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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for MqsA

Z-value: 0.60

Transcription factors associated with MqsA

Gene Symbol Gene ID Gene Info
mqsA
mqsA MqsA antitoxin of the MqsRA toxin-antitoxin system and DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mqsA0.206.4e-01Click!

Activity profile of MqsA motif

Sorted Z-values of MqsA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
cspD 5.29
cspD
DNA replication inhibitor
rpoS 3.44
rpoS
RNA polymerase, sigma S (sigma 38) factor

Network of associatons between targets according to the STRING database.

First level regulatory network of MqsA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0051053 negative regulation of DNA replication(GO:0008156) negative regulation of DNA metabolic process(GO:0051053)
0.7 3.4 GO:0001121 transcription from bacterial-type RNA polymerase promoter(GO:0001121)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 8.7 GO:0005737 cytoplasm(GO:0005737)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0001000 bacterial-type RNA polymerase core enzyme binding(GO:0001000)
0.5 5.3 GO:0003697 single-stranded DNA binding(GO:0003697)