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GSE67402: E.coli regulatory changes under long-term starvation

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Results for NanR

Z-value: 2.22

Transcription factors associated with NanR

Gene Symbol Gene ID Gene Info
nanR
nanR NanR DNA-binding transcriptional dual regulator

Activity profile of NanR motif

Sorted Z-values of NanR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
nanA 66.95
nanA
N-acetylneuraminate lyase
nanATEK-yhcH 58.32
nanA
nanK
nanE
nanT
yhcH
N-acetylneuraminate lyase
N-acetylmannosamine kinase
predicted N-acetylmannosamine-6-phosphate epimerase
N-acetylneuraminate:H+ symporter
conserved protein
yjhBC 30.17
yjhC
yjhB
KpLE2 phage-like element; predicted oxidoreductase
putative transport protein, major facilitator superfamily
nanCMS 18.61
nanC
nanM
nanS
N-acetylneuraminic acid outer membrane channel
N-acetylneuraminate mutarotase
probable 9-O-acetyl-N-acetylneuraminate esterase
nanCM 18.09
nanC
nanM
N-acetylneuraminic acid outer membrane channel
N-acetylneuraminate mutarotase

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
31.3 125.3 GO:0019262 N-acetylneuraminate metabolic process(GO:0006054) N-acetylneuraminate catabolic process(GO:0019262)
5.0 30.2 GO:0015992 hydrogen transport(GO:0006818) proton transport(GO:0015992)
3.3 36.7 GO:0015772 oligosaccharide transport(GO:0015772)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 36.7 GO:0045203 integral component of cell outer membrane(GO:0045203)
0.3 58.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 30.2 GO:0005886 plasma membrane(GO:0005886)
0.2 67.0 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
31.7 95.0 GO:0015136 sialic acid transmembrane transporter activity(GO:0015136)
8.4 67.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.7 30.2 GO:0005342 organic acid transmembrane transporter activity(GO:0005342) carboxylic acid transmembrane transporter activity(GO:0046943)