ISMARA results: MurR

Project

GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for MurR

Z-value: 0.86

Transcription factors associated with MurR

Gene Symbol	Gene ID	Gene Info
murR RegulonDB EcoCyc	murR	MurR DNA-binding transcriptional dual regulator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
murR		0.90	2.3e-03	Click!

Activity profile of MurR motif

Sorted Z-values of MurR motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
murR Show fit	6.18		murR RegulonDB EcoCyc Show fit	MurR DNA-binding transcriptional dual regulator
murQP Show fit	2.67		murP RegulonDB EcoCyc Show fit murQ RegulonDB EcoCyc Show fit	N-acetylmuramic acid PTS permease / anhydro-N-acetylmuramic acid permease N-acetylmuramic acid 6-phosphate etherase

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Network of associatons between targets according to the STRING database.

First level regulatory network of MurR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.2	GO:1903507	negative regulation of transcription, DNA-templated(GO:0045892) negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)
0.7	2.7	GO:0009254	peptidoglycan turnover(GO:0009254)

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Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.2	GO:0005829	cytosol(GO:0005829)
0.0	2.7	GO:0005887	integral component of plasma membrane(GO:0005887)

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Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.2	GO:0003700	transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.9	2.7	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801) ether hydrolase activity(GO:0016803)

Showing 1 to 2 of 2 entries

Results for MurR

Z-value: 0.86

Transcription factors associated with MurR

Activity-expression correlation:

Activity profile of MurR motif

Sorted Z-values of MurR motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of MurR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: