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GSE67402: E.coli regulatory changes under long-term starvation

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Results for AcrR

Z-value: 0.45

Transcription factors associated with AcrR

Gene Symbol Gene ID Gene Info
acrR AcrR DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
acrR0.019.5e-01Click!

Activity profile of AcrR motif

Sorted Z-values of AcrR motif

Promoter Log-likelihood Transcript Gene Gene Info
soxS 3.84 SoxS DNA-binding transcriptional dual regulator
marRAB 2.61 multiple antibiotic resistance protein
MarA DNA-binding transcriptional dual regulator
MarR DNA-binding transcriptional repressor
soxR 0.90 SoxR DNA-binding transcriptional dual regulator
acrR 0.44 AcrR DNA-binding transcriptional repressor

Network of associatons between targets according to the STRING database.

First level regulatory network of AcrR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 4.3 GO:1903506 regulation of transcription, DNA-templated(GO:0006355) regulation of nucleic acid-templated transcription(GO:1903506) regulation of RNA biosynthetic process(GO:2001141)
0.0 0.9 GO:0006979 response to oxidative stress(GO:0006979)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0001098 basal transcription machinery binding(GO:0001098) bacterial-type RNA polymerase holo enzyme binding(GO:0001108)
0.1 0.4 GO:0008144 drug binding(GO:0008144)
0.1 2.6 GO:0001067 regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.1 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)