ISMARA results: NikR

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for NikR

Z-value: 0.44

Transcription factors associated with NikR

Gene Symbol	Gene ID	Gene Info
nikR RegulonDB EcoCyc	nikR	NikR DNA-binding transcriptional repressor, Ni-binding

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
nikR		0.92	1.0e-03	Click!

Activity profile of NikR motif

Sorted Z-values of NikR motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
nikABCDER Show fit	2.46		nikB RegulonDB EcoCyc Show fit nikC RegulonDB EcoCyc Show fit nikA RegulonDB EcoCyc Show fit nikD RegulonDB EcoCyc Show fit nikE RegulonDB EcoCyc Show fit nikR RegulonDB EcoCyc Show fit	nickel ABC transporter - membrane subunit nickel ABC transporter - membrane subunit nickel ABC transporter - periplasmic binding protein nickel ABC transporter - ATP binding subunit nickel ABC transporter - ATP binding subunit NikR DNA-binding transcriptional repressor, Ni-binding

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Network of associatons between targets according to the STRING database.

First level regulatory network of NikR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0015675	nickel cation transport(GO:0015675) nickel cation transmembrane transport(GO:0035444)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.5	GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.5	GO:0015099	nickel cation transmembrane transporter activity(GO:0015099)

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Results for NikR

Z-value: 0.44

Transcription factors associated with NikR

Activity-expression correlation:

Activity profile of NikR motif

Sorted Z-values of NikR motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of NikR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: