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GSE67402: E.coli regulatory changes under long-term starvation
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Results for FlhDC
Z-value: 1.17
Transcription factors associated with FlhDC
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
flhC
|
flhC | DNA-binding transcriptional dual regulator FlhC |
|
flhD
|
flhD | DNA-binding transcriptional dual regulator FlhD |
Activity-expression correlation:
Activity profile of FlhDC motif
Sorted Z-values of FlhDC motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| flgBCDEFGHIJ | 33.15 |
flgC
flgB
flgG
flgF
flgE
flgD
flgJ
flgI
flgH
|
flagellar basal-body rod protein FlgC flagellar basal-body rod protein FlgB flagellar basal-body rod protein FlgG flagellar basal-body rod protein FlgF flagellar hook protein FlgE flagellar biosynthesis, initiation of hook assembly FlgJ flagellar P-ring protein FlgI flagellar L-ring protein FlgH; basal-body outer-membrane L (lipopolysaccharide layer) ring protein |
|
| flgKL | 21.98 |
flgK
flgL
|
flagellar biosynthesis, hook-filament junction protein 1 flagellar biosynthesis; hook-filament junction protein |
|
| flhBAE | 18.93 |
flhB
flhA
flhE
|
flagellar biosynthesis protein FlhB flagellar biosynthesis protein FlhA flagellar protein |
|
| flgAMN | 17.91 |
flgA
flgN
flgM
|
flagellar biosynthesis; assembly of basal-body periplasmic P ring flagellar biosynthesis protein FlgN anti-sigma factor for FliA (σ28) |
|
| yecR | 14.55 |
yecR
|
predicted protein |
|
| mdh | 10.98 |
mdh
|
malate dehydrogenase |
|
| napFDAGHBC-ccmABCDEFGH | 4.37 |
napG
napF
napD
napC
ccmH
napA
ccmE
ccmD
ccmG
ccmF
ccmA
ccmC
ccmB
napH
napB
|
ferredoxin-type protein ferredoxin-type protein signal peptide-binding chaperone for NapA periplasmic nitrate reductase, cytochrome c protein holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmH large subunit of periplasmic nitrate reductase, molybdoprotein membrane anchored periplasmic heme chaperone CcmE ABC complex for formation and release of holoCcmE - membrane subunit CcmD holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmG holocytochrome c synthetase - CcmF subunit ABC complex for formation and release of holoCcmE - ATP binding subunit ABC complex for formation and release of holoCcmE - membrane subunit CcmC ABC complex for formation and release of holoCcmE - membrane subunit CcmB ferredoxin-type protein subunit of periplasmic nitrate reductase, cytochrome c550 protein |
|
| mglBAC | 2.96 |
mglA
mglB
mglC
|
D-galactose / D-galactoside ABC transporter - ATP binding subunit D-galactose / D-galactoside ABC transporter - periplasmic binding protein D-galactose / D-galactoside ABC transporter - membrane subunit |
|
| nrfABCDEFG | 2.62 |
nrfF
nrfG
nrfD
nrfE
nrfB
nrfC
nrfA
|
activator of formate-dependent nitrite reductase complex NrfG formate dependent nitrite reductase - NrfD subunit formate-dependent nitrite reductase; possible assembly function formate-dependent nitrite reductase - penta-heme cytochrome c formate-dependent nitrite reductase, 4Fe-4S subunit formate dependent nitrite reductase - NrfA subunit |
|
| ppdAB-ygdB-ppdC-recC | 2.00 |
ppdA
ppdB
ppdC
ygdB
recC
|
conserved protein conserved protein predicted protein predicted protein RecC |
Network of associatons between targets according to the STRING database.
First level regulatory network of FlhDC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 30.7 | GO:0044781 | bacterial-type flagellum assembly(GO:0044780) bacterial-type flagellum organization(GO:0044781) |
| 3.8 | 22.9 | GO:0071978 | bacterial-type flagellum-dependent swarming motility(GO:0071978) |
| 3.7 | 11.0 | GO:0006108 | malate metabolic process(GO:0006108) |
| 3.0 | 17.9 | GO:0030162 | regulation of proteolysis(GO:0030162) |
| 2.3 | 7.0 | GO:0018063 | protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063) |
| 1.0 | 3.0 | GO:0015765 | methylgalactoside transport(GO:0015765) |
| 0.7 | 2.0 | GO:0044355 | clearance of foreign intracellular DNA(GO:0044355) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.3 | 21.3 | GO:0009288 | bacterial-type flagellum(GO:0009288) |
| 1.5 | 4.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.7 | 2.0 | GO:0009338 | exodeoxyribonuclease V complex(GO:0009338) |
| 0.6 | 11.0 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 17.9 | GO:0016989 | sigma factor antagonist activity(GO:0016989) |
| 1.5 | 4.4 | GO:0005048 | signal sequence binding(GO:0005048) |
| 1.0 | 3.0 | GO:0015592 | methylgalactoside transmembrane transporter activity(GO:0015592) |
| 0.7 | 2.0 | GO:0008854 | exodeoxyribonuclease V activity(GO:0008854) |
| 0.7 | 2.6 | GO:0016662 | oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) |