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GSE67402: E.coli regulatory changes under long-term starvation

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Results for MprA

Z-value: 0.75

Transcription factors associated with MprA

Gene Symbol Gene ID Gene Info
mprA MprA DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mprA0.927.7e-12Click!

Activity profile of MprA motif

Sorted Z-values of MprA motif

Promoter Log-likelihood Transcript Gene Gene Info
nmpC 9.23 outer membrane porin protein; locus of qsr prophage
acrAB 9.18 AcrAB-TolC multidrug efflux pump - permease subunit
AcrAB-TolC multidrug efflux pump - membrane fusion protein
mprA-emrAB 7.96 MprA DNA-binding transcriptional repressor
EmrAB-TolC multidrug efflux pump - membrane fusion protein
EmrAB-TolC multidrug efflux pump - membrane subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of MprA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.2 GO:0006855 drug transmembrane transport(GO:0006855)
0.3 8.0 GO:0046677 response to antibiotic(GO:0046677)
0.0 9.2 GO:0006810 transport(GO:0006810)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.0 GO:0031237 intrinsic component of periplasmic side of plasma membrane(GO:0031237)
0.2 9.2 GO:1902495 transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351)
0.2 9.2 GO:0009279 cell outer membrane(GO:0009279)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.7 9.2 GO:0015288 porin activity(GO:0015288) wide pore channel activity(GO:0022829)
0.1 8.0 GO:0003677 DNA binding(GO:0003677)