Project

GSE55662: Plasticity of transcriptional regulation under antibiotic stress

Navigation
Downloads

Results for Rob

Z-value: 0.60

Transcription factors associated with Rob

Gene Symbol Gene ID Gene Info
rob
rob Rob DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rob0.782.1e-02Click!

Activity profile of Rob motif

Sorted Z-values of Rob motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
sodA 3.18
sodA
superoxide dismutase (Mn)
tolC-ygiABC 1.91
ygiC
ygiB
ygiA
tolC
predicted enzyme with ATPase activity
conserved outer membrane protein
predicted protein
TolC outer membrane channel
rob 1.46
rob
Rob DNA-binding transcriptional dual regulator
zwf 1.45
zwf
glucose-6-phosphate dehydrogenase (NADP+)
ldtB 1.38
ldtB
L,D-transpeptidase YbiS
micF 1.23
micF
MicF
fumC 0.80
fumC
fumarase C
acrAB 0.73
acrB
acrA
AcrAB-TolC multidrug efflux pump - permease subunit
AcrAB-TolC multidrug efflux pump - membrane fusion protein
ybjC-nfsA-rimK-ybjN 0.57
nfsA
ybjN
ybjC
rimK
NADPH nitroreductase NfsA
predicted oxidoreductase
predicted inner membrane protein
ribosomal protein S6 modification protein
nfo 0.55
nfo
endonuclease IV
nfsB 0.26
nfsB
NAD(P)H nitroreductase NfsB

Network of associatons between targets according to the STRING database.

First level regulatory network of Rob

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0006801 response to superoxide(GO:0000303) superoxide metabolic process(GO:0006801)
0.5 1.5 GO:0009372 quorum sensing(GO:0009372)
0.5 1.4 GO:0043164 Gram-negative-bacterium-type cell wall biogenesis(GO:0043164)
0.3 1.9 GO:0015891 siderophore transport(GO:0015891)
0.3 0.8 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.6 GO:1900232 negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) post-translational protein modification(GO:0043687) response to alcohol(GO:0097305) regulation of single-species biofilm formation on inanimate substrate(GO:1900231) negative regulation of single-species biofilm formation on inanimate substrate(GO:1900232) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209)
0.1 0.6 GO:0006284 base-excision repair(GO:0006284)
0.1 0.3 GO:0046263 trinitrotoluene metabolic process(GO:0018973) 2,4,6-trinitrotoluene metabolic process(GO:0018974) nitrotoluene metabolic process(GO:0019326) 2,4,6-trinitrotoluene catabolic process(GO:0046256) trinitrotoluene catabolic process(GO:0046260) nitrotoluene catabolic process(GO:0046263) toluene-containing compound metabolic process(GO:0072490) toluene-containing compound catabolic process(GO:0072491)
0.1 0.7 GO:0006855 drug transmembrane transport(GO:0006855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 GO:1990351 transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351)
0.0 6.3 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 1.4 GO:0016807 cysteine-type peptidase activity(GO:0008234) cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) peptidoglycan L,D-transpeptidase activity(GO:0071972)
0.3 1.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 0.7 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.2 0.6 GO:0034567 chromate reductase activity(GO:0034567)
0.2 0.8 GO:0004333 fumarate hydratase activity(GO:0004333)
0.1 0.6 GO:0008081 endodeoxyribonuclease activity(GO:0004520) phosphoric diester hydrolase activity(GO:0008081)
0.0 0.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 1.5 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 1.5 GO:0043565 sequence-specific DNA binding(GO:0043565)