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GSE67402: E.coli regulatory changes under long-term starvation

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Results for GadW

Z-value: 0.32

Transcription factors associated with GadW

Gene Symbol Gene ID Gene Info
gadW GadW DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gadW-0.106.2e-01Click!
gadX-0.096.5e-01Click!

Activity profile of GadW motif

Sorted Z-values of GadW motif

Promoter Log-likelihood Transcript Gene Gene Info
gadY 2.56 GadY
gadX 0.96 GadX DNA-binding transcriptional dual regulator
gadBC 0.85 glutamate decarboxylase B subunit
glutamic acid:4-aminobutyrate antiporter
gadXW 0.84 GadW DNA-binding transcriptional dual regulator
GadX DNA-binding transcriptional dual regulator
slp-dctR 0.73 starvation lipoprotein
predicted DNA-binding transcriptional regulator
gadW 0.54 GadW DNA-binding transcriptional dual regulator
gadE-mdtEF 0.07 MdtEF-TolC multidrug efflux pump - permease subunit
MdtEF-TolC multidrug efflux pump - membrane fusion protein
GadE DNA-binding transcriptional activator

Network of associatons between targets according to the STRING database.

First level regulatory network of GadW

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043471 regulation of cellular catabolic process(GO:0031329) regulation of cellular carbohydrate catabolic process(GO:0043471)
0.2 0.7 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 1.8 GO:0051254 positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA metabolic process(GO:0051254) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0019867 outer membrane(GO:0019867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0001140 transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001140)
0.1 0.9 GO:0015297 antiporter activity(GO:0015297)