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GSE67402: E.coli regulatory changes under long-term starvation

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Results for FliZ

Z-value: 0.35

Transcription factors associated with FliZ

Gene Symbol Gene ID Gene Info
fliZ
fliZ FliZ DNA-binding transcriptional regulator

Activity profile of FliZ motif

Sorted Z-values of FliZ motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
csgDEFG 2.69
csgG
csgF
csgE
csgD
curli secretion channel
curli assembly component
curli transport specificity factor
CsgD DNA-binding transcriptional dual regulator
csgBAC 1.61
csgC
csgB
csgA
inhibitor of CsgA amyloid formation
curlin, minor subunit
curlin, major subunit
pdeR 0.80
pdeR
cyclic di-GMP phosphodiesterase
gadBC 0.67
gadB
gadC
glutamate decarboxylase B subunit
glutamic acid:4-aminobutyrate antiporter
flhDC 0.60
flhC
flhD
FlhC transcriptional dual regulator
FlhD transcriptional dual regulator
hdeAB-yhiD 0.54
yhiD
hdeB
hdeA
inner membrane protein YhiD
HdeB monomer
HdeA monomer, chaperone active form
gadE-mdtEF 0.29
mdtF
mdtE
gadE
MdtEF-TolC multidrug efflux pump - permease subunit
MdtEF-TolC multidrug efflux pump - membrane fusion protein
GadE DNA-binding transcriptional activator

Network of associatons between targets according to the STRING database.

First level regulatory network of FliZ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.3 GO:0022610 biological adhesion(GO:0022610)
0.2 0.7 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.5 GO:0071468 cellular response to acidic pH(GO:0071468)
0.1 0.8 GO:0043086 negative regulation of catalytic activity(GO:0043086)
0.0 0.3 GO:0006855 drug transmembrane transport(GO:0006855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0031246 intrinsic component of periplasmic side of cell outer membrane(GO:0031246)
0.2 1.6 GO:0042995 cell projection(GO:0042995)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0051087 chaperone binding(GO:0051087)
0.2 0.8 GO:0071111 cyclic-guanylate-specific phosphodiesterase activity(GO:0071111)
0.1 2.7 GO:0001159 bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.7 GO:0015297 antiporter activity(GO:0015297)
0.0 0.3 GO:0015238 drug transmembrane transporter activity(GO:0015238)