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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for PgrR

Z-value: 1.77

Transcription factors associated with PgrR

Gene Symbol Gene ID Gene Info
pgrR PgrR DNA-binding transcriptional repressor

Activity profile of PgrR motif

Sorted Z-values of PgrR motif

Promoter Log-likelihood Transcript Gene Gene Info
ycjY 13.64 predicted hydrolase
ycjY-ymjDC-mpaA 10.30 small protein
murein tripeptide amidase A
predicted hydrolase
predicted oxidoreductase
ycjXF-tyrR 8.25 TyrR DNA-binding transcriptional dual regulator
conserved protein
conserved inner membrane protein
tyrR 4.86 TyrR DNA-binding transcriptional dual regulator
ycjG 0.95 L-Ala-D/L-Glu epimerase

Network of associatons between targets according to the STRING database.

First level regulatory network of PgrR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0006027 aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027) peptidoglycan catabolic process(GO:0009253) peptide catabolic process(GO:0043171)
0.5 13.6 GO:0051301 cell division(GO:0051301)
0.2 13.1 GO:1902679 negative regulation of transcription, DNA-templated(GO:0045892) negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 23.4 GO:0005737 cytoplasm(GO:0005737)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.2 1.0 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855)
0.2 13.1 GO:0005524 ATP binding(GO:0005524)