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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for Sigma28
Z-value: 3.10
Transcription factors associated with Sigma28
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| ynjH Show fit | 17.30 |
predicted protein |
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| yhiL Show fit | 15.21 |
predicted protein |
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| trg Show fit | 13.07 |
|
|
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| ves Show fit | 11.13 |
conserved protein |
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| flxA Show fit | 10.24 |
Qin prophage; predicted protein |
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| crfC-yjcZ Show fit | 9.27 |
clamp-binding sister replication fork colocalization protein conserved protein |
||
| aer Show fit | 7.94 |
aerotaxis sensor receptor, flavoprotein |
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| tar-tap-cheRBYZ Show fit | 7.69 |
chemotaxis protein methyltransferase/chemotaxis protein methyltransferase/chemotaxis protein methyltransferase/chemotaxis protein methyltransferase/chemotaxis protein methyltransferase CheZ chemotaxis regulator transmitting signal to flagellar motor component CheB |
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| fliC Show fit | 7.32 |
flagellar biosynthesis; flagellin, filament structural protein |
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| fliDST Show fit | 6.53 |
flagellar biosynthesis protein FliT flagellar cap protein FliD; filament capping protein; enables filament assembly flagellar biosynthesis protein FliS |
Network of associatons between targets according to the STRING database.
First level regulatory network of Sigma28
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 15.7 | GO:0097588 | cilium or flagellum-dependent cell motility(GO:0001539) bacterial-type flagellum-dependent cell motility(GO:0071973) archaeal or bacterial-type flagellum-dependent cell motility(GO:0097588) |
| 2.8 | 13.8 | GO:0042330 | chemotaxis(GO:0006935) taxis(GO:0042330) |
| 3.0 | 12.2 | GO:0050918 | positive chemotaxis(GO:0050918) |
| 1.2 | 9.3 | GO:0007059 | chromosome segregation(GO:0007059) |
| 0.7 | 6.1 | GO:0006805 | xenobiotic metabolic process(GO:0006805) response to xenobiotic stimulus(GO:0009410) cellular response to xenobiotic stimulus(GO:0071466) |
| 1.2 | 4.7 | GO:0044781 | bacterial-type flagellum assembly(GO:0044780) bacterial-type flagellum organization(GO:0044781) |
| 0.7 | 3.5 | GO:0030162 | regulation of proteolysis(GO:0030162) |
| 0.1 | 1.5 | GO:0015698 | inorganic anion transport(GO:0015698) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 15.0 | GO:0005886 | plasma membrane(GO:0005886) |
| 3.0 | 12.2 | GO:0044461 | bacterial-type flagellum part(GO:0044461) cell projection part(GO:0044463) |
| 0.1 | 4.4 | GO:0030288 | outer membrane-bounded periplasmic space(GO:0030288) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 14.4 | GO:0005515 | protein binding(GO:0005515) |
| 0.4 | 7.9 | GO:0004871 | signal transducer activity(GO:0004871) |
| 0.5 | 7.7 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 1.2 | 6.2 | GO:0071111 | cyclic-guanylate-specific phosphodiesterase activity(GO:0071111) |
| 0.1 | 5.9 | GO:0016788 | hydrolase activity, acting on ester bonds(GO:0016788) |
| 0.7 | 3.3 | GO:0035438 | cyclic nucleotide binding(GO:0030551) cyclic-di-GMP binding(GO:0035438) |
| 0.2 | 1.8 | GO:0016989 | sigma factor antagonist activity(GO:0016989) |
| 0.2 | 1.5 | GO:0043225 | molybdenum ion binding(GO:0030151) anion transmembrane-transporting ATPase activity(GO:0043225) |