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GSE67402: E.coli regulatory changes under long-term starvation

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Results for OxyR

Z-value: 0.88

Transcription factors associated with OxyR

Gene Symbol Gene ID Gene Info
oxyR
oxyR OxyR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
oxyR-0.581.6e-03Click!

Activity profile of OxyR motif

Sorted Z-values of OxyR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
oxyS 8.72
oxyS
OxyS
gntP 7.50
gntP
gluconate / fructuronate transporter GntP
yhjA 5.90
yhjA
predicted cytochrome C peroxidase
trxC 5.55
trxC
reduced thioredoxin 2
hcp-hcr 5.14
hcr
hcp
NADH oxidoreductase
hybrid-cluster protein
mntH 4.76
mntH
Mn2+ / Fe2+: H+ symporter MntH
fhuF 4.66
fhuF
hydroxamate siderophore iron reductase
hemH 3.23
hemH
ferrochelatase
sufABCDSE 2.49
sufB
sufC
sufA
sufD
sufE
sufS
SufB component of SufBCD Fe-S cluster scaffold complex
SufC component of SufBCD Fe-S cluster scaffold complex
Fe-S transport protein in Fe-S cluster assembly
SufD component of SufBCD Fe-S cluster scaffold complex
sulfur acceptor for SufS cysteine desulfurase
L-cysteine desulfurase
grxA 2.29
grxA
reduced glutaredoxin 1
uxuAB 1.97
uxuA
uxuB
D-mannonate dehydratase
D-mannonate oxidoreductase
isrC-flu 1.77
isrC
flu
IsrC
CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0042873 aldonate transport(GO:0042873)
1.7 5.1 GO:0046209 nitric oxide metabolic process(GO:0046209) nitric oxide catabolic process(GO:0046210)
1.6 4.8 GO:0006824 cobalt ion transport(GO:0006824)
1.1 5.6 GO:0098869 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.7 2.0 GO:0006063 uronic acid metabolic process(GO:0006063)
0.5 3.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.5 4.6 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.4 2.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 18.2 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.8 GO:0009279 cell outer membrane(GO:0009279)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.5 GO:0042879 gluconate transmembrane transporter activity(GO:0015128) aldonate transmembrane transporter activity(GO:0042879)
1.1 3.2 GO:0004325 ferrochelatase activity(GO:0004325)
0.7 12.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.5 4.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078) divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.4 5.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.0 GO:0008198 ferrous iron binding(GO:0008198)