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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for SgrR

Z-value: 0.73

Transcription factors associated with SgrR

Gene Symbol Gene ID Gene Info
sgrR SgrR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sgrR0.911.7e-03Click!

Activity profile of SgrR motif

Sorted Z-values of SgrR motif

Promoter Log-likelihood Transcript Gene Gene Info
sgrR-sroA-tbpA-thiPQ 3.10 thiamin ABC transporter - membrane subunit
thiamin ABC transporter - periplasmic binding protein
thiamin ABC transporter - ATP binding subunit
SgrR DNA-binding transcriptional dual regulator
SroA
sgrST-setA 2.07 SgrT, regulator of PtsG activity
sugar / lactose exporter SetA
SgrS
alaC 1.83 glutamate-pyruvate aminotransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of SgrR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0045117 azole transport(GO:0045117)
0.6 1.8 GO:0046145 alanine biosynthetic process(GO:0006523) pyruvate family amino acid biosynthetic process(GO:0009079) D-alanine biosynthetic process(GO:0030632) L-alanine biosynthetic process(GO:0042852) D-alanine family amino acid biosynthetic process(GO:0046145) D-amino acid biosynthetic process(GO:0046437)
0.5 2.1 GO:0015758 glucose transport(GO:0015758) glucose import(GO:0046323)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 GO:0098533 ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.3 2.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 1.8 GO:0008483 transaminase activity(GO:0008483)