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GSE80451: E.coli grown aerobically and anaerobically

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Results for ArgR

Z-value: 3.60

Transcription factors associated with ArgR

Gene Symbol Gene ID Gene Info
argR
argR ArgR transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
argR-0.975.4e-03Click!

Activity profile of ArgR motif

Sorted Z-values of ArgR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
artJ 25.78
artJ
L-arginine ABC transporter - periplasmic binding protein
argI 19.27
argI
ornithine carbamoyltransferase chain I
argA 16.86
argA
N-acetylglutamate synthase
argCBH 16.21
argH
argB
argC
argininosuccinate lyase
acetylglutamate kinase
N-acetylglutamylphosphate reductase
argG 10.73
argG
argininosuccinate synthase
argD 9.07
argD
N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase
artPIQM 8.08
artQ
artP
artI
artM
L-arginine ABC transporter - membrane subunit
L-arginine ABC transporter - ATP binding subunit
periplasmic binding protein ArtI
L-arginine ABC transporter - membrane subunit
carAB 6.69
carB
carA
carbamoyl phosphate synthetase, β chain
carbamoyl phosphate synthetase, α chain
gltBDF 6.06
gltB
gltD
gltF
glutamate synthase, large subunit
glutamate synthase, small subunit
periplasmic protein
hisJQMP 3.20
hisM
hisP
hisQ
hisJ
lysine/arginine/ornithine ABC transporter / histidine ABC transporter - membrane subunit
lysine / arginine / ornithine ABC transporter / histidine ABC transporter - ATP binding subunit
lysine / arginine / ornithine ABC transporter / histidine ABC transporter - membrane subunit
histidine ABC transporter - periplasmic binding protein
argE 2.97
argE
acetylornithine deacetylase
metY 1.31
metY
tRNAfMet2

Network of associatons between targets according to the STRING database.

First level regulatory network of ArgR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 37.1 GO:1903400 L-arginine import(GO:0043091) L-amino acid import(GO:0043092) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine import into cell(GO:1902765) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
4.9 43.8 GO:0006526 arginine biosynthetic process(GO:0006526)
3.0 6.1 GO:0009084 glutamine family amino acid biosynthetic process(GO:0009084)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.1 GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)
0.4 35.0 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)
0.1 6.7 GO:1902494 catalytic complex(GO:1902494)
0.0 22.0 GO:0005737 cytoplasm(GO:0005737)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
5.4 16.2 GO:0016842 amidine-lyase activity(GO:0016842)
2.8 16.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
2.7 8.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
2.5 35.7 GO:0016597 amino acid binding(GO:0016597)
1.0 6.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
1.0 3.0 GO:0050897 cobalt ion binding(GO:0050897)
0.4 10.7 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)