a carbon source
protein involved in utilization of DNA as a carbon source
protein involved in utilization of DNA as a carbon source
protein involved in utilization of DNA as a carbon source
argG 0.19
argG
argininosuccinate synthase
ompF 0.18
ompF
outer membrane porin F
yjiY 0.18
yjiY
inner membrane protein - predicted transporter
glpTQ 0.18
glpT
glpQ
glycerol-3-phosphate:phosphate antiporter
glycerophosphoryl diester phosphodiesterase, periplasmic
ompW 0.18
ompW
outer membrane protein W
cpdB 0.16
cpdB
2'3' cyclic nucleotide phosphodiesterase/3' nucleotidase
bglGFB 0.15
bglB
bglG
bglF
6-phospho-β-glucosidase B; cryptic
BglG transcriptional antiterminator
BglF
sdhDAB 0.14
sdhA
sdhB
sdhD
succinate:quinone oxidoreductase, FAD binding protein
succinate:quinone oxidoreductase, iron-sulfur cluster binding protein
succinate:quinone oxidoreductase, membrane protein SdhD
ptsHI-crr 0.14
ptsI
ptsH
crr
PTS enzyme I
HPr
Enzyme IIAGlc; Crr
fumA 0.13
fumA
fumarase A
tsx 0.13
tsx
nucleoside channel; receptor of phage T6 and colicin K
aceBAK 0.13
aceK
aceB
aceA
isocitrate dehydrogenase phosphatase / isocitrate dehydrogenase kinase
malate synthase A
isocitrate lyase
caiF 0.13
caiF
CaiF transcriptional activator
acnB 0.13
acnB
bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase
cyoABCDE 0.12
cyoA
cyoC
cyoB
cyoE
cyoD
cytochrome bo terminal oxidase subunit II
cytochrome bo terminal oxidase subunit III
cytochrome bo terminal oxidase subunit I
heme O synthase
cytochrome bo terminal oxidase subunit IV
uxuAB 0.12
uxuA
uxuB
D-mannonate dehydratase
D-mannonate oxidoreductase
galETK 0.12
galT
galE
galK
galactose-1-phosphate uridylyltransferase
UDP-glucose 4-epimerase
galactokinase
gntT 0.11
gntT
gluconate transporter GntT
cstA 0.11
cstA
peptide transporter induced by carbon starvation
ubiG 0.11
ubiG
bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase
pck 0.11
pck
phosphoenolpyruvate carboxykinase (ATP)
sdhCDAB-sucABCD 0.11
sucA
sucC
sucB
sucD
sdhA
sdhC
sdhB
sdhD
subunit of E1(0) component of 2-oxoglutarate dehydrogenase
succinyl-CoA synthetase, β subunit
dihydrolipoyltranssuccinylase
succinyl-CoA synthetase, α subunit
succinate:quinone oxidoreductase, FAD binding protein
succinate:quinone oxidoreductase, membrane protein SdhC
succinate:quinone oxidoreductase, iron-sulfur cluster binding protein
succinate:quinone oxidoreductase, membrane protein SdhD
galS 0.10
galS
GalS DNA-binding transcriptional dual regulator
dcuR 0.10
dcuR
DcuR transcriptional activator
grpE 0.10
grpE
nucleotide exchange factor
cytR 0.10
cytR
CytR DNA-binding transcriptional repressor
yhfA 0.10
yhfA
conserved protein
gcvTHP 0.10
gcvH
gcvP
gcvT
glycine cleavage system H protein
glycine decarboxylase
aminomethyltransferase
glnALG 0.10
glnL
glnA
glnG
NtrB
glutamine synthetase
NtrC transcriptional dual regulator
uxaCA 0.10
uxaA
uxaC
D-altronate dehydratase
D-glucuronate isomerase/D-galacturonate isomerase
yiaJ 0.10
yiaJ
YiaJ DNA-binding transcriptional repressor
fucAO 0.09
fucO
fucA
L-1,2-propanediol oxidoreductase
L-fuculose-phosphate aldolase
csgDEFG 0.09
csgG
csgF
csgE
csgD
curli secretion channel
curli assembly component
curli transport specificity factor
CsgD DNA-binding transcriptional dual regulator
chiP-ybfN 0.09
chiP
ybfN
chitobiose outer membrane channel
predicted lipoprotein
tdcABCDEFG 0.09
tdcE
tdcD
tdcG
tdcF
tdcA
tdcC
tdcB
2-ketobutyrate formate-lyase/pyruvate formate-lyase 4, inactive
propionate kinase
L-serine deaminase III
predicted enamine/imine deaminase
TdcA DNA-binding transcriptional activator
serine / threonine:H+ symporter TdcC
catabolic threonine dehydratase
relA-mazEF 0.09
mazE
relA
mazF
MazE antitoxin of the MazF-MazE toxin-antitoxin system
GDP pyrophosphokinase/GTP pyrophosphokinase
MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activity
araBAD 0.09
araB
araA
araD
L-ribulokinase
L-arabinose isomerase
L-ribulose 5-phosphate 4-epimerase
malT 0.08
malT
MalT transcriptional activator
acs-yjcH-actP 0.08
acs
actP
yjcH
acetyl-CoA synthetase (AMP-forming)
acetate / glycolate : cation symporter
conserved inner membrane protein
mpl 0.08
mpl
UDP-N-acetylmuramate:L-alanyl-γ-D-glutamyl-meso-diaminoheptanedioate-D-alanine ligase/UDP-N-acetylmuramate:L-alanyl-γ-D-glutamyl-meso-diaminopimelate ligase
putP 0.08
putP
proline:Na+ symporter
glgCAP 0.08
glgP
glgA
glgC
glycogen phosphorylase
glycogen synthase
glucose-1-phosphate adenylyltransferase
mlc 0.08
mlc
Mlc DNA-binding transcriptional repressor
paaABCDEFGHIJK 0.07
paaB
paaC
paaA
paaF
paaG
paaD
paaE
paaJ
paaK
paaH
paaI
ring 1,2-phenylacetyl-CoA epoxidase subunit
ring 1,2-phenylacetyl-CoA epoxidase, structural subunit
ring 1,2-phenylacetyl-CoA epoxidase, monooxygenase subunit
predicted 2,3-dehydroadipyl-CoA hydratase
predicted ring 1,2-epoxyphenylacetyl-CoA isomerase (oxepin-CoA forming)
phenylacetate degradation protein
ring 1,2-phenylacetyl-CoA epoxidase, reductase subunit
β-ketoadipyl-CoA thiolase
phenylacetate-CoA ligase
3-hydroxyadipyl-CoA dehydrogenase (NAD+)
phenylacetyl-CoA thioesterase
entCEBAH 0.07
entA
entH
entC
entB
entE
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
proofreading thioesterase in enterobactin biosynthesis
isochorismate synthase 1
EntB
2,3-dihydroxybenzoate-AMP ligase
malI 0.07
malI
MalI DNA-binding transcriptional repressor
fucPIKUR 0.07
fucU
fucR
fucK
fucP
fucI
L-fucose mutarotase
FucR transcriptional activator
L-fuculokinase
fucose:H+ symporter
L-fucose isomerase
mlc-ynfK 0.07
mlc
ynfK
Mlc DNA-binding transcriptional repressor
predicted dethiobiotin synthetase
aldA 0.07
aldA
aldehyde dehydrogenase A
mglBAC 0.07
mglA
mglB
mglC
D-galactose / D-galactoside ABC transporter - ATP binding subunit
D-galactose / D-galactoside ABC transporter - periplasmic binding protein
D-galactose / D-galactoside ABC transporter - membrane subunit
idnDOTR 0.07
idnD
idnO
idnR
idnT
L-idonate 5-dehydrogenase
5-keto-D-gluconate 5-reductase
IdnR transcriptional regulator
L-idonate / 5-ketogluconate / gluconate transporter IdnT
gntP 0.07
gntP
gluconate / fructuronate transporter GntP
yeiW 0.07
yeiW
conserved protein
narQ 0.07
narQ
NarQ
araE-ygeA 0.07
ygeA
araE
predicted racemase
arabinose:H+ symporter
murQP 0.06
murP
murQ
N-acetylmuramic acid PTS permease / anhydro-N-acetylmuramic acid permease
N-acetylmuramic acid 6-phosphate etherase
gltA 0.06
gltA
citrate synthase
treBC 0.06
treC
treB
trehalose-6-phosphate hydrolase
trehalose PTS permease - TreB subunit
grcA 0.06
grcA
stress-induced alternate pyruvate formate-lyase subunit
ampDE 0.06
ampD
ampE
N-acetyl-anhydromuramyl-L-alanine amidase
inner membrane protein
araE 0.06
araE
arabinose:H+ symporter
glcC 0.06
glcC
GlcC transcriptional dual regulator
glpFKX 0.06
glpF
glpX
glpK
glycerol channel GlpF
fructose 1,6-bisphosphatase II
glycerol kinase
mhpR-lacI 0.06
mhpR
lacI
MhpR transcriptional activator
LacI DNA-binding transcriptional repressor
araFGH 0.06
araF
araG
araH
arabinose ABC transporter - periplasmic binding protein
arabinose ABC transporter - ATP binding subunit
arabinose ABC transporter - membrane subunit
puuDRCBE 0.06
puuR
puuC
puuB
puuD
puuE
PuuR DNA-binding transcriptional repressor
γ-glutamyl-γ-aminobutyraldehyde dehydrogenase
γ-glutamylputrescine oxidase
γ-glutamyl-γ-aminobutyrate hydrolase
4-aminobutyrate aminotransferase
galETKM 0.06
galT
galE
galM
galK
galactose-1-phosphate uridylyltransferase
UDP-glucose 4-epimerase
galactose-1-epimerase
galactokinase
pdhR-aceEF-lpd 0.06
pdhR
lpd
aceF
aceE
PdhR DNA-binding transcriptional dual regulator
lipoamide dehydrogenase
pyruvate dehydrogenase, E2 subunit
subunit of E1p component of pyruvate dehydrogenase complex
flhDC 0.06
flhC
flhD
FlhC transcriptional dual regulator
FlhD transcriptional dual regulator
oxyR 0.05
oxyR
OxyR DNA-binding transcriptional dual regulator
ppdD-hofBC 0.05
ppdD
hofC
hofB
prepilin peptidase dependent protein
inner membrane protein HofC
T2SSE family protein
rhaT 0.05
rhaT
rhamnose / lyxose:H+ symporter
tnaCAB 0.05
tnaA
tnaC
tnaB
tryptophanase
tryptophanase operon leader peptide
tryptophan:H+ symporter TnaB
yiaKLMNO-lyxK-sgbHUE 0.05
lyxK
sgbH
sgbE
sgbU
yiaK
yiaM
yiaL
yiaO
yiaN
L-xylulose kinase
3-keto-L-gulonate 6-phosphate decarboxylase
L-ribulose-5-phosphate 4-epimerase
predicted L-xylulose 5-phosphate 3-epimerase
2,3-diketo-L-gulonate reductase
2,3-diketo-L-gulonate:Na+ symporter - membrane subunit
conserved protein
2,3-diketo-L-gulonate:Na+ symporter - periplasmic binding protein
2,3-diketo-L-gulonate:Na+ symporter - membrane subunit
mdh 0.05
mdh
malate dehydrogenase
pncB 0.05
pncB
nicotinate phosphoribosyltransferase
ychH 0.05
ychH
stress-induced protein
fiu 0.05
fiu
putative outer membrane receptor for iron transport
patZ 0.05
patZ
peptidyl-lysine acetyltransferase
gntX-nfuA 0.05
gntX
nfuA
protein involved in utilization of DNA as a carbon source
iron-sulfur cluster scaffold protein
yeiP 0.04
yeiP
predicted dehydrogenase, NAD-dependent
preTA 0.04
preT
preA
NADH-dependent dihydropyrimidine dehydrogenase subunit
NADH-dependent dihydropyrimidine dehydrogenase subunit
melR 0.04
melR
MelR DNA-binding transcriptional dual regulator
ybiT 0.04
ybiT
putative transport protein, ABC superfamily - ATP binding component
galP 0.04
galP
galactose:H+ symporter
araC 0.04
araC
AraC DNA-binding transcriptional dual regulator
csiD-lhgO-gabDTP 0.04
gabD
lhgO
gabP
csiD
gabT
succinate-semialdehyde dehydrogenase (NADP+)
L-2-hydroxyglutarate oxidase
4-aminobutyrate:H+ symporter
predicted protein
4-aminobutyrate aminotransferase
dcuB-fumB 0.04
fumB
dcuB
fumarase B
dicarboxylate transporter DcuB
hupA 0.04
hupA
transcriptional dual regulator HU-α (HU-2)
modABC 0.04
modA
modB
modC
molybdate ABC transporter - periplasmic binding protein
molybdate ABC transporter - membrane subunit
molybdate ABC transporter - ATP binding subunit
ascFB 0.04
ascF
ascB
β-glucoside PTS permease AscF (cryptic)
6-phospho-β-glucosidase AscB
sbmC 0.04
sbmC
DNA gyrase inhibitor
comR 0.04
comR
ComR DNA-binding transcriptional repressor
gdhA 0.03
gdhA
glutamate dehydrogenase
glpD 0.03
glpD
glycerol-3-phosphate dehydrogenase, aerobic
dpiBA 0.03
dpiB
dpiA
DpiB sensory histidine kinase
DpiA transcriptional dual regulator
gntKU 0.03
gntK
gntU
D-gluconate kinase, thermostable
gluconate transporter GntU
speC 0.03
speC
ornithine decarboxylase, biosynthetic
rpoS 0.03
rpoS
RNA polymerase, sigma S (sigma 38) factor
serC-aroA 0.03
aroA
3-phosphoshikimate-1-carboxyvinyltransferase
malEFG 0.03
malF
malG
malE
maltose ABC transporter - membrane subunit
maltose ABC transporter - membrane subunit
maltose ABC transporter - periplasmic binding protein
fepA-entD 0.03
fepA
entD
ferric enterobactin / colicin B / colicin D outer membrane porin FepA
phosphopantetheinyl transferase/phosphopantetheinyl transferase
ldtB 0.03
ldtB
L,D-transpeptidase YbiS
serC 0.03

gltBDF 0.03
gltB
gltD
gltF
glutamate synthase, large subunit
glutamate synthase, small subunit
periplasmic protein
gntK 0.02
gntK
D-gluconate kinase, thermostable
mhpABCDFE 0.02
mhpC
mhpB
mhpA
mhpF
mhpE
mhpD
2-hydroxy-6-ketonona-2,4-dienedioate hydrolase
2,3-dihydroxyphenylpropionate 1,2-dioxygenase
3-(3-hydroxyphenyl)propionate 2-hydroxylase
acetaldehyde dehydrogenase (acylating)
4-hydroxy-2-ketovalerate aldolase
2-hydroxypentadienoate hydratase
melAB 0.02
melB
melA
melibiose:H+/Na+/Li+ symporter
α-galactosidase
glpEGR 0.02
glpE
glpG
glpR
thiosulfate sulfurtransferase
intramembrane serine protease GlpG
GlpR DNA-binding transcriptional repressor
uhpT 0.02
uhpT
hexose-6-phosphate:phosphate antiporter
malK-lamB-malM 0.02
lamB
malM
malK
maltose outer membrane porin / phage lambda receptor protein
maltose regulon periplasmic protein
maltose ABC transporter - ATP binding subunit
xylFGHR 0.02
xylH
xylR
xylG
xylF
xylose ABC transporter - membrane subunit
XylR transcriptional dual regulator
xylose ABC transporter - ATP binding subunit
xylose ABC transporter - periplasmic binding protein
uidABC 0.01
uidB
uidC
uidA
glucuronide:H+ symporter
outer membrane-associated protein
β-D-glucuronidase
hyfABCDEFGHIJR-focB 0.01
hyfJ
hyfI
hyfH
hyfC
hyfB
hyfA
hyfG
hyfF
hyfE
hyfD
hyfR
focB
hydrogenase 4 component J, putative protein processing element
hydrogenase 4, small subunit
hydrogenase 4, component H
hydrogenase 4, component C
hydrogenase 4, component B
hydrogenase 4, component A
hydrogenase 4, large subunit
hydrogenase 4, component F
hydrogenase 4, component E
hydrogenase 4, component D
HyfR DNA-binding transcriptional activator
FocB formate FNT transporter
ulaABCDEF 0.01
ulaD
ulaE
ulaF
ulaA
ulaB
ulaC
3-keto-L-gulonate 6-phosphate decarboxylase
L-xylulose 5-phosphate 3-epimerase
L-ribulose 5-phosphate 4-epimerase
L-ascorbate PTS permease - UlaA subunit
L-ascorbate PTS permease - UlaB subunit
L-ascorbate PTS permease - UlaC subunit
aldB 0.01
aldB
acetaldehyde dehydrogenase
nanATEK-yhcH 0.01
nanA
nanK
nanE
nanT
yhcH
N-acetylneuraminate lyase
N-acetylmannosamine kinase
predicted N-acetylmannosamine-6-phosphate epimerase
N-acetylneuraminate:H+ symporter
conserved protein
dsdA 0.01
dsdA
D-serine ammonia-lyase
aer 0.01
aer
aerotaxis sensor receptor, flavoprotein
caiTABCDE 0.01
caiT
caiE
caiD
caiC
caiB
caiA
L-carnitine : γ-butyrobetaine antiporter
predicted acyl transferase
crotonobetainyl-CoA hydratase
carnitine-CoA ligase
γ-butyrobetainyl-CoA:carnitine CoA transferase
crotonobetainyl-CoA reductase
rpsF-priB-rpsR-rplI 0.01
rpsF
priB
rpsR
rplI
30S ribosomal subunit protein S6
primosomal replication protein N
30S ribosomal subunit protein S18
50S ribosomal subunit protein L9
gyrA 0.00
gyrA
DNA gyrase, subunit A
ugpBAECQ 0.00
ugpE
ugpA
ugpB
ugpC
ugpQ
glycerol-3-phosphate ABC transporter - membrane subunit
glycerol-3-phosphate ABC transporter - membrane subunit
glycerol-3-phosphate ABC transporter - periplasmic binding protein
glycerol-3-phosphate ABC transporter - ATP binding subunit
glycerophosphodiester phosphodiesterase, cytosolic
mcaS 0.00
mcaS
IsrA
fumAC 0.00
fumA
fumC
fumarase A
fumarase C
aspA-dcuA 0.00
aspA
dcuA
aspartate ammonia-lyase
dicarboxylate transporter DcuA
aspA 0.00
aspA
aspartate ammonia-lyase
hpt 0.00
hpt
hypoxanthine-guanine phosphoribosyltransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of CRP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.2 GO:0015976 carbon utilization(GO:0015976)
0.1 0.3 GO:0019566 arabinose metabolic process(GO:0019566) arabinose catabolic process(GO:0019568)
0.1 0.3 GO:0090357 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238) regulation of tryptophan metabolic process(GO:0090357)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.1 GO:0015756 fucose transport(GO:0015756)
0.1 0.2 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 0.7 GO:0022900 electron transport chain(GO:0022900)
0.1 0.1 GO:0042882 L-arabinose transport(GO:0042882)
0.1 0.2 GO:0042873 aldonate transport(GO:0042873)
0.1 0.2 GO:0015748 organophosphate ester transport(GO:0015748)
0.1 0.2 GO:0019464 glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0010906 regulation of glucose metabolic process(GO:0010906) regulation of cellular catabolic process(GO:0031329) regulation of cellular carbohydrate catabolic process(GO:0043471) negative regulation of carbohydrate metabolic process(GO:0045912)
0.0 0.1 GO:0006063 uronic acid metabolic process(GO:0006063)
0.0 0.1 GO:0044409 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.1 GO:0018394 peptidyl-lysine acetylation(GO:0018394)
0.0 0.1 GO:0015757 galactose transport(GO:0015757)
0.0 0.2 GO:0006835 dicarboxylic acid transport(GO:0006835) C4-dicarboxylate transport(GO:0015740)
0.0 0.1 GO:0042355 fucose metabolic process(GO:0006004) fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:1902170 cellular response to nitrogen compound(GO:1901699) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.1 GO:0019290 siderophore metabolic process(GO:0009237) enterobactin metabolic process(GO:0009238) enterobactin biosynthetic process(GO:0009239) catechol-containing compound metabolic process(GO:0009712) catechol-containing compound biosynthetic process(GO:0009713) nonribosomal peptide biosynthetic process(GO:0019184) siderophore biosynthetic process(GO:0019290) siderophore biosynthetic process from catechol(GO:0019540) phenol-containing compound biosynthetic process(GO:0046189)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.1 GO:0034661 guanosine tetraphosphate metabolic process(GO:0015969) purine ribonucleoside bisphosphate metabolic process(GO:0034035) ncRNA catabolic process(GO:0034661)
0.0 0.1 GO:0009254 peptidoglycan turnover(GO:0009254)
0.0 0.0 GO:0019748 secondary metabolic process(GO:0019748)
0.0 0.1 GO:0019319 gluconeogenesis(GO:0006094) hexose biosynthetic process(GO:0019319)
0.0 0.1 GO:0005993 trehalose catabolic process(GO:0005993)
0.0 0.0 GO:0015765 methylgalactoside transport(GO:0015765)
0.0 0.1 GO:0005978 glycogen biosynthetic process(GO:0005978)
0.0 0.1 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.1 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.0 GO:2000104 negative regulation of DNA-dependent DNA replication(GO:2000104)
0.0 0.1 GO:0072350 tricarboxylic acid metabolic process(GO:0072350)
0.0 0.0 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.0 GO:0042884 microcin transport(GO:0042884)
0.0 0.0 GO:0015750 pentose transport(GO:0015750)
0.0 0.1 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012) galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.2 GO:2000142 regulation of DNA-templated transcription, initiation(GO:2000142)
0.0 0.3 GO:0031669 cellular response to nutrient levels(GO:0031669)
0.0 0.0 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.0 GO:0071310 cellular response to organic substance(GO:0071310)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.0 GO:0046417 chorismate metabolic process(GO:0046417)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045273 respiratory chain complex II(GO:0045273) plasma membrane respiratory chain complex II(GO:0045274)
0.1 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.0 GO:0009295 nucleoid(GO:0009295)
0.0 0.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0031246 intrinsic component of periplasmic side of cell outer membrane(GO:0031246)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016211 ammonia ligase activity(GO:0016211)
0.1 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 0.2 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.2 GO:0016208 AMP binding(GO:0016208)
0.1 0.2 GO:0015150 fucose transmembrane transporter activity(GO:0015150)
0.1 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.1 GO:0015147 L-arabinose transmembrane transporter activity(GO:0015147)
0.1 0.3 GO:0042879 gluconate transmembrane transporter activity(GO:0015128) aldonate transmembrane transporter activity(GO:0042879)
0.0 0.2 GO:0015556 dicarboxylic acid transmembrane transporter activity(GO:0005310) fumarate transmembrane transporter activity(GO:0015138) succinate transmembrane transporter activity(GO:0015141) C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.1 GO:0016289 CoA hydrolase activity(GO:0016289) thiolester hydrolase activity(GO:0016790)
0.0 0.1 GO:0008742 L-ribulose-phosphate 4-epimerase activity(GO:0008742)
0.0 0.1 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.1 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.1 GO:0008108 galactokinase activity(GO:0004335) UDP-glucose:hexose-1-phosphate uridylyltransferase activity(GO:0008108)
0.0 0.1 GO:0022885 bacteriocin transmembrane transporter activity(GO:0022885) colicin transmembrane transporter activity(GO:0042912)
0.0 0.1 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.0 0.1 GO:0004777 succinate-semialdehyde dehydrogenase (NAD+) activity(GO:0004777)
0.0 0.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.1 GO:0008706 6-phospho-beta-glucosidase activity(GO:0008706)
0.0 0.2 GO:0031405 lipoic acid binding(GO:0031405)
0.0 0.1 GO:0008893 GTP diphosphokinase activity(GO:0008728) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity(GO:0008893) diphosphoric monoester hydrolase activity(GO:0016794)
0.0 0.1 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867)
0.0 0.1 GO:0005543 phospholipid binding(GO:0005543) O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0015081 sodium ion transmembrane transporter activity(GO:0015081)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.0 GO:0043211 carbohydrate-transporting ATPase activity(GO:0043211)
0.0 0.1 GO:0004333 fumarate hydratase activity(GO:0004333)
0.0 0.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0015927 trehalase activity(GO:0015927)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.0 GO:0015146 pentose transmembrane transporter activity(GO:0015146)
0.0 0.1 GO:0001141 transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001141) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0001131 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001131)
0.0 0.2 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.1 GO:0001159 bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.4 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION Genes involved in Platelet activation, signaling and aggregation
0.1 0.2 REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.0 0.1 REACTOME DEVELOPMENTAL BIOLOGY Genes involved in Developmental Biology