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GSE67402: E.coli regulatory changes under long-term starvation

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Results for GntR

Z-value: 0.51

Transcription factors associated with GntR

Gene Symbol Gene ID Gene Info
gntR
gntR GntR DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gntR-0.413.1e-02Click!

Activity profile of GntR motif

Sorted Z-values of GntR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
gntT 4.50
gntT
gluconate transporter GntT
gntKU 2.61
gntK
gntU
D-gluconate kinase, thermostable
gluconate transporter GntU
gntK 2.23
gntK
D-gluconate kinase, thermostable
idnK 2.08
idnK
D-gluconate kinase, thermosensitive
edd-eda 0.37
eda
edd
multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase
phosphogluconate dehydratase
gntX-nfuA 0.12
gntX
nfuA
protein involved in utilization of DNA as a carbon source
iron-sulfur cluster scaffold protein

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.3 GO:0019521 D-gluconate metabolic process(GO:0019521) D-gluconate catabolic process(GO:0046177)
0.0 0.1 GO:0015976 carbon utilization(GO:0015976)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 6.1 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0046316 gluconokinase activity(GO:0046316)
0.9 3.5 GO:0042879 gluconate transmembrane transporter activity(GO:0015128) aldonate transmembrane transporter activity(GO:0042879)
0.0 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors