ISMARA results: NrdR

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for NrdR

Z-value: 0.77

Transcription factors associated with NrdR

Gene Symbol	Gene ID	Gene Info
nrdR RegulonDB EcoCyc	nrdR	NrdR transcriptional repressor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
nrdR		0.76	2.8e-02	Click!

Activity profile of NrdR motif

Sorted Z-values of NrdR motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
nrdAB-yfaE Show fit	4.21		nrdA RegulonDB EcoCyc Show fit nrdB RegulonDB EcoCyc Show fit yfaE RegulonDB EcoCyc Show fit	ribonucleoside diphosphate reductase 1, α subunit ribonucleoside diphosphate reductase 1, β subunit, ferritin-like 2Fe-2S cluster-containing protein involved in diferric-tyrosyl radical cofactor maintenance
nrdDG Show fit	4.09		nrdD RegulonDB EcoCyc Show fit nrdG RegulonDB EcoCyc Show fit	anaerobic ribonucleoside-triphosphate reductase anaerobic ribonucleoside-triphosphate reductase-activating protein

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Network of associatons between targets according to the STRING database.

First level regulatory network of NrdR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	6.9	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.1	GO:0043234	protein complex(GO:0043234)
0.1	2.8	GO:1990204	oxidoreductase complex(GO:1990204)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.3	6.9	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)

Showing 1 to 1 of 1 entries

Results for NrdR

Z-value: 0.77

Transcription factors associated with NrdR

Activity-expression correlation:

Activity profile of NrdR motif

Sorted Z-values of NrdR motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of NrdR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: