ISMARA results: SgrR

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for SgrR

Z-value: 0.73

Transcription factors associated with SgrR

Gene Symbol	Gene ID	Gene Info
sgrR RegulonDB EcoCyc	sgrR	SgrR DNA-binding transcriptional dual regulator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
sgrR		0.91	1.7e-03	Click!

Activity profile of SgrR motif

Sorted Z-values of SgrR motif

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Promoter	Log-likelihood	Gene	Gene Info
sgrR-sroA-tbpA-thiPQ Show fit	3.10	thiP RegulonDB EcoCyc Show fit tbpA RegulonDB EcoCyc Show fit thiQ RegulonDB EcoCyc Show fit sgrR RegulonDB EcoCyc Show fit sroA RegulonDB EcoCyc Show fit	thiamin ABC transporter - membrane subunit thiamin ABC transporter - periplasmic binding protein thiamin ABC transporter - ATP binding subunit SgrR DNA-binding transcriptional dual regulator SroA
sgrST-setA Show fit	2.07	sgrT RegulonDB EcoCyc Show fit setA RegulonDB EcoCyc Show fit sgrS RegulonDB EcoCyc Show fit	SgrT, regulator of PtsG activity sugar / lactose exporter SetA SgrS
alaC Show fit	1.83	alaC RegulonDB EcoCyc Show fit	glutamate-pyruvate aminotransferase

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Network of associatons between targets according to the STRING database.

First level regulatory network of SgrR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	3.1	GO:0045117	azole transport(GO:0045117)
0.5	2.1	GO:0015758	glucose transport(GO:0015758) glucose import(GO:0046323)
0.6	1.8	GO:0046145	alanine biosynthetic process(GO:0006523) pyruvate family amino acid biosynthetic process(GO:0009079) D-alanine biosynthetic process(GO:0030632) L-alanine biosynthetic process(GO:0042852) D-alanine family amino acid biosynthetic process(GO:0046145) D-amino acid biosynthetic process(GO:0046437)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	GO:0098533	ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	3.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.3	2.1	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.1	1.8	GO:0008483	transaminase activity(GO:0008483)

Showing 1 to 3 of 3 entries

Results for SgrR

Z-value: 0.73

Transcription factors associated with SgrR

Activity-expression correlation:

Activity profile of SgrR motif

Sorted Z-values of SgrR motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of SgrR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: