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GSE67402: E.coli regulatory changes under long-term starvation

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Results for Ada

Z-value: 0.48

Transcription factors associated with Ada

Gene Symbol Gene ID Gene Info
ada
ada Ada DNA-binding transcriptional dual regulator / DNA repair protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ada-0.404.1e-02Click!

Activity profile of Ada motif

Sorted Z-values of Ada motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
aidB 8.54
aidB
isovaleryl-CoA dehydrogenase and DNA-binding transcriptional repressor
ada-alkB 4.65
alkB
ada
AlkB repair system for alkylated DNA and RNA
Ada DNA-binding transcriptional dual regulator / DNA repair protein

Network of associatons between targets according to the STRING database.

First level regulatory network of Ada

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.1 8.5 GO:1903507 negative regulation of transcription, DNA-templated(GO:0045892) negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.4 8.5 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage