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GSE67402: E.coli regulatory changes under long-term starvation

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Results for LeuO

Z-value: 0.47

Transcription factors associated with LeuO

Gene Symbol Gene ID Gene Info
leuO LeuO DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
leuO-0.403.8e-02Click!

Activity profile of LeuO motif

Sorted Z-values of LeuO motif

Promoter Log-likelihood Transcript Gene Gene Info
leuL 2.64 leu operon leader peptide
casABCDE12 1.78 crRNA endonuclease
Cascade subunit D
Cascade subunit A
Cascade subunit C
Cascade subunit B
multifunctional nuclease Cas1
Cas2 protein
bglG 1.24 BglG transcriptional antiterminator
yjjQ-bglJ 1.08 BglJ DNA-binding transcriptional regulator
YjjQ DNA-binding transcriptional repressor
leuLABCD 1.01 LeuD
3-isopropylmalate dehydrogenase
LeuC
2-isopropylmalate synthase
leu operon leader peptide
cadC 0.90 CadC DNA-binding transcriptional activator
leuO 0.21 LeuO DNA-binding transcriptional dual regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of LeuO

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0031556 leucine metabolic process(GO:0006551) leucine biosynthetic process(GO:0009098) transcriptional attenuation by ribosome(GO:0031556)
0.4 1.8 GO:0009607 defense response(GO:0006952) response to biotic stimulus(GO:0009607) response to virus(GO:0009615) response to external biotic stimulus(GO:0043207) response to other organism(GO:0051707) RNA phosphodiester bond hydrolysis(GO:0090501)
0.3 1.1 GO:1901654 response to methylglyoxal(GO:0051595) response to ketone(GO:1901654)
0.0 0.9 GO:0045893 positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA metabolic process(GO:0051254) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 GO:0044445 cytosolic part(GO:0044445)
0.0 1.8 GO:0043234 protein complex(GO:0043234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0016889 crossover junction endodeoxyribonuclease activity(GO:0008821) endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.3 1.0 GO:0046912 acetyl-CoA C-acyltransferase activity(GO:0003988) transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 1.2 GO:0003723 RNA binding(GO:0003723)
0.0 1.1 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)