ISMARA results: PuuR

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for PuuR

Z-value: 0.99

Transcription factors associated with PuuR

Gene Symbol	Gene ID	Gene Info
puuR RegulonDB EcoCyc	puuR	PuuR DNA-binding transcriptional repressor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
puuR		0.95	2.6e-04	Click!

Activity profile of PuuR motif

Sorted Z-values of PuuR motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
puuAP Show fit	9.00		puuP RegulonDB EcoCyc Show fit puuA RegulonDB EcoCyc Show fit	putrescine:H⁺ symporter PuuP glutamate-putrescine ligase
puuDRCBE Show fit	5.02		puuR RegulonDB EcoCyc Show fit puuC RegulonDB EcoCyc Show fit puuB RegulonDB EcoCyc Show fit puuD RegulonDB EcoCyc Show fit puuE RegulonDB EcoCyc Show fit	PuuR DNA-binding transcriptional repressor γ-glutamyl-γ-aminobutyraldehyde dehydrogenase γ-glutamylputrescine oxidase γ-glutamyl-γ-aminobutyrate hydrolase 4-aminobutyrate aminotransferase

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Network of associatons between targets according to the STRING database.

First level regulatory network of PuuR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.0	9.0	GO:0015846	polyamine transport(GO:0015846) putrescine transport(GO:0015847)
1.3	5.0	GO:0009447	polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	9.0	GO:0005886	plasma membrane(GO:0005886)
0.0	5.0	GO:0005737	cytoplasm(GO:0005737)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.5	9.0	GO:0016880	organic cation transmembrane transporter activity(GO:0015101) acid-ammonia (or amide) ligase activity(GO:0016880)
1.3	5.0	GO:0003867	4-aminobutyrate transaminase activity(GO:0003867)

Showing 1 to 2 of 2 entries

Results for PuuR

Z-value: 0.99

Transcription factors associated with PuuR

Activity-expression correlation:

Activity profile of PuuR motif

Sorted Z-values of PuuR motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of PuuR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: