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GSE67402: E.coli regulatory changes under long-term starvation

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Results for CusR

Z-value: 0.73

Transcription factors associated with CusR

Gene Symbol Gene ID Gene Info
cusR CusR transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cusR0.965.9e-16Click!

Activity profile of CusR motif

Sorted Z-values of CusR motif

Promoter Log-likelihood Transcript Gene Gene Info
cusCFBA 21.45 copper / silver exporter - membrane subunit
copper / silver exporter - outer membrane porin
copper / silver exporter - membrane fusion protein
copper / silver exporter - periplasmic binding protein and metallochaperone
cusRS 9.13 CusS sensory histidine kinase
CusR transcriptional activator
cyoABCDE 6.86 cytochrome bo terminal oxidase subunit II
cytochrome bo terminal oxidase subunit III
cytochrome bo terminal oxidase subunit I
heme O synthase
cytochrome bo terminal oxidase subunit IV

Network of associatons between targets according to the STRING database.

First level regulatory network of CusR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.2 30.6 GO:0010272 response to silver ion(GO:0010272)
1.7 6.9 GO:0019646 aerobic electron transport chain(GO:0019646) hydrogen ion transmembrane transport(GO:1902600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0070069 cytochrome complex(GO:0070069)
0.4 21.4 GO:0009279 cell outer membrane(GO:0009279)
0.0 9.1 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 21.4 GO:0016530 metallochaperone activity(GO:0016530)
3.0 9.1 GO:0009927 histidine phosphotransfer kinase activity(GO:0009927)
1.7 6.9 GO:0048039 prenyltransferase activity(GO:0004659) ubiquinone binding(GO:0048039)