Project

GSE67402: E.coli regulatory changes under long-term starvation

Navigation
Downloads

Results for Lrp

Z-value: 0.58

Transcription factors associated with Lrp

Gene Symbol Gene ID Gene Info
lrp
lrp Lrp transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lrp0.232.6e-01Click!

Activity profile of Lrp motif

Sorted Z-values of Lrp motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
ilvIH 2.94
ilvI
ilvH
acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit
acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit
livJ 2.52
livJ
branched chain amino acid / phenylalanine ABC transporter - periplasmic binding protein
lrp 2.46
lrp
Lrp transcriptional dual regulator
serC-aroA 2.35
aroA
3-phosphoshikimate-1-carboxyvinyltransferase
gltBDF 2.17
gltB
gltD
gltF
glutamate synthase, large subunit
glutamate synthase, small subunit
periplasmic protein
serC 2.06

livKHMGF 1.92
livG
livF
livM
livK
livH
branched chain amino acid / phenylalanine ABC transporter - ATP binding subunit
branched chain amino acid / phenylalanine ABC transporter - ATP binding subunit
branched chain amino acid / phenylalanine ABC transporter - membrane subunit
L-leucine / L-phenylalanine ABC transporter - periplasmic binding protein
branched chain amino acid / phenylalanine ABC transporter - membrane subunit
serA 1.81

rrsD-ileU-alaU-rrlD-rrfD-thrV-rrfF 1.37
rrlD
ileU
alaU
thrV
rrfF
rrsD
rrfD
rrlD 23S ribosomal RNA
tRNAileU
tRNAalaU
tRNAthrV
rrfF 5S ribosomal RNA
rrsD 16S ribosomal RNA
rrfD 5S ribosomal RNA
gcvTHP 1.19
gcvH
gcvP
gcvT
glycine cleavage system H protein
glycine decarboxylase
aminomethyltransferase
adhE 0.95
adhE
aldehyde-alcohol dehydrogenase
rrsC-gltU-rrlC-rrfC 0.94
rrlC
gltU
rrfC
rrsC
rrlC 23S ribosomal RNA
tRNAgltU
rrfC 5S ribosomal RNA
rrsC 16S ribosomal RNA
oppABCDF 0.91
oppA
oppC
oppB
oppD
oppF
peptide ABC transporter - periplasmic binding protein
murein tripeptide ABC transporter / peptide ABC transporter - putative membrane subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative membrane subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative ATP binding subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative ATP binding subunit
rrsH-ileV-alaV-rrlH-rrfH 0.90
rrlH
rrfH
rrsH
ileV
alaV
rrlH 23S ribosomal RNA
rrfH 5S ribosomal RNA
rrsH 16S ribosomal RNA
tRNAileV
tRNAalaV
avtA 0.87
avtA
valine-pyruvate aminotransferase
ilvLXG_1G_2MEDA 0.85
ilvE
ilvX
ilvM
ilvL
ilvG_1
ilvD
ilvG_2
ilvA
branched-chain amino-acid aminotransferase
small protein
acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit
ilvGEDA operon leader peptide
acetolactate synthase II, large subunit, N-ter fragment (pseudogene)
dihydroxy acid dehydratase
acetolactate synthase II, large subunit, C-ter fragment (pseudogene)
threonine deaminase
rrsG-gltW-rrlG-rrfG 0.80
rrlG
gltW
rrfG
rrsG
rrlG 23S ribosomal RNA
tRNAgltW
rrfG 5S ribosomal RNA
rrsG 16S ribosomal RNA
ilvL 0.68
ilvL
ilvGEDA operon leader peptide
lysP 0.58
lysP
lysine:H+ symporter
csiD-lhgO-gabDTP 0.33
gabD
lhgO
gabP
csiD
gabT
succinate-semialdehyde dehydrogenase (NADP+)
L-2-hydroxyglutarate oxidase
4-aminobutyrate:H+ symporter
predicted protein
4-aminobutyrate aminotransferase
rrsA-ileT-alaT-rrlA-rrfA 0.26
rrlA
ileT
alaT
rrsA
rrfA
23S ribosomal RNA (rrlA)
tRNAileT
tRNAalaT
16S ribosomal RNA (rrsA)
5S ribosomal RNA (rrfA)
osmY 0.22
osmY
periplasmic chaperone, osmotically induced
lysU 0.21
lysU
lysine-tRNA ligase / Ap4A synthetase / Ap3A synthetase
rrsB-gltT-rrlB-rrfB 0.20
rrlB
gltT
rrfB
rrsB
rrlB 23S ribosomal RNA
tRNAgltT
rrfB 5S ribosomal RNA
rrsB 16S ribosomal RNA
stpA 0.18
stpA
H-NS-like DNA-binding transcriptional repressor with RNA chaperone activity

Network of associatons between targets according to the STRING database.

First level regulatory network of Lrp

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.9 3.8 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.8 2.5 GO:0009098 leucine metabolic process(GO:0006551) leucine biosynthetic process(GO:0009098)
0.8 2.3 GO:0046417 chorismate metabolic process(GO:0046417)
0.7 2.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.5 1.6 GO:0009099 valine biosynthetic process(GO:0009099)
0.4 1.2 GO:0019464 glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3 0.9 GO:0006067 ethanol metabolic process(GO:0006067)
0.2 0.9 GO:0006857 oligopeptide transport(GO:0006857) oligopeptide transmembrane transport(GO:0035672)
0.1 0.5 GO:1902022 lysine transport(GO:0015819) L-lysine transport(GO:1902022)
0.1 0.3 GO:0006591 ornithine metabolic process(GO:0006591) arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.2 GO:0043039 tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 GO:1990234 transferase complex(GO:1990234)
0.2 1.9 GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)
0.1 1.2 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 4.9 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)
0.0 5.2 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0003984 acetolactate synthase activity(GO:0003984)
0.6 1.9 GO:0015192 L-phenylalanine transmembrane transporter activity(GO:0015192)
0.5 2.8 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.3 0.9 GO:0035673 oligopeptide transporter activity(GO:0015198) peptidoglycan transporter activity(GO:0015647) oligopeptide transmembrane transporter activity(GO:0035673)
0.1 2.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.3 GO:0004777 succinate-semialdehyde dehydrogenase (NAD+) activity(GO:0004777)
0.1 0.9 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 1.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.2 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)