ISMARA results: TyrR

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for TyrR

Z-value: 2.25

Transcription factors associated with TyrR

Gene Symbol	Gene ID	Gene Info
tyrR RegulonDB EcoCyc	tyrR	TyrR DNA-binding transcriptional dual regulator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
tyrR		0.94	4.3e-04	Click!

Activity profile of TyrR motif

Sorted Z-values of TyrR motif

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Promoter	Log-likelihood	Gene	Gene Info
aroP Show fit	27.50	aroP RegulonDB EcoCyc Show fit	aromatic amino acid:H⁺ symporter AroP
tyrP Show fit	9.24	tyrP RegulonDB EcoCyc Show fit	tyrosine:H⁺ symporter TyrP
tyrB Show fit	6.48	tyrB RegulonDB EcoCyc Show fit	tyrosine aminotransferase
tyrR Show fit	4.70	tyrR RegulonDB EcoCyc Show fit	TyrR DNA-binding transcriptional dual regulator
mtr Show fit	4.30	mtr RegulonDB EcoCyc Show fit	tryptohan / indole:H+ symporter Mtr
aroG Show fit	2.00	aroG RegulonDB EcoCyc Show fit	2-dehydro-3-deoxyphosphoheptonate aldolase
aroL-yaiA-aroM Show fit	1.72	yaiA RegulonDB EcoCyc Show fit aroL RegulonDB EcoCyc Show fit aroM RegulonDB EcoCyc Show fit	predicted protein shikimate kinase II conserved protein
aroF-tyrA Show fit	0.02	tyrA RegulonDB EcoCyc Show fit aroF RegulonDB EcoCyc Show fit	chorismate mutase / prephenate dehydrogenase 2-dehydro-3-deoxyphosphoheptonate aldolase

Showing 1 to 8 of 8 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of TyrR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
10.6	31.8	GO:0015827	tryptophan transport(GO:0015827)
2.2	6.5	GO:0006570	tyrosine metabolic process(GO:0006570) tyrosine biosynthetic process(GO:0006571)
0.1	4.7	GO:0045892	negative regulation of transcription, DNA-templated(GO:0045892) negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)
0.3	3.7	GO:0009073	aromatic amino acid family biosynthetic process(GO:0009073)

Showing 1 to 4 of 4 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	41.0	GO:0005887	integral component of plasma membrane(GO:0005887)
0.0	12.3	GO:0005829	cytosol(GO:0005829)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
10.6	31.8	GO:0015196	L-tryptophan transmembrane transporter activity(GO:0015196)
0.4	6.5	GO:0008483	transaminase activity(GO:0008483)
0.1	4.7	GO:0005524	ATP binding(GO:0005524)
0.7	2.0	GO:0003849	3-deoxy-7-phosphoheptulonate synthase activity(GO:0003849)
0.0	1.7	GO:0000287	magnesium ion binding(GO:0000287)

Showing 1 to 5 of 5 entries

Results for TyrR

Z-value: 2.25

Transcription factors associated with TyrR

Activity-expression correlation:

Activity profile of TyrR motif

Sorted Z-values of TyrR motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TyrR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: