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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for OxyR
Z-value: 0.99
Transcription factors associated with OxyR
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| oxyR | 0.88 | 4.0e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| ahpCF Show fit | 8.95 |
alkyl hydroperoxide reductase, AhpF component alkyl hydroperoxide reductase, AhpC component |
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| dps Show fit | 3.85 |
stationary phase nucleoid protein that sequesters iron and protects DNA from damage |
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| hcp-hcr Show fit | 3.70 |
NADH oxidoreductase hybrid-cluster protein |
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| uxuAB Show fit | 2.31 |
D-mannonate dehydratase D-mannonate oxidoreductase |
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| ychF Show fit | 1.93 |
ribosome-binding ATPase, inhibitor of catalase activity |
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| katG Show fit | 1.86 |
hydroperoxidase I |
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| oxyR Show fit | 1.65 |
OxyR DNA-binding transcriptional dual regulator |
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| gntP Show fit | 1.44 |
gluconate / fructuronate transporter GntP |
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| ybjC-nfsA-rimK-ybjN Show fit | 0.81 |
NADPH nitroreductase NfsA predicted oxidoreductase predicted inner membrane protein ribosomal protein S6 modification protein |
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| uof-fur Show fit | 0.24 |
Fur transcriptional dual regulator RyhB-regulated fur leader peptide |
Network of associatons between targets according to the STRING database.
First level regulatory network of OxyR
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 8.9 | GO:0009970 | cellular response to sulfate starvation(GO:0009970) |
| 0.1 | 3.9 | GO:0042594 | response to starvation(GO:0042594) |
| 1.2 | 3.7 | GO:0046209 | nitric oxide metabolic process(GO:0046209) nitric oxide catabolic process(GO:0046210) |
| 0.8 | 2.3 | GO:0006063 | uronic acid metabolic process(GO:0006063) |
| 0.4 | 1.9 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
| 0.1 | 1.6 | GO:2000142 | regulation of DNA-templated transcription, initiation(GO:2000142) |
| 0.5 | 1.4 | GO:0042873 | aldonate transport(GO:0042873) |
| 0.3 | 0.8 | GO:1902116 | negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) post-translational protein modification(GO:0043687) response to alcohol(GO:0097305) regulation of single-species biofilm formation on inanimate substrate(GO:1900231) negative regulation of single-species biofilm formation on inanimate substrate(GO:1900232) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 8.9 | GO:1990204 | oxidoreductase complex(GO:1990204) |
| 0.5 | 1.9 | GO:0005576 | extracellular region(GO:0005576) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 8.9 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.1 | 5.3 | GO:0005506 | iron ion binding(GO:0005506) |
| 0.3 | 3.7 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
| 0.6 | 1.9 | GO:0004096 | catalase activity(GO:0004096) |
| 0.2 | 1.9 | GO:0004857 | enzyme inhibitor activity(GO:0004857) |
| 0.1 | 1.6 | GO:0001131 | transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001131) |
| 0.3 | 1.4 | GO:0042879 | gluconate transmembrane transporter activity(GO:0015128) aldonate transmembrane transporter activity(GO:0042879) |
| 0.3 | 0.8 | GO:0034567 | chromate reductase activity(GO:0034567) |