Project

GSE67402: E.coli regulatory changes under long-term starvation

Navigation
Downloads

Results for MarA

Z-value: 0.59

Transcription factors associated with MarA

Gene Symbol Gene ID Gene Info
marA
marA MarA DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
marR0.242.2e-01Click!
marA0.242.2e-01Click!

Activity profile of MarA motif

Sorted Z-values of MarA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
decR 5.81
decR
DecR DNA-binding transcriptional activator
tolC-ygiABC 5.38
ygiC
ygiB
ygiA
tolC
predicted enzyme with ATPase activity
conserved outer membrane protein
predicted protein
TolC outer membrane channel
fpr 2.97
fpr
flavodoxin-NADP+ reductase/ferredoxin-NADP+ reductase
purA 2.58
purA
adenylosuccinate synthetase
marRAB 2.57
marB
marA
marR
multiple antibiotic resistance protein
MarA DNA-binding transcriptional dual regulator
MarR DNA-binding transcriptional repressor
slp-dctR 1.91
slp
dctR
starvation lipoprotein
predicted DNA-binding transcriptional regulator
putA 1.34
putA
fused PutA transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase
hdeAB-yhiD 1.33
yhiD
hdeB
hdeA
inner membrane protein YhiD
HdeB monomer
HdeA monomer, chaperone active form
sodA 1.13
sodA
superoxide dismutase (Mn)
ybjC-nfsA-rimK-ybjN 0.70
nfsA
ybjN
ybjC
rimK
NADPH nitroreductase NfsA
predicted oxidoreductase
predicted inner membrane protein
ribosomal protein S6 modification protein
acrAB 0.67
acrB
acrA
AcrAB-TolC multidrug efflux pump - permease subunit
AcrAB-TolC multidrug efflux pump - membrane fusion protein
zwf 0.41
zwf
glucose-6-phosphate dehydrogenase (NADP+)
poxB 0.38
poxB
pyruvate oxidase
nfsB 0.23
nfsB
NAD(P)H nitroreductase NfsB
pqiAB 0.17
pqiB
pqiA
paraquat-inducible protein B
paraquat-inducible protein A

Network of associatons between targets according to the STRING database.

First level regulatory network of MarA

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0000303 response to superoxide(GO:0000303)
1.2 5.8 GO:0044273 response to amino acid(GO:0043200) sulfur compound catabolic process(GO:0044273)
0.9 5.4 GO:0015891 siderophore transport(GO:0015891)
0.6 2.6 GO:0046040 IMP metabolic process(GO:0046040)
0.6 1.9 GO:0031329 regulation of cellular catabolic process(GO:0031329) regulation of cellular carbohydrate catabolic process(GO:0043471)
0.3 2.6 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.3 1.3 GO:0009065 glutamine family amino acid catabolic process(GO:0009065)
0.3 1.3 GO:0071468 cellular response to pH(GO:0071467) cellular response to acidic pH(GO:0071468)
0.2 0.7 GO:0097305 negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) post-translational protein modification(GO:0043687) response to alcohol(GO:0097305) regulation of single-species biofilm formation on inanimate substrate(GO:1900231) negative regulation of single-species biofilm formation on inanimate substrate(GO:1900232) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209)
0.1 0.4 GO:0009372 quorum sensing(GO:0009372)
0.1 0.2 GO:0046256 trinitrotoluene metabolic process(GO:0018973) 2,4,6-trinitrotoluene metabolic process(GO:0018974) nitrotoluene metabolic process(GO:0019326) 2,4,6-trinitrotoluene catabolic process(GO:0046256) trinitrotoluene catabolic process(GO:0046260) nitrotoluene catabolic process(GO:0046263) toluene-containing compound metabolic process(GO:0072490) toluene-containing compound catabolic process(GO:0072491)
0.1 0.7 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.4 GO:0051262 pyruvate metabolic process(GO:0006090) protein tetramerization(GO:0051262) protein homotetramerization(GO:0051289)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 GO:1902495 transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351)
0.1 1.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.1 4.0 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)
0.0 12.4 GO:0005829 cytosol(GO:0005829)
0.0 0.4 GO:0019867 outer membrane(GO:0019867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.6 2.6 GO:0001067 regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.4 1.3 GO:0051087 chaperone binding(GO:0051087)
0.4 1.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 1.3 GO:0001217 transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001141) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 3.0 GO:0071949 FAD binding(GO:0071949)
0.2 0.7 GO:0034567 chromate reductase activity(GO:0034567)
0.2 0.7 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 2.6 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.1 5.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 2.3 GO:0042802 identical protein binding(GO:0042802)